Molecular mechanism of antimutagenicity by an ethoxy-substituted phylloquinone (vitamin K1 derivative) from spinach (Spinacea oleracea L.).
Cell division
DNA minor groove
DNA repair
E. coli knockouts
Ethoxy-substituted phylloquinone
Proteomics
Journal
Chemico-biological interactions
ISSN: 1872-7786
Titre abrégé: Chem Biol Interact
Pays: Ireland
ID NLM: 0227276
Informations de publication
Date de publication:
01 Oct 2020
01 Oct 2020
Historique:
received:
13
11
2019
revised:
24
07
2020
accepted:
31
07
2020
pubmed:
19
8
2020
medline:
21
10
2020
entrez:
19
8
2020
Statut:
ppublish
Résumé
In our previous study, an antimutagenic compound from spinach (Spinacea oleracea L.), ethoxy-substituted phylloquinone (ESP) was isolated and characterized. The current study deals with elucidation of the possible mechanism of antimutagenicity of ESP against ethyl methanesulfonate (EMS) deploying model systems such as human lymphoblast (TK
Identifiants
pubmed: 32810488
pii: S0009-2797(19)31971-4
doi: 10.1016/j.cbi.2020.109216
pii:
doi:
Substances chimiques
Vitamin K 1
84-80-0
DNA
9007-49-2
calf thymus DNA
91080-16-9
Lyases
EC 4.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
109216Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.