Differential diagnosis of orthostatic hypotension.
Delayed orthostatic hypotension
Initial orthostatic hypotension
Neurogenic orthostatic hypotension
Orthostatic hypotension
Postural orthostatic tachycardia syndrome
Vasovagal syncope
Journal
Autonomic neuroscience : basic & clinical
ISSN: 1872-7484
Titre abrégé: Auton Neurosci
Pays: Netherlands
ID NLM: 100909359
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
09
03
2020
revised:
07
06
2020
accepted:
27
07
2020
pubmed:
18
8
2020
medline:
23
9
2021
entrez:
18
8
2020
Statut:
ppublish
Résumé
Orthostatic hypotension (OH) is a common clinical manifestation characterized by a significant fall in blood pressure with postural change and is frequently accompanied by debilitating symptoms of orthostatic intolerance. The reported prevalence of OH ranges between 5 and 10% in middle-aged adults with a burden that increases concomitantly with age; in those over 60 years of age, the prevalence is estimated to be over 20%. Unfortunately, the clinical course of OH is not necessarily benign. OH patients are at an increased risk of adverse clinical outcomes including death, falls, cardiovascular and cerebrovascular events, syncope, and impaired quality of life. The differential diagnosis of OH is broad and includes acute precipitants as well as chronic underlying medical conditions, especially of neurological origin. Appropriate diagnosis relies on a systematic history and physical examination with particular attention to orthostatic vital signs, keeping in mind that ambient conditions during diagnostic testing may affect OH detection due to factors such as diurnal variation.
Identifiants
pubmed: 32805514
pii: S1566-0702(20)30147-8
doi: 10.1016/j.autneu.2020.102713
pmc: PMC7502506
mid: NIHMS1620914
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
102713Subventions
Organisme : NCATS NIH HHS
ID : UL1 TR002243
Pays : United States
Organisme : CIHR
ID : MOP142426
Pays : Canada
Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest SRR is a consultant to Lundbeck LLC and Theravance Biopharma related to neurogenic orthostatic hypotension, and has received honoraria from the Academy for Continued Healthcare Learning and Medscape for developing continuing medical educational materials about neurogenic orthostatic hypotension. He also serves as DMSB Chair for a Phase 2 study of an irritable bowel syndrome medication for Arena Pharmaceuticals with compensation. SRR is currently the President of the American Autonomic Society without financial compensation.
Références
Clin Auton Res. 2001 Dec;11(6):363-7
pubmed: 11794717
Am J Med. 2007 Nov;120(11):975-80
pubmed: 17976425
Can J Cardiol. 2020 Mar;36(3):357-372
pubmed: 32145864
Clin Auton Res. 1996 Apr;6(2):111-4
pubmed: 8726096
Clin Ther. 2007 Jan;29(1):17-25
pubmed: 17379044
Mov Disord Clin Pract. 2017 May-Jun;4(3):298-308
pubmed: 28713844
J Neurol Sci. 2010 Dec 15;299(1-2):45-8
pubmed: 20855089
BMJ. 2013 Nov 05;347:f6320
pubmed: 24192967
J Intern Med. 2013 Apr;273(4):322-35
pubmed: 23216860
Semin Neurol. 2019 Apr;39(2):274-282
pubmed: 30925619
Am J Med Sci. 2000 Jul;320(1):1-8
pubmed: 10910366
J Gerontol A Biol Sci Med Sci. 2005 Oct;60(10):1268-70
pubmed: 16282557
J Am Geriatr Soc. 2017 Mar;65(3):474-482
pubmed: 28295143
J Pediatr. 2011 Mar;158(3):499-504
pubmed: 20970148
J Am Coll Cardiol. 2015 Aug 18;66(7):848-860
pubmed: 26271068
Heart Rhythm. 2015 Jun;12(6):e41-63
pubmed: 25980576
Mov Disord. 2016 Apr;31(4):598-600
pubmed: 26879239
Heart Fail Rev. 2016 Sep;21(5):529-38
pubmed: 26880254
Mov Disord. 2003 Sep;18 Suppl 6:S21-7
pubmed: 14502652
Neurology. 2006 Jul 11;67(1):28-32
pubmed: 16832073
N Engl J Med. 2008 Feb 7;358(6):615-24
pubmed: 18256396
J Am Med Dir Assoc. 2014 Jun;15(6):394-409
pubmed: 24630686
Br J Urol. 1997 Oct;80(4):597-605
pubmed: 9352699
Circulation. 2000 Feb 1;101(4):398-402
pubmed: 10653831
Clin Auton Res. 2017 Jul;27(Suppl 1):39-43
pubmed: 28620715
Hypertension. 2005 Apr;45(4):469-76
pubmed: 15738343
Clin Auton Res. 2011 Apr;21(2):69-72
pubmed: 21431947
J Pediatr. 2010 Jun;156(6):1019-1022.e1
pubmed: 20350727
J Pediatr. 2002 Apr;140(4):418-24
pubmed: 12006955
Cardiol Clin. 2013 Feb;31(1):89-100
pubmed: 23217690
Neuropathol Appl Neurobiol. 2013 Feb;39(2):90-108
pubmed: 23046254
QJM. 2009 May;102(5):335-9
pubmed: 19273552
J Clin Hypertens (Greenwich). 2002 Mar-Apr;4(2):139-45
pubmed: 11927799
Neurology. 2015 Oct 20;85(16):1362-7
pubmed: 26400576
Clin Auton Res. 2020 Feb;30(1):29-41
pubmed: 31222483
J Neurol. 2011 Feb;258(2):231-7
pubmed: 20820798
Clin Interv Aging. 2017 Jan 25;12:207-212
pubmed: 28182163
Clin Auton Res. 2008 Mar;18 Suppl 1:8-13
pubmed: 18368301
Ann Neurol. 2018 Mar;83(3):522-531
pubmed: 29405350
J Am Coll Cardiol. 2018 Sep 11;72(11):1294-1309
pubmed: 30190008
J Am Geriatr Soc. 2008 Oct;56(10):1816-20
pubmed: 18795982
Lancet. 2005 Apr 2-8;365(9466):1259-70
pubmed: 15811460
Auton Neurosci. 2012 Dec 24;172(1-2):1-3
pubmed: 23167992
Clin Auton Res. 2014 Aug;24(4):189-92
pubmed: 24710680
J Nucl Med. 2005 Nov;46(11):1775-81
pubmed: 16269589
Parkinsonism Relat Disord. 2014 Jan;20 Suppl 1:S62-7
pubmed: 24262191
Int J Cardiol. 2018 Nov 15;271:269-273
pubmed: 30223355
Neurology. 2010 Nov 23;75(21):1904-11
pubmed: 21098405
Circulation. 2006 Aug 15;114(7):630-6
pubmed: 16894039
Neurology. 2010 Feb 16;74(7):536-7
pubmed: 20157156
Br J Clin Pharmacol. 2012 Mar;73(3):348-62
pubmed: 21988193
J Gerontol A Biol Sci Med Sci. 2020 Jan 1;75(1):117-122
pubmed: 30169579
Eur Heart J. 2015 Jul 1;36(25):1609-17
pubmed: 25852216
BMJ. 2014 Sep 04;349:g5226
pubmed: 25189324