Current Status of Laboratory Diagnosis for COVID-19: A Narrative Review.
COVID-19
PCR
SARS-CoV-2
laboratory diagnosis
serological test
Journal
Infection and drug resistance
ISSN: 1178-6973
Titre abrégé: Infect Drug Resist
Pays: New Zealand
ID NLM: 101550216
Informations de publication
Date de publication:
2020
2020
Historique:
received:
22
05
2020
accepted:
05
07
2020
entrez:
18
8
2020
pubmed:
18
8
2020
medline:
18
8
2020
Statut:
epublish
Résumé
The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the related disease (COVID-19) has spread rapidly to pandemic proportions, increasing the demands on healthcare systems for the containment and management of COVID-19. One of the critical issues to be addressed is the improvement in laboratory diagnosis and screening of large portions of the population to stop the virus spreading. Currently, the laboratory diagnosis of SARS-CoV-2 infection and the related disease is based on the research of viral RNA with rt-PCR methods in upper and lower respiratory airways. Serological tests to detect SARS-CoV-2 antibodies could help physicians and healthcare workers to support COVID-19 diagnosis and follow-up and perform population screening. Our review, using MEDLINE and EMBASE, summarizes the current knowledge of direct and serological tests performed to research RNA, antigens, or antibodies for SARS-CoV-2, evaluating the advantages and drawbacks for specific tests.
Identifiants
pubmed: 32801804
doi: 10.2147/IDR.S264020
pii: 264020
pmc: PMC7413717
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
2657-2665Informations de copyright
© 2020 Russo et al.
Déclaration de conflit d'intérêts
The authors report no funding and no conflicts of interest for this work.
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