A Theoretical and Experimental Study to Optimize Cell Differentiation in a Novel Intestinal Chip.

3D printing cell differentiation gut-on-chip numerical computation shear stress

Journal

Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513

Informations de publication

Date de publication:
2020
Historique:
received: 15 03 2020
accepted: 16 06 2020
entrez: 15 8 2020
pubmed: 15 8 2020
medline: 15 8 2020
Statut: epublish

Résumé

Microphysiological systems have potential as test systems in studying the intestinal barrier, in which shear stress is critical for the differentiation of Caco-2 cells into enterocytes. The most commonly used

Identifiants

pubmed: 32793567
doi: 10.3389/fbioe.2020.00763
pmc: PMC7393935
doi:

Types de publication

Journal Article

Langues

eng

Pagination

763

Informations de copyright

Copyright © 2020 Langerak, Ahmed, Li, Middel, Eslami Amirabadi, Malda, Masereeuw and van Roij.

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Auteurs

Nicky Langerak (N)

Institute for Theoretical Physics, Utrecht University, Utrecht, Netherlands.

Haysam M M Ahmed (HMM)

Division of Pharmacology, Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.

Yang Li (Y)

Utrecht Biofabrication Facility, University Medical Center Utrecht, Utrecht, Netherlands.

Igor R Middel (IR)

Division of Pharmacology, Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.

Hossein Eslami Amirabadi (H)

Division of Pharmacology, Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.
Human Cell Biology Group, Division of Metabolic Health Research, TNO, Zeist, Netherlands.

Jos Malda (J)

Utrecht Biofabrication Facility, University Medical Center Utrecht, Utrecht, Netherlands.

Rosalinde Masereeuw (R)

Division of Pharmacology, Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.

René van Roij (R)

Institute for Theoretical Physics, Utrecht University, Utrecht, Netherlands.

Classifications MeSH