Risk factors for spontaneous hematoma of the umbilical cord: A case-control study.


Journal

Placenta
ISSN: 1532-3102
Titre abrégé: Placenta
Pays: Netherlands
ID NLM: 8006349

Informations de publication

Date de publication:
15 09 2020
Historique:
received: 17 04 2020
revised: 30 06 2020
accepted: 20 07 2020
pubmed: 18 8 2020
medline: 14 8 2021
entrez: 18 8 2020
Statut: ppublish

Résumé

Spontaneous hematomas of the umbilical cord are rare and often fatal to the fetus. Little is known about their mechanism or their risk factors. In view of their rarity, the series are limited. No comparative study enabling the identification of factors associated with these hematomas has been published. This retrospective case-control study of 13 spontaneous histologically confirmed hematomas of the umbilical cord over a consecutive 16-year period compared the characteristics of the case mothers and fetuses to those of a group of 39 control mothers who gave birth the same day as the case mothers. In utero death was high in the case group (46.2% vs 0.0%, P < 0.001). Third-trimester oligohydramnios (30.8 vs 2.6%, OR = 16.9, P = 0.01), second-trimester amniocentesis (33.3 vs 5.1%, OR = 9.3, P = 0.02), and a reduction in fetal movements as perceived by the mother (35.7 vs 7.7%, P = 0.02) were significantly associated with spontaneous umbilical cord hematomas. Third-trimester oligohydramnios and second-trimester amniocentesis appear to be associated with the occurrence of a spontaneous hematoma of the umbilical cord.

Sections du résumé

BACKGROUND
Spontaneous hematomas of the umbilical cord are rare and often fatal to the fetus. Little is known about their mechanism or their risk factors. In view of their rarity, the series are limited. No comparative study enabling the identification of factors associated with these hematomas has been published.
MATERIAL AND METHODS
This retrospective case-control study of 13 spontaneous histologically confirmed hematomas of the umbilical cord over a consecutive 16-year period compared the characteristics of the case mothers and fetuses to those of a group of 39 control mothers who gave birth the same day as the case mothers.
RESULTS
In utero death was high in the case group (46.2% vs 0.0%, P < 0.001). Third-trimester oligohydramnios (30.8 vs 2.6%, OR = 16.9, P = 0.01), second-trimester amniocentesis (33.3 vs 5.1%, OR = 9.3, P = 0.02), and a reduction in fetal movements as perceived by the mother (35.7 vs 7.7%, P = 0.02) were significantly associated with spontaneous umbilical cord hematomas.
CONCLUSION
Third-trimester oligohydramnios and second-trimester amniocentesis appear to be associated with the occurrence of a spontaneous hematoma of the umbilical cord.

Identifiants

pubmed: 32798767
pii: S0143-4004(20)30210-1
doi: 10.1016/j.placenta.2020.07.020
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

152-156

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Yasmine Clermont-Hama (Y)

Pôle Femme Mère Nouveau-né, Hôpital Jeanne de Flandre, Université Lille Nord de France, 1 rue Eugène Avinée, 59037, Lille Cedex, France. Electronic address: yclermonthama@gmail.com.

Kathleen Thibouw (K)

Pôle Femme Mère Nouveau-né, Hôpital Jeanne de Flandre, Université Lille Nord de France, 1 rue Eugène Avinée, 59037, Lille Cedex, France.

Louise Devisme (L)

Pôle de Pathologie, Centre de Biologie-Pathologie, CHRU de Lille, 1 rue Eugène Avinée, 59037, Lille Cedex, France.

Hélène Franquet-Ansart (H)

Pôle de Pathologie, Centre de Biologie-Pathologie, CHRU de Lille, 1 rue Eugène Avinée, 59037, Lille Cedex, France.

Morgane Stichelbout (M)

Pôle de Pathologie, Centre de Biologie-Pathologie, CHRU de Lille, 1 rue Eugène Avinée, 59037, Lille Cedex, France.

Damien Subtil (D)

Pôle Femme Mère Nouveau-né, Hôpital Jeanne de Flandre, Université Lille Nord de France, 1 rue Eugène Avinée, 59037, Lille Cedex, France; EA 2694, PRES Université Lille Nord de France, F-59000, Lille, France.

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Classifications MeSH