Early epitope-specific IgE antibodies are predictive of childhood peanut allergy.

Adolescent Algorithms Allergens / immunology Arachis / immunology Child Child, Preschool Cohort Studies Epitopes / immunology Female Follow-Up Studies Humans Immune Tolerance Immunoglobulin E / metabolism Immunoglobulin G / metabolism Infant Machine Learning Male Peanut Hypersensitivity / diagnosis Precision Medicine Predictive Value of Tests Prognosis Prospective Studies
Ara h 1 Ara h 2 Ara h 3 Bead-Based Epitope Assay IgE IgG(4) Peanut allergy antibodies epitopes machine learning precision medicine

Journal

The Journal of allergy and clinical immunology
ISSN: 1097-6825
Titre abrégé: J Allergy Clin Immunol
Pays: United States
ID NLM: 1275002

Informations de publication

Date de publication:
11 2020
Historique:
received: 12 05 2020
revised: 31 07 2020
accepted: 05 08 2020
pubmed: 17 8 2020
medline: 16 3 2021
entrez: 16 8 2020
Statut: ppublish

Résumé

Peanut allergy is characterized by the development of IgE against peanut antigen. We sought to evaluate the evolution of epitope-specific (es)IgE and esIgG The end point was allergy status at age 4 At age 4 Early epitope-specific plus peanut-specific IgE is predictive of allergy status at age 4

Sections du résumé

BACKGROUND
Peanut allergy is characterized by the development of IgE against peanut antigen.
OBJECTIVE
We sought to evaluate the evolution of epitope-specific (es)IgE and esIgG
METHODS
The end point was allergy status at age 4
RESULTS
At age 4
CONCLUSIONS
Early epitope-specific plus peanut-specific IgE is predictive of allergy status at age 4

Identifiants

DOI: 10.1016/j.jaci.2020.08.005 PMID: 32795587 PMC: PMC8095129
pubmed: 32795587
pii: S0091-6749(20)31111-8
doi: 10.1016/j.jaci.2020.08.005
pmc: PMC8095129
mid: NIHMS1620464
pii:
doi:

Substances chimiques

Allergens 0
Epitopes 0
Immunoglobulin G 0
Immunoglobulin E 37341-29-0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1080-1088

Subventions

Organisme : NIAID NIH HHS
ID : U01 AI066560
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR003107
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI066738
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000083
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002535
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM062754
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000424
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000067
Pays : United States

