Management of cardiac arrhythmias in patients with autoimmune disease-Insights from EHRA Young Electrophysiologists.


Journal

Pacing and clinical electrophysiology : PACE
ISSN: 1540-8159
Titre abrégé: Pacing Clin Electrophysiol
Pays: United States
ID NLM: 7803944

Informations de publication

Date de publication:
10 2020
Historique:
received: 22 05 2020
revised: 07 07 2020
accepted: 09 08 2020
pubmed: 14 8 2020
medline: 12 10 2021
entrez: 14 8 2020
Statut: ppublish

Résumé

Since arrhythmia treatment in patients with autoimmune disease (AD) is challenging, we aimed to assess the common "real-world" practice in the electrophysiology centers. Twenty-four young electrophysiologists being part of European Heart Rhythm Association filled questionnaire regarding arrhythmia management in AD. Rheumatoid arthritis was the most commonly reported AD accompanied by cardiac arrhythmias. The most frequent observed arrhythmias were atrial fibrillation and premature atrial/ventricular contractions. Most often electrocardiographic abnormalities observed were increased heart rate variability, QT interval prolongation, and P-wave dispersion, whereas echocardiographic abnormalities included left atrial enlargement, pericardial infusion, and left ventricular dysfunction. The most useful tool for arrhythmia management was guidelines and evidence-based medicine, while training courses and websites were at least useful. A close collaboration with other specialists in arrhythmia management was reported in 58.3% of respondents. Glucocorticoids and cytostatic were the most reported arrhythmia-induced drugs, whereas amiodarone and beta-blockers were most effective antiarrhythmic drugs. The main reason that discouraged respondents from cardiac implantable devices implantation and catheter ablation was high infection complications risk and recurrences during long-term follow-up, respectively. Scant data and guidelines enforce exchange of experience to improve the arrhythmia treatment in AD.

Sections du résumé

BACKGROUND
Since arrhythmia treatment in patients with autoimmune disease (AD) is challenging, we aimed to assess the common "real-world" practice in the electrophysiology centers.
METHODS
Twenty-four young electrophysiologists being part of European Heart Rhythm Association filled questionnaire regarding arrhythmia management in AD.
RESULTS
Rheumatoid arthritis was the most commonly reported AD accompanied by cardiac arrhythmias. The most frequent observed arrhythmias were atrial fibrillation and premature atrial/ventricular contractions. Most often electrocardiographic abnormalities observed were increased heart rate variability, QT interval prolongation, and P-wave dispersion, whereas echocardiographic abnormalities included left atrial enlargement, pericardial infusion, and left ventricular dysfunction. The most useful tool for arrhythmia management was guidelines and evidence-based medicine, while training courses and websites were at least useful. A close collaboration with other specialists in arrhythmia management was reported in 58.3% of respondents. Glucocorticoids and cytostatic were the most reported arrhythmia-induced drugs, whereas amiodarone and beta-blockers were most effective antiarrhythmic drugs. The main reason that discouraged respondents from cardiac implantable devices implantation and catheter ablation was high infection complications risk and recurrences during long-term follow-up, respectively.
CONCLUSIONS
Scant data and guidelines enforce exchange of experience to improve the arrhythmia treatment in AD.

Identifiants

pubmed: 32785936
doi: 10.1111/pace.14036
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1194-1198

Informations de copyright

© 2020 Wiley Periodicals LLC.

Références

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Priori SG, Blomstrom-Lundqvist C, Mazzanti A, et al. 2015 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: the task force for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death of the European Society of Cardiology (ESC). Endorsed by: association for European Paediatric and Congenital Cardiology (AEPC). Eur Heart J. 2015;36:2793-2867.
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Gawalko M, Balsam P, Lodzinski P, et al. Cardiac arrhythmias in autoimmune diseases. Circ J. 2020;84:685-694.
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Akikusa JD, Feldman BM, Gross GJ, Silverman ED, Schneider R. Sinus bradycardia after intravenous pulse methylprednisolone. Pediatrics. 2007;119:e778-e782.
Vasheghani-Farahani A, Sahraian MA, Darabi L, Aghsaie A, Minagar A. Incidence of various cardiac arrhythmias and conduction disturbances due to high dose intravenous methylprednisolone in patients with multiple sclerosis. J Neurol Sci. 2011;309:75-78.
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Auteurs

Monika Gawałko (M)

1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Department of Cardiology, Maastricht University Medical Centre+, Maastricht, The Netherlands.

Michał Peller (M)

1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.

Paweł Balsam (P)

1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.

Marcin Grabowski (M)

1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.

Jędrzej Kosiuk (J)

1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Rhythmology Department, Helios Clinic Koethen, Koethen, Germany.

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