Abiotrophia defectiva liver abscess in a teenage boy after a supposedly mild blunt abdominal trauma: a case report.
Abiotrophia defectiva
Case report
Children
Liver abscess
Liver trauma
Journal
BMC gastroenterology
ISSN: 1471-230X
Titre abrégé: BMC Gastroenterol
Pays: England
ID NLM: 100968547
Informations de publication
Date de publication:
14 Aug 2020
14 Aug 2020
Historique:
received:
17
12
2019
accepted:
03
08
2020
entrez:
16
8
2020
pubmed:
17
8
2020
medline:
15
5
2021
Statut:
epublish
Résumé
A pyogenic liver abscess (PLA) represents a pus-filled cavity within the liver parenchyma caused by the invasion and multiplication of bacteria. The most common offender isolated from the PLA in children is Staphylococcus aureus. Abiotrophia defectiva is a Gram-positive pleomorphic bacterium, commonly found in the oral cavity, intestinal, and genitourinary mucosa as part of the normal microbiota. It has been proven to be an etiological factor in various infections, but rarely in cases of PLA. The case presented here is, to the best of our knowledge, the first pediatric case of PLA caused by A. defectiva. A 13-year-old Caucasian boy presented with a two-day history of abdominal pain, fever up to 40 °C, and polyuria. Contrast-enhanced computed tomography (CT) scan revealed a single, multiloculated liver lesion, suggestive of a liver abscess. The boy had sustained a bicycle handlebar injury to his upper abdomen 3 weeks before the symptoms appeared and had been completely asymptomatic until 2 days before admission. He was successfully treated with antibiotic therapy and open surgical drainage. A. defectiva was isolated from the abscess material. Histopathology report described the lesion as a chronic PLA. A. defectiva is a highly uncommon cause of liver abscess in children. In such cases, various predisposing factors should be considered, including antecedent blunt abdominal trauma.
Sections du résumé
BACKGROUND
BACKGROUND
A pyogenic liver abscess (PLA) represents a pus-filled cavity within the liver parenchyma caused by the invasion and multiplication of bacteria. The most common offender isolated from the PLA in children is Staphylococcus aureus. Abiotrophia defectiva is a Gram-positive pleomorphic bacterium, commonly found in the oral cavity, intestinal, and genitourinary mucosa as part of the normal microbiota. It has been proven to be an etiological factor in various infections, but rarely in cases of PLA. The case presented here is, to the best of our knowledge, the first pediatric case of PLA caused by A. defectiva.
CASE PRESENTATION
METHODS
A 13-year-old Caucasian boy presented with a two-day history of abdominal pain, fever up to 40 °C, and polyuria. Contrast-enhanced computed tomography (CT) scan revealed a single, multiloculated liver lesion, suggestive of a liver abscess. The boy had sustained a bicycle handlebar injury to his upper abdomen 3 weeks before the symptoms appeared and had been completely asymptomatic until 2 days before admission. He was successfully treated with antibiotic therapy and open surgical drainage. A. defectiva was isolated from the abscess material. Histopathology report described the lesion as a chronic PLA.
CONCLUSIONS
CONCLUSIONS
A. defectiva is a highly uncommon cause of liver abscess in children. In such cases, various predisposing factors should be considered, including antecedent blunt abdominal trauma.
Identifiants
pubmed: 32795255
doi: 10.1186/s12876-020-01409-6
pii: 10.1186/s12876-020-01409-6
pmc: PMC7427900
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
267Références
J Med Microbiol. 2002 Oct;51(10):899-902
pubmed: 12435072
Can J Kidney Health Dis. 2016 Dec 05;3:2054358116678206
pubmed: 28270927
Clin Liver Dis (Hoboken). 2015 Aug 24;6(2):51-54
pubmed: 31040988
Am J Trop Med Hyg. 2016 Jan;94(1):147-55
pubmed: 26572872
Indian J Pediatr. 2006 Sep;73(9):813-7
pubmed: 17006041
Ann Surg. 1996 May;223(5):600-7; discussion 607-9
pubmed: 8651751
J Visc Surg. 2015 Sep;152(4):231-43
pubmed: 25770745
HPB (Oxford). 2017 Oct;19(10):889-893
pubmed: 28693978
Antimicrob Agents Chemother. 2015 Dec 14;60(3):1411-20
pubmed: 26666926
Ann Surg. 1991 Jun;213(6):540-7; discussion 548
pubmed: 2039284
Langenbecks Arch Surg. 2003 Jan;387(9-10):343-7
pubmed: 12536329
World J Pediatr. 2010 Aug;6(3):210-6
pubmed: 20706820
World J Gastroenterol. 2010 May 28;16(20):2458-62
pubmed: 20503444
Korean J Intern Med. 1999 Jan;14(1):73-6
pubmed: 10063317
Int J Syst Evol Microbiol. 2000 Jan;50 Pt 1:365-369
pubmed: 10826824
J Trauma. 1995 Mar;38(3):323-4
pubmed: 7897707
Clin Infect Dis. 2004 Dec 1;39(11):1654-9
pubmed: 15578367
J Glob Infect Dis. 2017 Apr-Jun;9(2):79-81
pubmed: 28584461