Identification and Validation of an

Musashi Notch signaling RNA-binding proteins Wnt signaling cancer therapy drug discovery fungi secondary metabolite derivative

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
08 Aug 2020
Historique:
received: 01 04 2020
revised: 01 08 2020
accepted: 06 08 2020
entrez: 14 8 2020
pubmed: 14 8 2020
medline: 14 8 2020
Statut: epublish

Résumé

RNA-binding protein Musashi-1 (MSI1) is a key regulator of several stem cell populations. MSI1 is involved in tumor proliferation and maintenance, and it regulates target mRNAs at the translational level. The known mRNA targets of MSI1 include

Identifiants

pubmed: 32784494
pii: cancers12082221
doi: 10.3390/cancers12082221
pmc: PMC7463734
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NIH HHS
ID : AI074856
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM113117
Pays : United States
Organisme : Kansas Bioscience Authority
ID : Rising Star Award
Organisme : NIH HHS
ID : R01 CA178831
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA178831
Pays : United States
Organisme : NCRR NIH HHS
ID : P30 RR030926
Pays : United States
Organisme : National Institute of General Medical Science
ID : P01GM084077
Organisme : NCI NIH HHS
ID : P30 CA168524
Pays : United States
Organisme : the University of Kansas Endowment
ID : the Irving S. Johnson Fund
Organisme : NIGMS NIH HHS
ID : K12 GM063651
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA191785
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI074856
Pays : United States
Organisme : the University of Kansas
ID : Bold Aspiration Strategic Initiative Award
Organisme : NIH HHS
ID : R01 CA191785
Pays : United States

Références

PLoS One. 2013;8(1):e53540
pubmed: 23308249
Neuron. 1994 Jul;13(1):67-81
pubmed: 8043282
Indian J Exp Biol. 2012 Jul;50(7):464-8
pubmed: 22822525
J Cancer Prev. 2017 Dec;22(4):203-210
pubmed: 29302577
PLoS One. 2017 Apr 17;12(4):e0175471
pubmed: 28414767
Oncotarget. 2017 Nov 20;8(63):106587-106597
pubmed: 29290973
Mol Cell Neurosci. 2006 Jan;31(1):85-96
pubmed: 16214366
Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8265-70
pubmed: 12060769
Adv Exp Med Biol. 2013;786:233-45
pubmed: 23696360
Dev Neurosci. 2000;22(1-2):139-53
pubmed: 10657706
EMBO J. 2006 Jun 21;25(12):2792-801
pubmed: 16763568
Nat Commun. 2019 Jun 19;10(1):2691
pubmed: 31217428
J Biomol Screen. 1999;4(2):67-73
pubmed: 10838414
J Biol Chem. 2011 Feb 18;286(7):4946-50
pubmed: 21199875
Comb Chem High Throughput Screen. 2014;17(7):596-609
pubmed: 24912481
Cancer Biol Ther. 2010 Nov 15;10(10):979-82
pubmed: 21084860
ACS Chem Biol. 2015 Jun 19;10(6):1476-84
pubmed: 25750985
Mol Oncol. 2015 Aug;9(7):1406-20
pubmed: 25933687
Bioorg Med Chem. 1997 Jun;5(6):1173-84
pubmed: 9222511
Mol Cancer Ther. 2008 Jul;7(7):2192-202
pubmed: 18645028
J Med Chem. 2012 May 10;55(9):4132-41
pubmed: 22480197
Clin Cancer Res. 2017 May 1;23(9):2143-2153
pubmed: 28143872
Mol Cancer. 2010 Aug 21;9:221
pubmed: 20727204
Int J Colorectal Dis. 2010 Jan;25(1):17-23
pubmed: 19714342
Nucleic Acids Res. 2012 Apr;40(7):3218-31
pubmed: 22140116
Annu Rev Cell Dev Biol. 2015;31:249-67
pubmed: 26566113
Oncotarget. 2013 May;4(5):739-50
pubmed: 23715514
Org Lett. 2012 Feb 17;14(4):972-5
pubmed: 22296232
Bioorg Med Chem. 2010 Jun 1;18(11):3812-22
pubmed: 20466555
Cell. 1993 Sep 24;74(6):969-78
pubmed: 8402886
Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15194-9
pubmed: 12407178
Glia. 2001 Apr 1;34(1):1-7
pubmed: 11284014
Trends Cancer. 2017 May;3(5):347-356
pubmed: 28718412
BMC Cancer. 2018 Aug 10;18(1):809
pubmed: 30097032
Cell Death Differ. 2011 Jan;18(1):60-71
pubmed: 20577262
Nature. 2010 Aug 5;466(7307):765-8
pubmed: 20639863
Clin Cancer Res. 2013 Dec 15;19(24):6703-15
pubmed: 24132924
Differentiation. 2003 Jan;71(1):28-41
pubmed: 12558601
Am J Pathol. 2006 Jan;168(1):80-92
pubmed: 16400011
Biochem J. 1940 Nov;34(10-11):1418.1-1421
pubmed: 16747272
Nat Med. 2010 Aug;16(8):903-8
pubmed: 20616797
Biotechnol Lett. 2006 Oct;28(20):1633-6
pubmed: 16900332
J Chem Inf Model. 2013 Aug 26;53(8):2073-81
pubmed: 23879197
Nat Commun. 2015 Mar 16;6:6517
pubmed: 25774828
Mol Cell Biol. 2001 Jun;21(12):3888-900
pubmed: 11359897
FEMS Microbiol Lett. 2019 Jan 1;366(1):
pubmed: 30517616
Nat Rev Cancer. 2014 Apr;14(4):248-62
pubmed: 24622521
Neuron. 2010 Aug 12;67(3):407-21
pubmed: 20696379
Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):6955-60
pubmed: 27274057
RNA. 2011 Jan;17(1):14-20
pubmed: 21098142
J Cell Sci. 2010 Oct 1;123(Pt 19):3256-65
pubmed: 20826465
J Biol Chem. 2009 Mar 27;284(13):8654-60
pubmed: 19179334
BMC Cancer. 2008 Apr 18;8:108
pubmed: 18419830
Front Biosci (Landmark Ed). 2012 Jan 01;17:54-64
pubmed: 22201732
Mol Cancer Res. 2012 Jan;10(1):143-55
pubmed: 22258704
Nat Struct Biol. 2003 Aug;10(8):614-21
pubmed: 12858164
Dev Biol. 1996 Jun 15;176(2):230-42
pubmed: 8660864
Gastroenterology. 2008 May;134(5):1448-58
pubmed: 18471519
Cell Rep. 2015 Dec 22;13(11):2440-2455
pubmed: 26673327
J Biol Chem. 2006 Jun 30;281(26):17751-7
pubmed: 16798748
Gastroenterology. 2014 Apr;146(4):1108-18
pubmed: 24397969

