Zinc deficiency limiting head growth to discharge in extremely low gestational age infants with insufficient linear growth: a cohort study.
Journal
Journal of perinatology : official journal of the California Perinatal Association
ISSN: 1476-5543
Titre abrégé: J Perinatol
Pays: United States
ID NLM: 8501884
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
15
04
2020
accepted:
03
08
2020
revised:
14
07
2020
pubmed:
14
8
2020
medline:
26
8
2021
entrez:
14
8
2020
Statut:
ppublish
Résumé
To assess the relationship of size for age with zinc deficiency in extremely low gestational age (GA) infants (23-28 weeks, ELGANs) who had insufficient linear growth despite optimizing other nutrients and to analyze changes in fronto-occipital circumference (FOC), weight and length with zinc supplementation. Retrospective cohort study. Among 302 ELGANs, a serum zinc concentration was obtained in 52 with insufficient linear growth (17%). Zinc deficiency (serum concentration <0.74 mcg/ml) was diagnosed in 8 of 24 (33%) small for GA (SGA) compared to 35 of 278 (13%) non-SGA infants (P = 0.01). Zinc supplementation for >2 weeks improved FOC growth to discharge or 50 weeks postmenstrual age in infants with Zn deficiency. However, neither linear growth nor weight gain improved with Zn supplementation. Zinc deficiency was diagnosed in 14% ELGANs in this cohort. Zinc supplementation for >2 weeks improved FOC growth but not linear growth or weight gain.
Identifiants
pubmed: 32788617
doi: 10.1038/s41372-020-00778-w
pii: 10.1038/s41372-020-00778-w
doi:
Substances chimiques
Zinc
J41CSQ7QDS
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1694-1704Références
Terrin G, Canani RB, Di Chiara M, Pietravalle A, Aleandri V, Conte F, et al. Zinc in early life: a key element in the fetus and preterm neonate. Nutrients. 2015;7:10427–46.
pubmed: 26690476
pmcid: 4690094
Sjöström ES, Öhlund I, Ahlsson F, Domellöf M. Intakes of micronutrients are associated with early growth in extremely preterm infants. J Pediatr Gastroenterol Nutr. 2016;62:885–92.
pubmed: 26690864
Harris T, Gardner F, Podany A, Kelleher SL, Doheny KK. Increased early enteral zinc intake improves weight gain in hospitalised preterm infants. Acta Paediatr. 2019;108:1978–84.
pubmed: 31033040
Georgieff MK, Ramel SE, Cusick SE. Nutritional influences on brain development. Acta Paediatr. 2018;107:1310–21.
pubmed: 29468731
pmcid: 6045434
Georgieff MK, Brunette KE, Tran PV. Early life nutrition and neural plasticity. Dev Psychopathol. 2015;27:411–23.
pubmed: 25997762
pmcid: 4443711
Cormack BE, Harding JE, Miller SP, Bloomfield FH. The influence of early nutrition on brain growth and neurodevelopment in extremely preterm babies: a narrative review. Nutrients. 2029; 11. https://www.mdpi.com/2072-6643/11/9/2029 .
Rozé JC, Darmaun D, Boquien CY, Flamant C, Picaud JC, Savagner C, et al. The apparent breastfeeding paradox in very preterm infants: relationship between breast feeding, early weight gain and neurodevelopment based on results from two cohorts, EPIPAGE and LIFT. BMJ Open. 2012;2:e000834.
pubmed: 22492388
pmcid: 22492388
Franz AR, Pohlandt F, Bode H, Mihatsch WA, Sander S, Kron M, et al. Intrauterine, early neonatal, and postdischarge growth and neurodevelopmental outcome at 5.4 years in extremely preterm infants after intensive neonatal nutritional support. Pediatrics. 2009;123:e101–9.
pubmed: 19117831
Neubauer V, Fuchs T, Griesmaier E, Kager K, Pupp-Peglow U, Kiechl-Kohlendorfer U. Poor postdischarge head growth is related to a 10% lower intelligence quotient in very preterm infants at the chronological age of five years. Acta Paediatr. 2016;105:501–7.
pubmed: 26792418
pmcid: 26792418
Neubauer V, Griesmaier E, Pehböck-Walser N, Pupp-Peglow U, Kiechl-Kohlendorfer U. Poor postnatal head growth in very preterm infants is associated with impaired neurodevelopment outcome. Acta Paediatr. 2013;102:883–8.
pubmed: 23772884
pmcid: 23772884
Pavageau L, Rosenfeld CR, Heyne R, Brown LS, Whitham J, Lair C, et al. Valid serial length measurements in preterm infants permit characterization of growth patterns. J Perinatol. 2018;38:1694–70.
pubmed: 30267002
pmcid: 30267002
Brion LP, Rosenfeld CR, Heyne R, Brown LS, Lair C, Burchfield P, et al. Adjustable feedings plus accurate serial length measurements decrease weight-length disproportion in very preterm infants. J Perinatol. 2019. https://doi.org/10.1038/s41372-019-0424-8 . PMID: 31263201; Correction: J Perinatol. 2019 Oct 10.
