Metatranscriptomic Analysis Reveals Active Bacterial Communities in Diabetic Foot Infections.
RNA sequencing
active bacterial community
diabetic foot infection
metatranscriptomics
resistome
virulence factors
Journal
Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977
Informations de publication
Date de publication:
2020
2020
Historique:
received:
22
05
2020
accepted:
29
06
2020
entrez:
15
8
2020
pubmed:
15
8
2020
medline:
15
8
2020
Statut:
epublish
Résumé
Despite the extended view of the composition of diabetic foot infections (DFIs), little is known about which transcriptionally active bacterial communities are pertinent to infection, and if any differences are associated with increased infection severity. We applied a RNA sequencing approach to analyze the composition, function, and pathogenicity of the active bacterial communities in DFIs. Taxonomic profiling of bacterial transcripts revealed the presence of 14 bacterial phyla in DFIs. The abundance of the
Identifiants
pubmed: 32793159
doi: 10.3389/fmicb.2020.01688
pmc: PMC7387423
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1688Informations de copyright
Copyright © 2020 Heravi, Zakrzewski, Vickery, Malone and Hu.
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