Review on the Cellular Mechanisms of Low-Level Laser Therapy Use in Oncology.
cellular mechanism
inflammation
low-level laser therapy
metabolism
oncology
oncology treatment side effects
photobiomodulation
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2020
2020
Historique:
received:
09
04
2020
accepted:
17
06
2020
entrez:
15
8
2020
pubmed:
15
8
2020
medline:
15
8
2020
Statut:
epublish
Résumé
Photobiomodulation (PBM) using low-level laser therapy (LLLT) is a treatment that is increasingly used in oncology. Studies reported enhancement of wound healing with reduction in pain, tissue swelling and inflammatory conditions such as radiation dermatitis, oral mucositis, and lymphedema. However, factors such as wavelength, energy density and irradiation frequency influence the cellular mechanisms of LLLT. Moreover, the effects of LLLT vary according to cell types. Thus, controversy arose as a result of poor clinical response reported in some studies that may have used inadequately planned treatment protocols. Since LLLT may enhance tumor cell proliferation, these will also need to be considered before clinical use. This review aims to summarize the current knowledge of the cellular mechanisms of LLLT by considering its effects on cell proliferation, metabolism, angiogenesis, apoptosis and inflammation. With a better understanding of the cellular mechanisms, bridging findings from laboratory studies to clinical application can be improved.
Identifiants
pubmed: 32793501
doi: 10.3389/fonc.2020.01255
pmc: PMC7393265
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1255Informations de copyright
Copyright © 2020 Tam, Tam, Ramkumar, Khaw, Law and Lee.
Références
Cancer Manag Res. 2018 Dec 21;11:167-177
pubmed: 30613164
Lasers Med Sci. 2019 Dec;34(9):1917-1924
pubmed: 31267320
Photomed Laser Surg. 2005 Apr;23(2):161-6
pubmed: 15910179
Lasers Med Sci. 2018 Apr;33(3):469-477
pubmed: 29116611
Support Care Cancer. 2016 Jun;24(6):2497-501
pubmed: 26670917
Lasers Med Sci. 2012 Mar;27(2):423-30
pubmed: 21597948
J Biophotonics. 2016 Dec;9(11-12):1157-1166
pubmed: 27322660
Lasers Med Sci. 2013 Feb;28(2):367-74
pubmed: 22314560
Ann Biomed Eng. 2012 Feb;40(2):516-33
pubmed: 22045511
J Cutan Med Surg. 2013 Jan-Feb;17(1):6-12
pubmed: 23364144
J Biol Chem. 2003 Oct 17;278(42):40917-22
pubmed: 12851407
Lasers Surg Med. 2007 Apr;39(4):373-8
pubmed: 17457844
Photochem Photobiol Sci. 2002 Aug;1(8):547-52
pubmed: 12659495
Photochem Photobiol. 2019 Jan;95(1):455-459
pubmed: 30281800
J Cell Physiol. 2008 Nov;217(2):518-28
pubmed: 18615581
Lasers Surg Med. 2002;31(4):263-7
pubmed: 12355572
Lasers Med Sci. 2016 Dec;31(9):1855-1862
pubmed: 27638147
J Photochem Photobiol B. 2015 Dec;153:344-51
pubmed: 26519828
Support Care Cancer. 2012 Mar;20(3):523-9
pubmed: 21340656
Photochem Photobiol. 2009 Jul-Aug;85(4):987-96
pubmed: 19222797
Photomed Laser Surg. 2012 Mar;30(3):149-54
pubmed: 22235971
Int J Mol Sci. 2018 Jun 19;19(6):
pubmed: 29921749
Lasers Med Sci. 2013 Feb;28(2):457-63
pubmed: 22447404
Toxicol Pathol. 2007 Jun;35(4):495-516
pubmed: 17562483
Sci Rep. 2018 Nov 20;8(1):17080
pubmed: 30459437
J Invest Dermatol. 2007 May;127(5):998-1008
pubmed: 17435785
Photomed Laser Surg. 2015 Sep;33(9):452-9
pubmed: 26332916
Photomed Laser Surg. 2006 Dec;24(6):705-14
pubmed: 17199470
Lasers Med Sci. 2018 Feb;33(2):279-286
pubmed: 29098460
Front Oncol. 2018 Aug 28;8:343
pubmed: 30211121
Photomed Laser Surg. 2018 May;36(5):241-245
pubmed: 29466089
J Clin Periodontol. 2003 Apr;30(4):353-8
pubmed: 12694435
Adv Neonatal Care. 2006 Dec;6(6):303-12
pubmed: 17208161
Aust J Physiother. 1993;39(2):95-9
pubmed: 25026134
Support Care Cancer. 2016 Jun;24(6):2793-805
pubmed: 26984249
Photomed Laser Surg. 2008 Aug;26(4):401-4
pubmed: 18754721
Support Care Cancer. 2016 Jun;24(6):2781-92
pubmed: 26984240
Vasc Health Risk Manag. 2006;2(3):213-9
pubmed: 17326328
Cell Prolif. 2018 Apr;51(2):e12417
pubmed: 29160001
Ann Transl Med. 2019 Mar;7(Suppl 1):S13
pubmed: 31032294
Oxid Med Cell Longev. 2018 Nov 11;2018:6510159
pubmed: 30534349
IUBMB Life. 2010 Aug;62(8):607-10
pubmed: 20681024
Laser Ther. 2012 Dec 26;21(4):269-74
pubmed: 24511196
Photomed Laser Surg. 2005 Dec;23(6):586-9
pubmed: 16356152
Photomed Laser Surg. 2006 Feb;24(1):33-7
pubmed: 16503786
Photomed Laser Surg. 2016 Jun;34(6):229-35
pubmed: 27078192
Oral Oncol. 2016 Mar;54:7-14
pubmed: 26852286
Support Care Cancer. 2012 Nov;20(11):2977-84
pubmed: 22875413
Biochem Soc Symp. 2006;(73):165-80
pubmed: 16626297
Lasers Surg Med. 2008 Aug;40(6):433-8
pubmed: 18649378
Lasers Med Sci. 2019 Apr;34(3):629-636
pubmed: 30232646
Curr Opin Oncol. 2018 Jul;30(4):226-232
pubmed: 29794809
Dose Response. 2011;9(4):602-18
pubmed: 22461763
Lasers Med Sci. 2020 Apr 17;:
pubmed: 32304000
J Biophotonics. 2019 Oct;12(10):e201900043
pubmed: 31219220
Photochem Photobiol Sci. 2019 Jul 10;18(7):1621-1637
pubmed: 31197302
Lasers Surg Med. 2018 Oct;50(8):859-882
pubmed: 29665018
Lasers Med Sci. 2012 Jan;27(1):71-8
pubmed: 21484455
J Biomed Opt. 2015 Oct;20(10):108002
pubmed: 26502234
PLoS One. 2011;6(7):e22453
pubmed: 21814580
Photomed Laser Surg. 2010 Aug;28 Suppl 1:S151-6
pubmed: 19764894
J Photochem Photobiol B. 2013 Aug 5;125:164-70
pubmed: 23831843
Lasers Med Sci. 2019 Sep;34(7):1333-1343
pubmed: 30712124
Lasers Med Sci. 2020 Mar;35(2):337-343
pubmed: 31152259
AIMS Biophys. 2017;4(3):337-361
pubmed: 28748217