IgG4-related lung disease progressing to respiratory failure.
Aortitis
IgG4‐related lung disease
corticosteroid
respiratory failure
reversibility
Journal
Respirology case reports
ISSN: 2051-3380
Titre abrégé: Respirol Case Rep
Pays: United States
ID NLM: 101631052
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
25
06
2020
revised:
11
07
2020
accepted:
27
07
2020
entrez:
14
8
2020
pubmed:
14
8
2020
medline:
14
8
2020
Statut:
epublish
Résumé
Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a systemic immune-mediated, fibroinflammatory disorder categorized as proliferative or fibrotic depending on the responsiveness of corticosteroid treatment. IgG4-related lung disease (IgG4-RLD) accounts for 13-14% of IgG4-RD cases, but respiratory failure is quite rare. A 71-year-old man diagnosed with interstitial lung disease was referred to our department after a 10-month observational period. He presented with respiratory failure at the first visit, with significant elevations in serum IgG4 levels and histopathological findings meeting the criteria of IgG4-positive plasma cells and IgG4/IgG-positive plasma cell ratio in transbronchial lung biopsy and inguinal lymph node biopsy, resulting in a diagnosis of IgG4-RD. Systemic corticosteroid treatment promptly ameliorated the respiratory failure.
Identifiants
pubmed: 32789018
doi: 10.1002/rcr2.641
pii: RCR2641
pmc: PMC7418099
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e00641Informations de copyright
© 2020 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology.
Références
Rheumatology (Oxford). 2013 Apr;52(4):679-83
pubmed: 23258649
Arthritis Rheumatol. 2015 Sep;67(9):2466-75
pubmed: 25988916
Eur J Nucl Med Mol Imaging. 2009 Jul;36(7):1121-30
pubmed: 19247654
Am J Surg Pathol. 2010 Dec;34(12):1812-9
pubmed: 21107087
Ann Am Thorac Soc. 2014 Nov;11(9):1466-75
pubmed: 25422997
J Gastroenterol. 2009;44(7):726-32
pubmed: 19396390
Kidney Int. 2013 Oct;84(4):826-33
pubmed: 23698232
Mod Rheumatol. 2012 Nov;22(6):859-70
pubmed: 22262474
Eur Respir J. 2012 Jan;39(1):180-6
pubmed: 21719489
Gut. 2007 Dec;56(12):1719-24
pubmed: 17525092
Mod Rheumatol. 2012 Feb;22(1):1-14
pubmed: 21881964
Am J Respir Crit Care Med. 2013 Sep 1;188(5):527-9
pubmed: 23992587
Medicine (Baltimore). 2015 Apr;94(15):e680
pubmed: 25881845
Mod Rheumatol. 2012 Feb;22(1):21-30
pubmed: 22218969
Kidney Res Clin Pract. 2019 Mar 31;38(1):42-48
pubmed: 30754935
Ann Rheum Dis. 2020 Jan;79(1):77-87
pubmed: 31796497
Eur J Nucl Med Mol Imaging. 2014 Aug;41(8):1624-34
pubmed: 24764034
Arthritis Res Ther. 2014 Jul 23;16(4):R156
pubmed: 25056443
Rheumatology (Oxford). 2005 Oct;44(10):1322-3
pubmed: 16105910
Am J Surg Pathol. 2009 Dec;33(12):1886-93
pubmed: 19898222