Wnt/β-Catenin and Hippo Pathway Deregulation in Mammary Tumors of Humans, Dogs, and Cats.

Animals Breast Neoplasms / veterinary Cat Diseases Cats Cell Transformation, Neoplastic Dog Diseases Dogs Female Hippo Signaling Pathway Humans Mammary Neoplasms, Animal Protein Serine-Threonine Kinases / metabolism Signal Transduction beta Catenin
ANKRD1 CCND1 CTGF Hippo pathway Wnt/β-catenin pathway YAP/TAZ breast cancer cats dogs mammary cancer

Journal

Veterinary pathology
ISSN: 1544-2217
Titre abrégé: Vet Pathol
Pays: United States
ID NLM: 0312020

Informations de publication

Date de publication:
11 2020
Historique:
pubmed: 19 8 2020
medline: 31 8 2021
entrez: 19 8 2020
Statut: ppublish

Résumé

Mammary cancer is a common neoplasm in women, dogs, and cats that still represents a therapeutic challenge. Wnt/β-catenin and Hippo pathways are involved in tumor progression, cell differentiation, and metastasis. The aim of this study was to evaluate mRNA and protein expression of molecules involved in these pathways in human (HBC), canine (CMT), and feline mammary tumors (FMT). Real-time quantitative polymerase chain reaction (qPCR) for

Identifiants

DOI: 10.1177/0300985820948823 PMID: 32807036
pubmed: 32807036
doi: 10.1177/0300985820948823
doi:

Substances chimiques

beta Catenin 0
Protein Serine-Threonine Kinases EC 2.7.11.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

774-790

Auteurs

Alessandro Sammarco (A)

Department of Comparative Biomedicine and Food Science, 9308University of Padua, Italy.
ORCID: 0000-0003-1977-3292

Chiara Gomiero (C)

Department of Comparative Biomedicine and Food Science, 9308University of Padua, Italy.
Department of Biomedical Sciences, 9308University of Padua, Italy.
Neuroscience Institute - Italian National Research Council (CNR), Padua, Italy.

Roberta Sacchetto (R)

Department of Comparative Biomedicine and Food Science, 9308University of Padua, Italy.

Giorgia Beffagna (G)

Department of Comparative Biomedicine and Food Science, 9308University of Padua, Italy.
Department of Cardio-Thoraco-Vascular Sciences and Public Health, 9308University of Padua, Italy.

Silvia Michieletto (S)

Breast Surgery Unit, Istituto Oncologico Veneto, IRCCS, Padua, Italy.

Enrico Orvieto (E)

Department of Pathology, Azienda Ospedaliera di Padova, Padua, Italy.
Department of Pathology, 18674Santa Maria della Misericordia Hospital, Rovigo, Italy.

Laura Cavicchioli (L)

Department of Comparative Biomedicine and Food Science, 9308University of Padua, Italy.

Maria Elena Gelain (ME)

Department of Comparative Biomedicine and Food Science, 9308University of Padua, Italy.

Silvia Ferro (S)

Department of Comparative Biomedicine and Food Science, 9308University of Padua, Italy.

Marco Patruno (M)

Department of Comparative Biomedicine and Food Science, 9308University of Padua, Italy.

Valentina Zappulli (V)

Department of Comparative Biomedicine and Food Science, 9308University of Padua, Italy.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Maladies de l'animal › Maladies des chats › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Carnivora › Feliformia › Felidae › Felis › Chats › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Carcinogenèse › Transformation cellulaire néoplasique › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Maladies de l'animal › Maladies des chiens › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Carnivora › Pinnipedia › Canidae › Chiens › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Voie de signalisation Hippo › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Maladies de l'animal › Tumeurs mammaires de l'animal › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Wnt/β-Catenin and Hippo Pathway Deregulation...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › bêta-Caténine › Wnt/β-Catenin and Hippo Pathway Deregulation...