Lifestyle and reproductive health: the aetiology of ovarian cancer in Pakistan.
Lifestyle
Miscarriage
Ovarian Cancer
Pakistan
Reproductive Health
Journal
F1000Research
ISSN: 2046-1402
Titre abrégé: F1000Res
Pays: England
ID NLM: 101594320
Informations de publication
Date de publication:
2020
2020
Historique:
accepted:
23
07
2020
entrez:
18
8
2020
pubmed:
18
8
2020
medline:
28
4
2021
Statut:
epublish
Résumé
Ovarian cancer is a fatal gynaecological cancer and eighth most common cancer in women globally. Lifestyle, reproductive and sociodemographic factors are among the influential parameters that may significantly affect the risk of ovarian cancer and its mortality rate. However, the epidemiological investigations have shown that the risk of ovarian cancers associated with these factors is different in varied geographical distributions. Lifestyle and reproductive factors have not been investigated thoroughly across a wide cultural diversity. The objective of this study is to investigate the association of these factors with ovarian cancer in Pakistan. This investigation will focus on the lifestyle effects of fat intake, intake of tea, habitual exercise, use of talc, personal hygiene, habit of holding urine for long time, obesity on ovarian cancer among Pakistani women. Reproductive variables will include age at menarche, natural menopausal age, parity, nulliparity (miscarriages, abortion, stillbirths), infertility, fertility treatment, tubal ligation, oral contraceptive use, and family history of breast or ovarian cancer. Sociodemographic variables will include effect of age, income, education, and geographical location. A case-control study will be conducted in the major cancer hospitals of Pakistan and the patients will also be interviewed. The controls will be recruited outside the hospital. For controls the same age limit and residency requirements will be applied. The information gained from this research will be an important contribution to develop programs for health promotion, with a focus on ovarian cancer prevention and women's health. The findings could be used for health policies and planning to prevent ovarian cancer. The research will pave the way for a public policy and interventions to reduce the burden of ovarian cancer in Pakistan.
Identifiants
pubmed: 32802322
doi: 10.12688/f1000research.24866.1
pmc: PMC7417955
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
901Informations de copyright
Copyright: © 2020 Alvi Q et al.
Déclaration de conflit d'intérêts
No competing interests were disclosed.
Références
Ann Oncol. 2017 Apr 1;28(4):727-732
pubmed: 27993805
Gynecol Oncol. 2017 Mar;144(3):571-576
pubmed: 28108026
Psychooncology. 2019 Feb;28(2):379-385
pubmed: 30485590
CA Cancer J Clin. 2018 Jul;68(4):284-296
pubmed: 29809280
Curr Pharmacol Rep. 2018;4(3):250-260
pubmed: 30363743
Br J Cancer. 2015 Mar 31;112(7):1257-65
pubmed: 25742479
Int J Womens Health. 2019 Apr 30;11:287-299
pubmed: 31118829
Recent Results Cancer Res. 2016;208:155-176
pubmed: 27909907
Int J Cancer. 2017 Jan 15;140(2):285-291
pubmed: 27667654
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Lancet Oncol. 2018 Aug;19(8):1107-1116
pubmed: 30029888
Cancer Epidemiol Biomarkers Prev. 2019 Nov;28(11):1835-1844
pubmed: 31455671
Cancer Causes Control. 2017 May;28(5):393-403
pubmed: 28102526
Clin Obstet Gynecol. 2012 Mar;55(1):3-23
pubmed: 22343225
Biochem Soc Trans. 2019 Feb 28;47(1):295-304
pubmed: 30700499
Cancer Epidemiol Biomarkers Prev. 2013 Mar;22(3):429-37
pubmed: 23307531
Lancet. 2014 Oct 11;384(9951):1376-88
pubmed: 24767708
Cancer Causes Control. 2019 Sep;30(9):967-978
pubmed: 31236792
Cancer Epidemiol. 2013 Feb;37(1):54-9
pubmed: 23107758
Rev Bras Ginecol Obstet. 2017 Dec;39(12):676-685
pubmed: 29179244
Cancer Med. 2016 Jun;5(6):1319-27
pubmed: 26923432
JAMA Oncol. 2016 Sep 1;2(9):1154-61
pubmed: 27196525
J Natl Cancer Inst. 2017 Oct 1;109(10):
pubmed: 29117355
Int J Cancer. 2017 Jun 1;140(11):2451-2460
pubmed: 28257597
Best Pract Res Clin Obstet Gynaecol. 2017 May;41:3-14
pubmed: 27743768
Curr Cancer Drug Targets. 2018;18(6):522-537
pubmed: 29295697
Ann Epidemiol. 2016 Sep;26(9):654-62
pubmed: 27528178