Electric field stimulates production of highly conductive microbial OmcZ nanowires.


Journal

Nature chemical biology
ISSN: 1552-4469
Titre abrégé: Nat Chem Biol
Pays: United States
ID NLM: 101231976

Informations de publication

Date de publication:
10 2020
Historique:
received: 13 02 2020
accepted: 09 07 2020
pubmed: 19 8 2020
medline: 15 12 2020
entrez: 19 8 2020
Statut: ppublish

Résumé

Multifunctional living materials are attractive due to their powerful ability to self-repair and replicate. However, most natural materials lack electronic functionality. Here we show that an electric field, applied to electricity-producing Geobacter sulfurreducens biofilms, stimulates production of cytochrome OmcZ nanowires with 1,000-fold higher conductivity (30 S cm

Identifiants

pubmed: 32807967
doi: 10.1038/s41589-020-0623-9
pii: 10.1038/s41589-020-0623-9
pmc: PMC7502555
mid: NIHMS1610866
doi:

Substances chimiques

Bacterial Proteins 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1136-1142

Subventions

Organisme : NIGMS NIH HHS
ID : T32 GM007223
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008283
Pays : United States
Organisme : NIAID NIH HHS
ID : DP2 AI138259
Pays : United States
Organisme : NIBIB NIH HHS
ID : T32 EB019941
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM116961
Pays : United States