Informations de copyright

Copyright © 2020 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Références

J Allergy Clin Immunol. 2008 Mar;121(3):737-743.e10
pubmed: 18234310
Int Arch Allergy Immunol. 2016;169(4):216-22
pubmed: 27225199
Pediatrics. 2019 Mar;143(3):
pubmed: 30819972
Biostatistics. 2013 Jan;14(1):87-98
pubmed: 22926914
Clin Exp Allergy. 2004 Apr;34(4):583-90
pubmed: 15080811
J Allergy Clin Immunol. 2008 Jul;122(1):145-51
pubmed: 18502490
Immunol Rev. 2015 Nov;268(1):139-59
pubmed: 26497518
J Allergy Clin Immunol Pract. 2013 Nov-Dec;1(6):632-8.e1
pubmed: 24565711
J Allergy Clin Immunol. 2004 Apr;113(4):776-82
pubmed: 15100687
Bioinformatics. 2019 May 1;35(9):1605-1607
pubmed: 30304481
Allergy. 2019 Nov;74(11):2199-2211
pubmed: 31120555
Biometrics. 1988 Sep;44(3):837-45
pubmed: 3203132
Eur J Biochem. 1997 Apr 15;245(2):334-9
pubmed: 9151961
J Allergy Clin Immunol. 2012 Apr;129(4):1056-63
pubmed: 22385632
Biostatistics. 2007 Jan;8(1):118-27
pubmed: 16632515
J Allergy Clin Immunol. 2011 Jan;127(1):18-27; quiz 28-9
pubmed: 21211639
J Allergy Clin Immunol. 2014 Sep;134(3):753-5
pubmed: 25086866
J Allergy Clin Immunol Pract. 2016 Mar-Apr;4(2):239-45.e4
pubmed: 26718150
Immunol Rev. 2007 Jun;217:206-21
pubmed: 17498061
J Allergy Clin Immunol. 2015 Apr;135(4):913-921.e9
pubmed: 25457150
J Allergy Clin Immunol. 2005 Oct;116(4):893-9
pubmed: 16210066
Nucleic Acids Res. 2015 Apr 20;43(7):e47
pubmed: 25605792
J Allergy Clin Immunol. 2004 Jul;114(1):144-9
pubmed: 15241358
Clin Exp Allergy. 2015 Feb;45(2):471-84
pubmed: 25213872
Science. 2007 Sep 14;317(5844):1554-7
pubmed: 17872445
J Allergy Clin Immunol. 2011 Mar;127(3):603-7
pubmed: 21093026
J Allergy Clin Immunol. 2007 Apr;119(4):1016-8
pubmed: 17306354
J Allergy Clin Immunol. 2015 May;135(5):1257-66.e1-2
pubmed: 25725989
Clin Exp Allergy. 2015 Apr;45(4):720-30
pubmed: 25226880
Allergy. 2014 Apr;69(4):413-9
pubmed: 24738154
J Allergy Clin Immunol. 2014 Nov;134(5):1016-25.e43
pubmed: 25174862
Mol Immunol. 2018 Aug;100:58-70
pubmed: 29680589
Allergy. 2020 Sep;75(9):2309-2318
pubmed: 32248566
Arch Biochem Biophys. 1997 Jun 15;342(2):244-53
pubmed: 9186485
J Allergy Clin Immunol. 2010 May;125(5):1077-1083.e8
pubmed: 20451041
Allergol Int. 2015 Oct;64(4):332-43
pubmed: 26433529
Mol Immunol. 2018 Aug;100:3-13
pubmed: 29625844
Pediatrics. 2011 Jul;128(1):e9-17
pubmed: 21690110
J Allergy Clin Immunol. 2001 May;107(5):891-6
pubmed: 11344358
J Allergy Clin Immunol. 2019 Mar;143(3):1038-1046
pubmed: 30528770
Sci Rep. 2019 Dec 5;9(1):18425
pubmed: 31804555
J Allergy Clin Immunol. 2016 Nov;138(5):1426-1433.e12
pubmed: 27264457
J Clin Invest. 1999 Feb;103(4):535-42
pubmed: 10021462
J Allergy Clin Immunol. 2016 Nov;138(5):1434-1435
pubmed: 27566454

Auteurs

Maria Suprun (M)

Icahn School of Medicine at Mount Sinai, New York, NY.

Scott H Sicherer (SH)

Icahn School of Medicine at Mount Sinai, New York, NY.

Robert A Wood (RA)

Johns Hopkins University School of Medicine, Baltimore, Md.

Stacie M Jones (SM)

University of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock, Ark.

Donald Y M Leung (DYM)

National Jewish Health, Denver, Colo.

Alice K Henning (AK)

Emmes, Rockville, Md.

Peter Dawson (P)

Emmes, Rockville, Md.

A Wesley Burks (AW)

University of North Carolina, Chapel Hill, NC.

Robert Lindblad (R)

Emmes, Rockville, Md.

Robert Getts (R)

AllerGenis LLC, Hatfield, Pa.

Mayte Suárez-Fariñas (M)

Icahn School of Medicine at Mount Sinai, New York, NY.

Hugh A Sampson (HA)

Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: hugh.sampson@mssm.edu.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adolescent › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Algorithmes › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Allergènes › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Fabaceae › Arachis › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Enfant d'âge préscolaire › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Épitopes › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études de suivi › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunomodulation › Tolérance immunitaire › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Isotypes des immunoglobulines › Immunoglobuline E › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Isotypes des immunoglobulines › Immunoglobuline G › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Algorithmes › Intelligence artificielle › Apprentissage machine › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Maladies du système immunitaire › Hypersensibilité › Hypersensibilité immédiate › Hypersensibilité alimentaire › Hypersensibilité aux noix et aux arachides › Hypersensibilité aux arachides › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Professions de santé › Médecine › Médecine clinique › Médecine de précision › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Valeur prédictive des tests › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Diagnostic › Pronostic › Early epitope-specific IgE antibodies are...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Early epitope-specific IgE antibodies are...