Iron Oxide Mediated Photothermal Therapy in the Second Biological Window: A Comparative Study between Magnetite/Maghemite Nanospheres and Nanoflowers.
magnetic nanoflowers
magnetic nanoparticles
nanothermal therapies
photothermia
second biological window
Journal
Nanomaterials (Basel, Switzerland)
ISSN: 2079-4991
Titre abrégé: Nanomaterials (Basel)
Pays: Switzerland
ID NLM: 101610216
Informations de publication
Date de publication:
07 Aug 2020
07 Aug 2020
Historique:
received:
21
07
2020
revised:
02
08
2020
accepted:
05
08
2020
entrez:
14
8
2020
pubmed:
14
8
2020
medline:
14
8
2020
Statut:
epublish
Résumé
The photothermal use of iron oxide magnetic nanoparticles (NPs) is becoming more and more popular and documented. Herein, we compared the photothermal (PT) therapy potential versus magnetic hyperthermia (MHT) modality of magnetic nanospheres, largely used in the biomedical field and magnetic multicore nanoflowers known among the best nanoheaters. The NPs were imaged using transmission electron microscopy and their optical properties characterized by UV-Vis-NIR-I-II before oxidation (magnetite) and after oxidation to maghemite. The efficiency of all NPs in MHT and PT in the preferred second near-infrared (NIR-II) biological window was carried out in water and in cancer cells. We show that, in water, magnetite nanoflowers are the most efficient nanoheaters for both modalities. Moreover, PT appears much more efficient than MHT at low NP dose, whatever the NP. In the cellular environment, for PT, efficiency was totally conserved, with magnetite nanoflowers as the best performers compared to MHT, which was totally lost. Finally, cell uptake was significantly increased for the nanoflowers compared to the nanospheres. Finally, the antitumor therapy was investigated for all NPs at the same dose delivered to the cancer cells and at reasonable laser power density (0.3 W/cm
Identifiants
pubmed: 32784579
pii: nano10081548
doi: 10.3390/nano10081548
pmc: PMC7466508
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
ACS Nano. 2016 Feb 23;10(2):2436-46
pubmed: 26766814
Adv Mater. 2014 May;26(17):2694-8, 2016
pubmed: 24615901
Adv Drug Deliv Rev. 2019 Jan 1;138:68-104
pubmed: 30553951
ACS Nano. 2012 Dec 21;6(12):10935-49
pubmed: 23167525
Lasers Surg Med. 2018 Dec;50(10):1025-1033
pubmed: 30024039
Biomaterials. 2011 Oct;32(30):7600-8
pubmed: 21745689
J Mater Chem B. 2018 Sep 28;6(36):5689-5697
pubmed: 32254975
Adv Drug Deliv Rev. 2019 Jan 1;138:233-246
pubmed: 30414493
Chem Mater. 2019 Aug 13;31(15):5450-5463
pubmed: 31631940
Chem Commun (Camb). 2012 May 28;48(43):5319-21
pubmed: 22523747
Environ Sci Technol. 2012 Nov 20;46(22):12399-407
pubmed: 22577839
Chem Commun (Camb). 2015 Dec 11;51(95):16904-7
pubmed: 26435272
Adv Drug Deliv Rev. 2010 Mar 8;62(3):284-304
pubmed: 19909778
Nanoscale. 2015 Dec 7;7(45):18872-7
pubmed: 26468627
Nanoscale. 2015 Aug 7;7(29):12689-97
pubmed: 26151814
J Phys Chem Lett. 2015 Mar 19;6(6):970-4
pubmed: 26262854
Nanomedicine. 2015 Apr;11(3):645-55
pubmed: 25596340
Inorg Chem. 2017 Jul 17;56(14):8232-8243
pubmed: 28671822
Theranostics. 2019 Feb 12;9(5):1288-1302
pubmed: 30867831
Acc Chem Res. 2018 May 15;51(5):999-1013
pubmed: 29733199
ACS Nano. 2018 Mar 27;12(3):2741-2752
pubmed: 29508990
Biomaterials. 2008 Oct;29(30):4137-45
pubmed: 18667235
Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4044-4053
pubmed: 30760598
Nanotechnology. 2020 Feb 21;31(9):095705
pubmed: 31715590
Nanomedicine (Lond). 2011 Oct;6(8):1353-63
pubmed: 21651443
J Control Release. 2018 Jun 10;279:271-281
pubmed: 29684497
Adv Drug Deliv Rev. 2011 Aug 14;63(9):789-808
pubmed: 21447363
Adv Mater. 2011 Dec 1;23(45):5392-7
pubmed: 21997882
Biomaterials. 2013 May;34(16):4078-4088
pubmed: 23465836