Commentaires et corrections

Type : CommentIn

Références

Someya, T., Bao, Z. & Malliaras, G. G. The rise of plastic bioelectronics. Nature 540, 379–385 (2016).
pubmed: 27974769 doi: 10.1038/nature21004
Bathe, M. et al. Roadmap on biological pathways for electronic nanofabrication and materials. Nano Futures 3, 012001 (2019).
doi: 10.1088/2399-1984/aaf7d5
Zhang, B., Song, W., Brown, J., Nemanich, R. J. & Lindsay, S. Electronic conductance resonance in non-redox proteins. J. Am. Chem. Soc. 142, 6432–6438 (2020).
pubmed: 32176496 doi: 10.1021/jacs.0c01805 pmcid: 7185870
Wang, F. et al. Structure of microbial nanowires reveals stacked hemes that transport electrons over micrometers. Cell 177, 361–369 (2019).
pubmed: 30951668 pmcid: 6720112 doi: 10.1016/j.cell.2019.03.029
Reguera, G. et al. Extracellular electron transfer via microbial nanowires. Nature 435, 1098–1101 (2005).
pubmed: 15973408 doi: 10.1038/nature03661
Mehta, T., Coppi, M. V., Childers, S. E. & Lovley, D. R. Outer membrane c-type cytochromes required for Fe(III) and Mn(IV) oxide reduction in Geobacter sulfurreducens. Appl. Environ. Microbiol. 71, 8634–8641 (2005).
pubmed: 16332857 pmcid: 1317342 doi: 10.1128/AEM.71.12.8634-8641.2005
Malvankar, N. S. et al. Tunable metallic-like conductivity in microbial nanowire networks. Nat. Nanotechnol. 6, 573–579 (2011).
pubmed: 21822253 doi: 10.1038/nnano.2011.119
Inoue, K. et al. Purification and characterization of omcZ, an outer-surface, octaheme c-type cytochrome essential for optimal current production by Geobacter sulfurreducens. Appl. Environ. Microbiol. 76, 3999–4007 (2010).
pubmed: 20400562 pmcid: 2893489 doi: 10.1128/AEM.00027-10
Nevin, K. P. et al. Anode biofilm transcriptomics reveals outer surface components essential for high density current production in Geobacter sulfurreducens fuel cells. PLoS ONE 4, e5628 (2009).
pubmed: 19461962 pmcid: 2680965 doi: 10.1371/journal.pone.0005628
Inoue, K. et al. Specific localization of the c-type cytochrome OmcZ at the anode surface in current-producing biofilms of Geobacter sulfurreducens. Environ. Microbiol. Rep. 3, 211–217 (2010).
pubmed: 23761253 doi: 10.1111/j.1758-2229.2010.00210.x
Malvankar, N. S., Tuominen, M. T. & Lovley, D. R. Lack of cytochrome involvement in long-range electron transport through conductive biofilms and nanowires of Geobacter sulfurreducens. Energy Environ. Sci. 5, 8651–8659 (2012).
doi: 10.1039/c2ee22330a
Amenabar, I. et al. Structural analysis and mapping of individual protein complexes by infrared nanospectroscopy. Nat. Commun. 4, 2890 (2013).
pubmed: 24301518 doi: 10.1038/ncomms3890
O’Brien, J. P. & Malvankar, N. S. A simple and low-cost procedure for growing Geobacter sulfurreducens cell cultures and biofilms in bioelectrochemical systems. Curr. Protoc. Microbiol. 43, A.4K.1–A.4K.27 (2017).
Tan, Y. et al. Synthetic biological protein nanowires with high conductivity. Small 12, 4481–4485 (2016).
pubmed: 27409066 doi: 10.1002/smll.201601112
Richter, L. V., Sandler, S. J. & Weis, R. M. Two isoforms of Geobacter sulfurreducens PilA have distinct roles in pilus biogenesis, cytochrome localization, extracellular electron transfer, and biofilm formation. J. Bacteriol. 194, 2551–2563 (2012).
pubmed: 22408162 pmcid: 3347174 doi: 10.1128/JB.06366-11
Liu, X., Zhuo, S., Rensing, C. & Zhou, S. Syntrophic growth with direct interspecies electron transfer between pili-free Geobacter species. ISME J. 12, 2142–2151 (2018).
pubmed: 29875437 pmcid: 6092431 doi: 10.1038/s41396-018-0193-y
Barth, A. Infrared spectroscopy of proteins. Biochim. Biophys. Acta 1767, 1073–1101 (2007).
pubmed: 17692815 doi: 10.1016/j.bbabio.2007.06.004
Yalcin, S. E., Legg, B. A., Yeşilbaş, M., Malvankar, N. S. & Boily, J. Direct observation of anisotropic growth of water films on minerals driven by defects and surface tension. Sci. Adv. 6, eaaz9708 (2020).
pubmed: 32832658 pmcid: 7439304 doi: 10.1126/sciadv.aaz9708
Berweger, S. et al. Nano-chemical infrared imaging of membrane proteins in lipid bilayers. J. Am. Chem. Soc. 135, 18292–18295 (2013).
pubmed: 24251914 doi: 10.1021/ja409815g
Yang, H., Yang, S., Kong, J., Dong, A. & Yu, S. Obtaining information about protein secondary structures in aqueous solution using Fourier transform IR spectroscopy. Nat. Protoc. 10, 382–396 (2015).
pubmed: 25654756 doi: 10.1038/nprot.2015.024
Qian, X. et al. Biochemical characterization of purified OmcS, a c-type cytochrome required for insoluble Fe(III) reduction in Geobacter sulfurreducens. Biochim. Biophys. Acta 1807, 404–412 (2011).
pubmed: 21236241 doi: 10.1016/j.bbabio.2011.01.003
Chadwick, G. L., Otero, F. J., Gralnick, J. A., Bond, D. R. & Orphan, V. J. NanoSIMS imaging reveals metabolic stratification within current-producing biofilms. Proc. Natl Acad. Sci. USA 116, 20716–20724 (2019).
pubmed: 31548422 doi: 10.1073/pnas.1912498116 pmcid: 6789570
Ho Choi, S., Kim, B. & Frisbie, C. D. Electrical resistance of long conjugated molecular wires. Science 320, 1482–1486 (2008).
pubmed: 18556556 doi: 10.1126/science.1156538
Lee, K. et al. Metallic transport in polyaniline. Nature 441, 65–68 (2006).
pubmed: 16672965 doi: 10.1038/nature04705
Valasatava, Y., Andreini, C. & Rosato, A. Hidden relationships between metalloproteins unveiled by structural comparison of their metal sites. Sci. Rep. 5, 9486 (2015).
pubmed: 25820752 pmcid: 4377587 doi: 10.1038/srep09486
Janiak, C. A critical account on π-π stacking in metal complexes with aromatic nitrogen-containing ligands. J. Chem. Soc., Dalton Trans. 2000, 3885–3896 (2000).
Adhikari, R., Malvankar, N., Tuominen, M. & Lovley, D. Conductivity of individual Geobacter pili. RSC Adv. 6, 8354–8357 (2016).
doi: 10.1039/C5RA28092C
Malvankar, N. S. et al. Structural basis for metallic-like conductivity in microbial nanowires. mBio 6, e00084–00015 (2015).
pubmed: 25736881 pmcid: 4453548 doi: 10.1128/mBio.00084-15
Donhauser, Z. J. et al. Conductance switching in single molecules through conformational changes. Science 292, 2303–2307 (2001).
pubmed: 11423655 doi: 10.1126/science.1060294