King JC, Brown KH, Gibson RS, Kreb NF, Lowe NM, Siekmann JH, et al. Biomarkers of nutrition for development (BOND)-zinc review. J Nutr. 2015;146:858S–85S.
pubmed: 26962190
Donangelo CM, King JC. Maternal zinc intakes and homeostatic adjustments during pregnancy and lactation. Nutrients. 2012;4:782–98.
pubmed: 22852063
pmcid: 3407994
Akdas S, Yazihan N. Cord blood zinc status effects on pregnancy outcomes and its relation with maternal serum zinc levels: a systematic review and meta-analysis. World J Pediatr. 2019. https://doi.org/10.1007/s12519-019-00305-8 .
Shaikhkhalil AK, Curtiss J, Puthoff TD, Valentine CJ. Enteral zinc supplementation and growth in extremely-low-birth-weight infants with chronic lung disease. J Pediatr Gastroenterol Nutr. 2014;58:183–7.
pubmed: 24121149
pmcid: 4125018
Brion LP, Rosenfeld CR, Heyne R, Brown LS, Lair CS, Heyne E, et al. Association of age of initiation and type and of complementary foods with body mass index and weight-length at twelve months of age in preterm infants. J Perinatol. 2020. https://doi.org/10.1038/s41372-020-0637-x .
Brion LP, Rosenfeld CR, Heyne R, Brown LS, Lair CS, Petrosyan E, et al. Optimizing individual nutrition in preterm very low birth weight infants: double-blinded randomized controlled trial. J Perinatol. 2020;40:655–65.
pubmed: 32071367
Finch CW. Review of trace mineral requirements for preterm infants: what are the current recommendations for clinical practice? Nutr Clin Pract. 2015;30:44–58.
pubmed: 25527182
Terrin G, Berni Canani R, Di Chiara M, Pietravalle A, Aleandri V, Conte F, et al. Zinc in early life: a key element in the fetus and preterm neonate. Nutrients. 2015;7:10427–46.
pubmed: 26690476
pmcid: 4690094
Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2001;163:1723–9.
Kliegman RM, Walsh MC. Neonatal necrotizing enterocolitis: pathogenesis, classification, and spectrum of illness. Curr Probl Pediatr. 1987;17:213–88.
pubmed: 3556038
Wester PO. Urinary zinc excretion during treatment with different diuretics. Acta Med Scand. 1980;208:209–12.
pubmed: 7001863
Fenton TR, Kim JH. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatr. 2013;13:59.
pubmed: 23601190
pmcid: 23601190
Ernst KD, Radmacher PG, Rafail ST, Adamkin DH. Postnatal malnutrition of extremely low birth-weight infants with catch-up growth postdischarge. J Perinatol. 2003;23:477–82.
pubmed: 13679935
Souza RT, Mayrink J, Leite DF, Costa ML, Calderon IM, Filho EAR, et al. Metabolomics applied to maternal and perinatal health: a review of new frontiers with a translation potential. Clinics. 2019;74:e894.
pubmed: 30916173
pmcid: 6438130
Gracie S, Pennell C, Ekman-Ordeberg G, Lyes S, McManaman J, Williams S, et al. An integrated systems biology approach to the study of preterm birth using “-omic” technology-a guideline for research. BMC Pregnancy Childbirth. 2011;11:71.
pubmed: 21992798
pmcid: 3205030
Krebs NF. Update on zinc deficiency and excess in clinical pediatric practice. Ann Nutr Metab. 2013;62:19–29.
pubmed: 23689110
de Benoist B, Darnton-Hill I, Davidsson L, Fontaine O, Hotz C. Conclusions of the joint WHO/UNICEF/IAEA/IZiNCG interagency meeting on zinc status indicators. Food Nutr Bull. 2007;28:S480–4.
pubmed: 17988008
Ota E, Mori R, Middleton P, Tobe‐Gai R, Mahomed K, Miyazaki C, et al. Zinc supplementation for improving pregnancy and infant outcome. Cochrane Database Syst Rev. 2015;2015:CD000230.
