Serological tests using Sporothrix species antigens for the accurate diagnosis of sporotrichosis: a meta-analysis.
Antigens
Meta-analysis
Review
Serological test
Sporotrichosis
Journal
Diagnostic microbiology and infectious disease
ISSN: 1879-0070
Titre abrégé: Diagn Microbiol Infect Dis
Pays: United States
ID NLM: 8305899
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
22
05
2020
revised:
02
07
2020
accepted:
05
07
2020
pubmed:
18
8
2020
medline:
3
6
2021
entrez:
18
8
2020
Statut:
ppublish
Résumé
Some species of the fungus Sporothrix cause a chronic granulomatous infection in humans and animals called sporotrichosis. In the last decades, some research into serological tests has been carried out by different groups for the rapid detection of this infection. We performed a systematic review of the literature with meta-analysis to evaluate studies using Sporothrix spp. antigens and to evaluate their accuracy for sporotrichosis diagnostic. We searched Scopus, MEDLINE, Web of Science, GALE, Technology Research Database, DOA, Elsevier, SciELO, and Google Scholar Databases. The united results of sensitivity, specificity, positive and negative likelihood ratios, and diagnostic odds ratio with their corresponding 95% confidence intervals (CI) were assessed. A total of 15 assays from 8 studies using 7 different serological methods and 8 different antigens were analyzed. The studies were performed in the USA, Brazil, and Venezuela from 1973 until 2015 and presented good quality. A high heterogeneity for sensitivity [I
Identifiants
pubmed: 32805583
pii: S0732-8893(20)30508-3
doi: 10.1016/j.diagmicrobio.2020.115131
pii:
doi:
Substances chimiques
Antigens, Fungal
0
Immunodominant Epitopes
0
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
115131Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.