Auteurs

Lan Lan (L)

Departments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.

Jiajun Liu (J)

Departments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.

Minli Xing (M)

Bio-NMR Core Facility, the University of Kansas, Lawrence, KS 66045, USA.

Amber R Smith (AR)

Departments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.

Jinan Wang (J)

Center for Computational Biology, the University of Kansas, Lawrence, KS 66045, USA.

Xiaoqing Wu (X)

Departments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.

Carl Appelman (C)

Departments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.

Ke Li (K)

Departments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.

Anuradha Roy (A)

High Throughput Screening Laboratory, the University of Kansas, Lawrence, KS 66045, USA.

Ragul Gowthaman (R)

Center for Computational Biology, the University of Kansas, Lawrence, KS 66045, USA.

John Karanicolas (J)

Program in Molecular Therapeutics, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.

Amber D Somoza (AD)

Department of Chemistry, University of Southern California, Los Angeles, CA 90007, USA.

Clay C C Wang (CCC)

Department of Chemistry, University of Southern California, Los Angeles, CA 90007, USA.
Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA 90007, USA.

Yinglong Miao (Y)

Center for Computational Biology, the University of Kansas, Lawrence, KS 66045, USA.

Roberto De Guzman (R)

Departments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.

Berl R Oakley (BR)

Departments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.

Kristi L Neufeld (KL)

Departments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.
Department of Cancer Biology, the University of Kansas Cancer Center, Kansas City, KS 66160, USA.

Liang Xu (L)

Departments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.
Department of Radiation Oncology, the University of Kansas Cancer Center, Kansas City, KS 66160, USA.

Classifications MeSH