Therapeutic Potential of Selenium as a Component of Preservation Solutions for Kidney Transplantation.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
07 Aug 2020
Historique:
received: 20 06 2020
revised: 28 07 2020
accepted: 05 08 2020
entrez: 14 8 2020
pubmed: 14 8 2020
medline: 9 3 2021
Statut: epublish

Résumé

Selenium has strong antioxidant properties and diverse effects on the immune system. The aim of the study was to analyse the protective effect of selenium as a component of a kidney preservation solution on the prevention of ischemia-reperfusion injury of nephrons. The solution was modified by the addition of Se (1 µg/L), prolactin (0.1 µg/L) and Se with prolactin (1 µg/L Se + 0.1 µg/L PRL). The study used a model for storing isolated porcine kidneys in Biolasol

Identifiants

pubmed: 32784639
pii: molecules25163592
doi: 10.3390/molecules25163592
pmc: PMC7463670
pii:
doi:

Substances chimiques

Solutions 0
Urea 8W8T17847W
Aspartate Aminotransferases EC 2.6.1.1
Alanine Transaminase EC 2.6.1.2
Selenium H6241UJ22B

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Aneta Ostróżka-Cieślik (A)

Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Kasztanowa 3, 41-200 Sosnowiec, Poland.

Barbara Dolińska (B)

Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Kasztanowa 3, 41-200 Sosnowiec, Poland.
"Biochefa" Pharmaceutical Research and Production Plant, Kasztanowa 3, 41-200 Sosnowiec, Poland.

Florian Ryszka (F)

"Biochefa" Pharmaceutical Research and Production Plant, Kasztanowa 3, 41-200 Sosnowiec, Poland.

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Classifications MeSH