pmcid: 7043363
Díaz-Gómez NM, Doménech E, Barroso F, Castells S, Cortabarria C, Jiménez A. The effect of zinc supplementation on linear growth, body composition, and growth factors in preterm infants. Pediatrics. 2003;111:1002–9.
pubmed: 12728080
Sauer AK, Grabrucker AM. Zinc deficiency during pregnancy leads to altered microbiome and elevated inflammatory markers in mice. Front Neurosci. 2019;13:1295.
pubmed: 31849598
pmcid: 6895961
Buser JR, Maire J, Riddle A, Gong X, Nguyen T, Nelson K, et al. Arrested preoligodendrocyte maturation contributes to myelination failure in premature infants. Ann Neurol. 2012;71:93–109.
pubmed: 22275256
pmcid: 3270934
Segovia KN, McClure M, Moravec M, Luo NL, Wan Y, Gong X, et al. Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury. Ann Neurol. 2008;63:520–30.
pubmed: 18393269
pmcid: 3140464
Klein CJ. Nutrient requirements for preterm infant formulas. J Nutr. 2002;132:1395S–577S.
pubmed: 12042465
Domellöf D. Nutritional care of premature infants: Microminerals. [published correction appears in World Rev Nutr Diet. 2014;110:300-5]. World Rev Nutr Diet. 2014;110:121–39.
pubmed: 24751625
Griffin IJ, Domellöf M, Bhatia J, Anderson DM, Kler N. Zinc and copper requirements in preterm infants: an examination of the current literature. Early Hum Dev. 2013;89:S29–34.
pubmed: 23998450
Djurović D, Milisavljević B, Mugoša B, Lugonja N, Miletić S, Spasić S, et al. Zinc concentrations in human milk and infant serum during the first six months of lactation. J Trace Elem Med Biol. 2017;41:75–8.
pubmed: 28347466
Young BE, Borman LL, Heinrich R, Long J, Pinney S, Westcott J, et al. Effect of pooling practices and time postpartum of milk donations on the energy, macronutrient, and zinc concentrations of resultant donor human milk pools. J Pediatr. 2019;214:54–9.
pubmed: 31558278
pmcid: 6886691
Casey CE, Neville MC, Hambidge KM. Studies in human lactation: secretion of zinc, copper, and manganese in human milk. Am J Clin Nutr. 1989;49:773–85.
pubmed: 2718914
Terrin G, Canani RB, Passariello A, Messina F, Conti MG, Caoci S, et al. Zinc supplementation reduces morbidity and mortality in very-low birth-weight preterm neonates: a hospital-based randomized, placebo-controlled trial in an industrialized country. Am J Clin Nutr. 2013;98:1468–74.
pubmed: 24025633
Friel JK, Andrews WL, Matthew JS, Long DR, Cornel AM, Cox M. et al. Zinc supplementation in very-low-birth-weight infants. J Pediatr Gastroenterol Nutr. 1993;17:97–104.
pubmed: 8350219
Wauben IP, Atkinson SA, Grad TL, Shah JK, Paes B. Moderate nutrient supplementation of mother’s milk for preterm infants supports adequate bone mass and short-term growth: a randomized, controlled trial. Am J Clin Nutr. 1998;67:465–72.
pubmed: 9497191
Kumar TVR, Ramji S. Effect of zinc supplementation on growth in very low birth weight infants. J Tropical Pediatr. 2012;58:50–4.
Castillo-Durán C, Rodríguez A, Venegas G, Alvarez P, Stat GI. Zinc supplementation and growth of infants of born small for gestational age. J Pediatr. 1995;127:206–11.
pubmed: 7636643
Sandstead HH. Subclinical zinc deficiency impairs human brain function. J Trace Elem Med Biol. 2012;26:70–3.
pubmed: 22673824
Harris T, Gardner F, Podany A, Kelleher SL, Doheny KK. Increased early enteral zinc intake improves weight gain in hospitalised preterm infants. Acta Paediatr. 2019;108:1978–84.
pubmed: 31033040
Vázquez-Gomis R, Bosch-Gimenez V, Juste-Ruiz M, Vázquez-Gomis C, Izquierdo-Fos I, Pastor-Rosado J. Zinc concentration in preterm newborns at term age, a prospective observational study. BMJ Paediatr Open 2019;3:e000527.
pubmed: 31646195
pmcid: 6782045
Cousins RJ. Absorption, transport, and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin. Physiol Rev. 1985;65:238–309.
pubmed: 3885271
Terrin G. Nutritional intake influences zinc levels in preterm newborns: an observational study. Nutrients. 2020;19:E529.