Foetal therapies and their influence on preterm birth.

Fetoscopy Foetal medicine Foetal surgery Foetal therapy Premature rupture of membranes Preterm birth

Journal

Seminars in immunopathology
ISSN: 1863-2300
Titre abrégé: Semin Immunopathol
Pays: Germany
ID NLM: 101308769

Informations de publication

Date de publication:
08 2020
Historique:
received: 29 06 2020
accepted: 26 07 2020
pubmed: 14 8 2020
medline: 25 5 2021
entrez: 14 8 2020
Statut: ppublish

Résumé

Foetal therapy aims to improve perinatal survival or to prevent severe long-term handicap. Foetal medicine opens a new territory by treating the foetus as a patient. The mother has nothing to gain in terms of health benefits, yet she is inherently also undergoing treatment. In utero foetal interventions can be divided into ultrasound-guided minimally invasive procedures, fetoscopic procedures and open hysterotomy procedures, which carry an inherent risk of ruptured membranes and preterm birth. In this review, we summarise the conditions that may benefit from foetal therapy and review the current therapies on offer, each with their associated risk of ruptured membrane and preterm birth. We also look into some risk limiting and preventative strategies to mitigate these complications.

Identifiants

pubmed: 32785752
doi: 10.1007/s00281-020-00811-2
pii: 10.1007/s00281-020-00811-2
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

501-514

Subventions

Organisme : Fonds Wetenschappelijk Onderzoek
ID : 1804718N

Auteurs

Ignacio Valenzuela (I)

Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences, KU Leuven University of Leuven, Leuven, Belgium.

Johannes van der Merwe (J)

Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences, KU Leuven University of Leuven, Leuven, Belgium.
Department of Obstetrics and Gynaecology, Division Woman and Child, University Hospitals Leuven, Leuven, Belgium.

Luc De Catte (L)

Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences, KU Leuven University of Leuven, Leuven, Belgium.
Department of Obstetrics and Gynaecology, Division Woman and Child, University Hospitals Leuven, Leuven, Belgium.

Roland Devlieger (R)

Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences, KU Leuven University of Leuven, Leuven, Belgium.
Department of Obstetrics and Gynaecology, Division Woman and Child, University Hospitals Leuven, Leuven, Belgium.

Jan Deprest (J)

Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences, KU Leuven University of Leuven, Leuven, Belgium.
Department of Obstetrics and Gynaecology, Division Woman and Child, University Hospitals Leuven, Leuven, Belgium.
Institute for Women's Health, University College London, London, United Kingdom.

Liesbeth Lewi (L)

Department of Development and Regeneration, Cluster Woman and Child, Group Biomedical Sciences, KU Leuven University of Leuven, Leuven, Belgium. Liesbeth.lewi@uzleuven.be.
Department of Obstetrics and Gynaecology, Division Woman and Child, University Hospitals Leuven, Leuven, Belgium. Liesbeth.lewi@uzleuven.be.

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