Decreased Expression of
Adolescent
Adult
Aged
Brain Neoplasms
/ genetics
Cell Cycle Checkpoints
/ genetics
Cell Line, Tumor
Cell Proliferation
/ genetics
Female
Gene Expression Regulation, Neoplastic
Genome, Human
Glioma
/ genetics
Humans
Kruppel-Like Transcription Factors
/ genetics
Male
Middle Aged
RNA, Messenger
/ genetics
Signal Transduction
Survival Analysis
Young Adult
glioblastoma
glioma
survival
transcriptome
zinc finger protein
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
11 Aug 2020
11 Aug 2020
Historique:
received:
23
06
2020
revised:
31
07
2020
accepted:
05
08
2020
entrez:
16
8
2020
pubmed:
17
8
2020
medline:
18
2
2021
Statut:
epublish
Résumé
Zinc finger protein 554 (ZNF554), a member of the Krüppel-associated box domain zinc finger protein subfamily, is predominantly expressed in the brain and placenta in humans. Recently, we unveiled that ZNF554 regulates trophoblast invasion during placentation and its decreased expression leads to the early pathogenesis of preeclampsia. Since ZNF proteins are immensely implicated in the development of several tumors including malignant tumors of the brain, here we explored the pathological role of ZNF554 in gliomas.
Identifiants
pubmed: 32796700
pii: ijms21165762
doi: 10.3390/ijms21165762
pmc: PMC7461028
pii:
doi:
Substances chimiques
Kruppel-Like Transcription Factors
0
RNA, Messenger
0
ZNF554 protein, human
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Hungarian Scientific Research Fund
ID : K128262
Organisme : Hungarian Scientific Research Fund
ID : K124862
Organisme : Magyar Tudományos Akadémia
ID : Momentum LP2014-7/2014
Organisme : Magyar Tudományos Akadémia
ID : Premium_2019-436
Organisme : Magyar Tudományos Akadémia
ID : Young Research Fellowships
Organisme : Nemzeti Kutatási Fejlesztési és Innovációs Hivatal
ID : FIEK_16-1-2016-0005
Organisme : Nemzeti Kutatási Fejlesztési és Innovációs Hivatal
ID : VEKOP-2.3.3-15-2017-0014
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