Su, T. A., Li, H., Steigerwald, M. L., Venkataraman, L. & Nuckolls, C. Stereoelectronic switching in single-molecule junctions. Nat. Chem. 7, 215–220 (2015).
pubmed: 25698330 doi: 10.1038/nchem.2180
Li, C., Wang, Z., Lu, Y., Liu, X. & Wang, L. Conformation-based signal transfer and processing at the single-molecule level. Nat. Nanotechnol. 12, 1071 (2017).
pubmed: 28920965 doi: 10.1038/nnano.2017.179
Simone, R. F. et al. Influence of the β‐sheet content on the mechanical properties of aggregates during amyloid fibrillization. Angew. Chem. Int. Ed. 54, 2462–2466 (2015).
doi: 10.1002/anie.201409050
Freund, J., Halbritter, J. & Hörber, J. How dry are dried samples? Water adsorption measured by STM. Microsc. Res. Tech. 44, 327–338 (1999).
pubmed: 10090207 doi: 10.1002/(SICI)1097-0029(19990301)44:5<327::AID-JEMT3>3.0.CO;2-E
Rygula, A. et al. Raman spectroscopy of proteins: a review. J. Raman Spectrosc. 44, 1061–1076 (2013).
doi: 10.1002/jrs.4335
Sreerama, N. & Woody, R. W. Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. Anal. Biochem. 287, 252–260 (2000).
pubmed: 11112271 doi: 10.1006/abio.2000.4880
Greenfield, N. J. Using circular dichroism spectra to estimate protein secondary structure. Nat. Protoc. 1, 2876–2890 (2006).
pubmed: 17406547 pmcid: 2728378 doi: 10.1038/nprot.2006.202
Guterman, T. et al. Formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides. Nat. Commun. 7, 13482 (2016).
pubmed: 27853136 pmcid: 5473601 doi: 10.1038/ncomms13482
Boyken, S. E. et al. De novo design of tunable, pH-driven conformational changes. Science 364, 658–664 (2019).
pubmed: 31097662 pmcid: 7072037 doi: 10.1126/science.aav7897
Koga, T., Taguchi, K., Kobuke, Y., Kinoshita, T. & Higuchi, M. Structural regulation of a peptide‐conjugated graft copolymer: a simple model for amyloid formation. Chem.–A Eur. J. 9, 1146–1156 (2003).
doi: 10.1002/chem.200390132
Cerpa, R., Cohen, F. E. & Kuntz, I. D. Conformational switching in designed peptides: the helix/sheet transition. Fold. Des. 1, 91–101 (1996).
pubmed: 9079369 doi: 10.1016/S1359-0278(96)00018-1
Cote, Y. et al. Mechanism of the pH-controlled self-assembly of nanofibers from peptide amphiphiles. J. Phys. Chem. C. 118, 16272–16278 (2014).
doi: 10.1021/jp5048024
Haldar, S., Sil, P., Thangamuniyandi, M. & Chattopadhyay, K. Conversion of amyloid fibrils of cytochrome c to mature nanorods through a honeycomb morphology. Langmuir 31, 4213–4223 (2015).
pubmed: 25338286 doi: 10.1021/la5029993
Wang, X., Ye, X. & Zhang, G. Investigation of pH-induced conformational change and hydration of poly (methacrylic acid) by analytical ultracentrifugation. Soft Matter 11, 5381–5388 (2015).
pubmed: 26059391 doi: 10.1039/C5SM00806A
Esquerra, R. M. et al. The pH dependence of heme pocket hydration and ligand rebinding kinetics in photodissociated carbonmonoxymyoglobin. J. Biol. Chem. 283, 14165–14175 (2008).
pubmed: 18359768 pmcid: 2376230 doi: 10.1074/jbc.M709710200
Durchschlag, H. & Zipper, P. Modeling the hydration of proteins at different pH values. Anal. Ultracentrif. VII 127, 98–112 (2004).
doi: 10.1007/b98019
Tschirhart, T. et al. Electronic control of gene expression and cell behaviour in Escherichia coli through redox signalling. Nat. Commun. 8, 14030 (2017).
pubmed: 28094788 pmcid: 5247576 doi: 10.1038/ncomms14030
Park, I. & Kim, B.-C. Homologous overexpression of omcZ, a gene for an outer surface c-type cytochrome of Geobacter sulfurreducens by single-step gene replacement. Biotechnol. Lett. 33, 2043 (2011).
pubmed: 21698445 doi: 10.1007/s10529-011-0668-7
Vargas, M. et al. Aromatic amino acids required for pili conductivity and long-range extracellular electron transport in Geobacter sulfurreducens. mBio 4, e00105–e00113 (2013).
pubmed: 23481602 pmcid: 3604773 doi: 10.1128/mBio.00105-13
Wang, F. et al. Cryoelectron microscopy reconstructions of the Pseudomonas aeruginosa and Neisseria gonorrhoeae type IV pili at sub-nanometer resolution. Structure 25, 1423–1435 (2017).
pubmed: 28877506 doi: 10.1016/j.str.2017.07.016 pmcid: 8189185
Silva, J. C., Gorenstein, M. V., Li, G.-Z., Vissers, J. P. & Geromanos, S. J. Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition. Mol. Cell. Proteom. 5, 144–156 (2006).
doi: 10.1074/mcp.M500230-MCP200
Grossmann, J. et al. Implementation and evaluation of relative and absolute quantification in shotgun proteomics with label-free methods. J. Proteom. 73, 1740–1746 (2010).
doi: 10.1016/j.jprot.2010.05.011
Krey, J. F. et al. Accurate label-free protein quantitation with high-and low-resolution mass spectrometers. J. Proteome Res. 13, 1034–1044 (2013).
pubmed: 24295401 pmcid: 3946283 doi: 10.1021/pr401017h
Erickson, H. P. Size and shape of protein molecules at the nanometer level determined by sedimentation, gel filtration, and electron microscopy. Biol. Proced. 11, 32 (2009).
doi: 10.1007/s12575-009-9008-x
Qin, N. et al. Nanoscale probing of electron-regulated structural transitions in silk proteins by near-field IR imaging and nano-spectroscopy. Nat. Commun. 7, 1–8 (2016).
Paulite, M. et al. Imaging secondary structure of individual amyloid fibrils of a β2-microglobulin fragment using near-field infrared spectroscopy. J. Am. Chem. Soc. 133, 7376–7383 (2011).
pubmed: 21524071 doi: 10.1021/ja109316p
Ramer, G., Ruggeri, F. S., Levin, A., Knowles, T. P. & Centrone, A. Determination of polypeptide conformation with nanoscale resolution in water. ACS Nano 12, 6612–6619 (2018).
pubmed: 29932670 doi: 10.1021/acsnano.8b01425
Ruggeri, F. et al. Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation. Nat. Commun. 6, 1–9 (2015).
doi: 10.1038/ncomms8831
Ruggeri, F. et al. Nanoscale studies link amyloid maturity with polyglutamine diseases onset. Sci. Rep. 6, 1–11 (2016).
doi: 10.1038/srep31155
Kocun, M., Labuda, A., Meinhold, W., Revenko, I. & Proksch, R. Fast, high resolution, and wide modulus range nanomechanical mapping with bimodal tapping mode. ACS Nano 11, 10097–10105 (2017).
pubmed: 28953363 doi: 10.1021/acsnano.7b04530
Bruckner, S. Estimation of the background in powder diffraction patterns through a robust smoothing procedure. J. Appl. Crystallogr. 33, 977–979 (2000).
doi: 10.1107/S0021889800003617

