Hemodynamic changes in neonates born to mothers with Graves' disease.

Cardiac output Echocardiography N-terminal-pro-B-type natriuretic peptide Neonatal hyperthyroidism Thyroid-stimulating hormone receptor antibody

Journal

Endocrine
ISSN: 1559-0100
Titre abrégé: Endocrine
Pays: United States
ID NLM: 9434444

Informations de publication

Date de publication:
04 2021
Historique:
received: 12 04 2020
accepted: 28 07 2020
pubmed: 14 8 2020
medline: 9 7 2021
entrez: 14 8 2020
Statut: ppublish

Résumé

Cardiac insufficiency is a major morbidity in neonatal hyperthyroidism. It is important to assess the hemodynamics in neonates born to mothers with Graves' disease (GD). This study prospectively evaluated the hemodynamic changes in neonates born to mothers with GD. Overall, 80 newborns were enrolled. Thirty-six neonates were born to mothers with GD who were positive for thyroid-stimulating hormone (TSH) receptor antibody (TRAb), and 44 were born to mother negative for TRAb. The serum levels of TSH, free triiodothyronine (FT The TRAb-positive newborns had higher FT Hemodynamic changes in neonates born to TRAb-positive mothers with GD resulted in a higher CI and NT-proBNP levels than in those with TRAb-negative mothers from postnatal days 5 to 10.

Identifiants

pubmed: 32785898
doi: 10.1007/s12020-020-02443-w
pii: 10.1007/s12020-020-02443-w
doi:

Substances chimiques

Triiodothyronine 06LU7C9H1V
Thyroxine Q51BO43MG4

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

171-178

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Auteurs

Takamichi Ishikawa (T)

Department of Pediatrics, Hamamatsu University School of Medicine, Shizuoka, Japan. ishikawa@hama-med.ac.jp.

Hiroki Uchiyama (H)

Department of Pediatrics, Hamamatsu University School of Medicine, Shizuoka, Japan.

Satoru Iwashima (S)

Department of Pediatrics, Hamamatsu University School of Medicine, Shizuoka, Japan.

Toru Baba (T)

Department of Pediatrics, Hamamatsu University School of Medicine, Shizuoka, Japan.

Akira Ohishi (A)

Department of Pediatrics, Hamamatsu University School of Medicine, Shizuoka, Japan.

Shigeo Iijima (S)

Department of Pediatrics, Hamamatsu University School of Medicine, Shizuoka, Japan.

Hiroaki Itoh (H)

Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Shizuoka, Japan.

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