Incidental Metastatic Melanoma Identified on 18F-FDOPA PET/CT With Confirmation by Histology.
Journal
Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
pubmed:
17
8
2020
medline:
13
11
2020
entrez:
16
8
2020
Statut:
ppublish
Résumé
A 47-year-old woman with a history of surgically treated abdominal paraganglioma and left thigh melanoma underwent an F-FDOPA PET/CT for suspected locoregional recurrence of paraganglioma. F-FDOPA PET/CT disconfirmed this recurrence but revealed 2 FDOPA-avid left inguinal lymph nodes, confirmed on a subsequent F-FDG PET/CT. Excision and pathology characterized these lymph nodes as melanoma metastases. F-FDOPA PET/CT is a widely used and valuable tool in the assessment of paraganglioma, both for staging and recurrence detection. Uptake of FDOPA has only rarely been documented in metastatic melanoma that could be a pitfall for detecting neuroendocrine tumors.
Identifiants
pubmed: 32796240
doi: 10.1097/RLU.0000000000003233
pii: 00003072-202010000-00020
doi:
Substances chimiques
fluorodopa F 18
2C598205QX
Dihydroxyphenylalanine
63-84-3
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
817-818Références
Dimitrakopoulou-Strauss A, Strauss LG, Burger C. Quantitative PET studies in pretreated melanoma patients: a comparison of 6-[18F]fluoro-L-dopa with 18F-FDG and (15)O-water using compartment and noncompartment analysis. J Nucl Med. 2001;42:248–256.
Seshadri N, Wat J, Balan K. Bilateral adrenal metastases from malignant melanoma: concordant findings on 18F-FDG and 18F-FDOPA PET. Eur J Nucl Med Mol Imaging. 2006;33:854–855.
Burgers AMG, Wondergem M, van der Zant FM, et al. Incidental detection of a melanoma by 18F-fluorocholine PET/CT performed for evaluation of primary hyperparathyroidism. Clin Nucl Med. 2018;43:265–266.
Sollini M, Pasqualetti F, Perri M, et al. Detection of a second malignancy in prostate cancer patients by using [18F]choline PET/CT: a case series. Cancer Imaging. 2016;16:27.
Snow HA, Hofman MS, Mitchell CA, et al. Incidental metastatic melanoma identified on 68Ga-prostate-specific membrane antigen PET/CT for metastatic prostate cancer. Clin Nucl Med. 2018;43:509–511.
Anconina R, Hod N, Levin D, et al. Incidental detection of metastatic malignant melanoma on 68Ga-prostate-specific membrane antigen PET/CT imaging: correlative imaging with FDG PET/CT and review of the literature. Clin Nucl Med. 2018;43:204–206.
Treglia G, Cocciolillo F, de Waure C, et al. Diagnostic performance of 18F-dihydroxyphenylalanine positron emission tomography in patients with paraganglioma: a meta-analysis. Eur J Nucl Med Mol Imaging. 2012;39:1144–1153.
Bacca A, Chiacchio S, Zampa V, et al. Role of 18F-DOPA PET/CT in diagnosis and follow-up of adrenal and extra-adrenal paragangliomas. Clin Nucl Med. 2014;39:14–20.
Balogova S, Talbot JN, Nataf V, et al. 18F-fluorodihydroxyphenylalanine vs other radiopharmaceuticals for imaging neuroendocrine tumours according to their type. Eur J Nucl Med Mol Imaging. 2013;40:943–966.