Auteurs

Sibel Ebru Yalcin (SE)

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA. sibel.yalcin@yale.edu.
Microbial Sciences Institute, Yale University, New Haven, CT, USA. sibel.yalcin@yale.edu.

J Patrick O'Brien (JP)

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Microbial Sciences Institute, Yale University, New Haven, CT, USA.

Yangqi Gu (Y)

Microbial Sciences Institute, Yale University, New Haven, CT, USA.
Department of Molecular, Cellular & Developmental Biology, Yale University, New Haven, CT, USA.

Krystle Reiss (K)

Department of Chemistry, Yale University, New Haven, CT, USA.

Sophia M Yi (SM)

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Microbial Sciences Institute, Yale University, New Haven, CT, USA.

Ruchi Jain (R)

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Microbial Sciences Institute, Yale University, New Haven, CT, USA.

Vishok Srikanth (V)

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Microbial Sciences Institute, Yale University, New Haven, CT, USA.

Peter J Dahl (PJ)

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Microbial Sciences Institute, Yale University, New Haven, CT, USA.

Winston Huynh (W)

Microbial Sciences Institute, Yale University, New Haven, CT, USA.
Department of Biomedical Engineering, Yale University, New Haven, CT, USA.

Dennis Vu (D)

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Microbial Sciences Institute, Yale University, New Haven, CT, USA.

Atanu Acharya (A)

Department of Chemistry, Yale University, New Haven, CT, USA.

Subhajyoti Chaudhuri (S)

Department of Chemistry, Yale University, New Haven, CT, USA.

Tamas Varga (T)

Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA.

Victor S Batista (VS)

Department of Chemistry, Yale University, New Haven, CT, USA.

Nikhil S Malvankar (NS)

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA. nikhil.malvankar@yale.edu.
Microbial Sciences Institute, Yale University, New Haven, CT, USA. nikhil.malvankar@yale.edu.

Articles similaires

Photosynthesis Ribulose-Bisphosphate Carboxylase Carbon Dioxide Molecular Dynamics Simulation Cyanobacteria
Humans Trigeminal Neuralgia Trigeminal Nerve Rhizotomy Electric Stimulation

Two codependent routes lead to high-level MRSA.

Abimbola Feyisara Adedeji-Olulana, Katarzyna Wacnik, Lucia Lafage et al.
1.00
Methicillin-Resistant Staphylococcus aureus Penicillin-Binding Proteins Peptidoglycan Bacterial Proteins Anti-Bacterial Agents
Humans Spinal Cord Male Electrophysiological Phenomena Adult

Classifications MeSH