Follicular dendritic cell sarcoma of the uterine cervix: a case report.
Antineoplastic Agents
/ administration & dosage
Carboplatin
/ administration & dosage
Combined Modality Therapy
Dendritic Cell Sarcoma, Follicular
/ drug therapy
Female
Humans
Hysterectomy
Lymph Node Excision
Middle Aged
Neoadjuvant Therapy
Neoplasm Recurrence, Local
Paclitaxel
/ administration & dosage
Salpingo-oophorectomy
Uterine Cervical Neoplasms
/ pathology
Cervical cancer
Follicular dendritic cell sarcoma
Journal
BMC women's health
ISSN: 1472-6874
Titre abrégé: BMC Womens Health
Pays: England
ID NLM: 101088690
Informations de publication
Date de publication:
17 08 2020
17 08 2020
Historique:
received:
26
04
2020
accepted:
04
08
2020
entrez:
19
8
2020
pubmed:
19
8
2020
medline:
12
2
2021
Statut:
epublish
Résumé
Follicular dendritic cell sarcoma (FDCS) is a rare mesenchymal tumor that mostly occurs in systemic lymph nodes. FDCS in the uterine cervix has not yet been reported. A 49-year-old woman was referred to our department with a cervical tumor, which was histologically suspected to be undifferentiated carcinoma. She underwent hysterectomy, salpingo-oophorectomy, and pelvic lymphadenectomy after neoadjuvant chemotherapy with paclitaxel and carboplatin. The resected specimen contained high numbers of spindle cells and was immunohistochemically confirmed to be FDCS. The tumor was completely resected and recurrence was not detected at a 16-month follow-up. FDCS is an extremely rare malignant tumor in the uterine cervix, and an accurate diagnosis and complete resection are essential for a good prognosis.
Sections du résumé
BACKGROUND
Follicular dendritic cell sarcoma (FDCS) is a rare mesenchymal tumor that mostly occurs in systemic lymph nodes. FDCS in the uterine cervix has not yet been reported.
CASE PRESENTATION
A 49-year-old woman was referred to our department with a cervical tumor, which was histologically suspected to be undifferentiated carcinoma. She underwent hysterectomy, salpingo-oophorectomy, and pelvic lymphadenectomy after neoadjuvant chemotherapy with paclitaxel and carboplatin. The resected specimen contained high numbers of spindle cells and was immunohistochemically confirmed to be FDCS. The tumor was completely resected and recurrence was not detected at a 16-month follow-up.
CONCLUSION
FDCS is an extremely rare malignant tumor in the uterine cervix, and an accurate diagnosis and complete resection are essential for a good prognosis.
Identifiants
pubmed: 32807169
doi: 10.1186/s12905-020-01045-y
pii: 10.1186/s12905-020-01045-y
pmc: PMC7433043
doi:
Substances chimiques
Antineoplastic Agents
0
Carboplatin
BG3F62OND5
Paclitaxel
P88XT4IS4D
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
182Références
Updates Surg. 2017 Sep;69(3):383-388
pubmed: 28466456
Cancer. 1997 Jan 15;79(2):294-313
pubmed: 9010103
Histopathology. 2002 Jul;41(1):1-29
pubmed: 12121233
Crit Rev Oncol Hematol. 2013 Nov;88(2):253-71
pubmed: 23755890
Hum Pathol. 1995 Oct;26(10):1093-8
pubmed: 7557942
Histopathology. 1991 Dec;19(6):523-8
pubmed: 1723957
J Histochem Cytochem. 2002 Nov;50(11):1475-86
pubmed: 12417613
Am J Pathol. 1986 Mar;122(3):562-72
pubmed: 2420185
Virchows Arch. 2006 Aug;449(2):148-58
pubmed: 16758173
Immunol Rev. 1990 Oct;117:185-211
pubmed: 2258191
J Minim Invasive Gynecol. 2020 Apr 19;:
pubmed: 32320800