A New MEN2 Syndrome with Clinical Features of Both MEN2A and MEN2B Associated with a New


Journal

Case reports in endocrinology
ISSN: 2090-6501
Titre abrégé: Case Rep Endocrinol
Pays: United States
ID NLM: 101576457

Informations de publication

Date de publication:
2020
Historique:
received: 14 01 2020
accepted: 25 03 2020
entrez: 18 8 2020
pubmed: 18 8 2020
medline: 18 8 2020
Statut: epublish

Résumé

Multiple endocrine neoplasia type 2 (MEN2) is a hereditary cancer syndrome caused by This is the first case of a complex syndrome characterized by peculiar features of MEN2B, without Pheo but with a pelvic plexiform neurofibroma and with HPTH, which is typical of MEN2A. A "de novo" new germline

Sections du résumé

BACKGROUND BACKGROUND
Multiple endocrine neoplasia type 2 (MEN2) is a hereditary cancer syndrome caused by
CONCLUSIONS CONCLUSIONS
This is the first case of a complex syndrome characterized by peculiar features of MEN2B, without Pheo but with a pelvic plexiform neurofibroma and with HPTH, which is typical of MEN2A. A "de novo" new germline

Identifiants

pubmed: 32802527
doi: 10.1155/2020/4147097
pmc: PMC7411486
doi:

Types de publication

Case Reports

Langues

eng

Pagination

4147097

Informations de copyright

Copyright © 2020 Carlotta Giani et al.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest regarding the publication of this article.

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Auteurs

Carlotta Giani (C)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Teresa Ramone (T)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Cristina Romei (C)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Raffaele Ciampi (R)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Alessia Tacito (A)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Laura Valerio (L)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Laura Agate (L)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Clara Ugolini (C)

Pathology Unit, Department of Surgical and Medical Pathology, University Hospital of Pisa, 56124 Pisa, Italy.

Michele Marinò (M)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Fulvio Basolo (F)

Pathology Unit, Department of Surgical and Medical Pathology, University Hospital of Pisa, 56124 Pisa, Italy.

Alessandro Franchi (A)

Pathology Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University Hospital of Pisa, 56124 Pisa, Italy.

Simona Borsari (S)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Angela Michelucci (A)

Unit of Molecular Genetics, Department of Laboratory Medicine, University Hospital of Pisa, 56126 Pisa, Italy.

Cesare Selli (C)

Division of Urology, Department of Translational Research and New Technologies in Medicine and Surgery, University Hospital of Pisa, 56124 Pisa, Italy.

Gabriele Materazzi (G)

Surgery Unit, Department of Surgical and Medical Pathology, University Hospital of Pisa, 56124 Pisa, Italy.

Filomena Cetani (F)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Rossella Elisei (R)

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Classifications MeSH