Numerical simulation of the aqueous humor flow in the eye drainage system; a healthy and pathological condition comparison.
Anterior chamber
collector channels
glaucoma
intraocular pressure
segmental flow
Journal
Medical engineering & physics
ISSN: 1873-4030
Titre abrégé: Med Eng Phys
Pays: England
ID NLM: 9422753
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
07
11
2019
revised:
30
05
2020
accepted:
13
07
2020
entrez:
19
8
2020
pubmed:
19
8
2020
medline:
19
8
2021
Statut:
ppublish
Résumé
The present work describes the motion of aqueous humor through the anterior chamber and the trabecular drainage system, considering several distributions of the collector channels. The 3D computational model, implemented into the open-source software, was reconstructed from an optical coherence tomography. The model has been employed to simulate the aqueous humor dynamics considering buoyancy effects. The presence of the anterior chamber, the trabecular meshwork, and the Schlemm's canal were taken into consideration with 14 different distributions of collector channels. The influence of collector channels position on the intraocular pressure and shear stress has been analyzed, for a healthy and a glaucomatous condition. Aqueous humor velocity, pressure, temperature, wall shear stress, skin friction coefficient and Nusselt number, are presented for the different cases. The results indicate that the position of the collector channels has a strong influence on the wall shear stress on the Schlemm's canal and collector channels.
Identifiants
pubmed: 32807352
pii: S1350-4533(20)30108-9
doi: 10.1016/j.medengphy.2020.07.010
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
82-92Informations de copyright
Copyright © 2020 IPEM. Published by Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest None.