Population-based risk assessment of second primary cancers following a first head and neck cancer: patterns of association and difficulties of its analysis.
Cohort Studies
Female
Head and Neck Neoplasms
/ classification
Humans
Incidence
Male
Middle Aged
Neoplasm Recurrence, Local
Neoplasms, Second Primary
/ epidemiology
Registries
/ statistics & numerical data
Retrospective Studies
Risk Assessment
Sex Distribution
Sex Factors
Spain
/ epidemiology
Time Factors
Cancer registries
Epidemiology
Head and neck cancer
Neoplasms
second primary
Journal
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
ISSN: 1699-3055
Titre abrégé: Clin Transl Oncol
Pays: Italy
ID NLM: 101247119
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
02
06
2020
accepted:
01
08
2020
pubmed:
21
8
2020
medline:
18
9
2021
entrez:
21
8
2020
Statut:
ppublish
Résumé
The diagnosis of a second primary cancer (SPC) is a major concern in the follow-up of survivors of a primary head and neck cancer (HNC), but the anatomic subsites in the head and neck area are close, making it difficult to distinguish a SPC of a recurrence and therefore register it correctly. We performed a retrospective cohort study using data from two population-based cancer registries in Catalonia, Spain: the Tarragona Cancer Registry and the Girona Cancer Registry. All patients diagnosed with HNC during the period 1994-2013 were registered and followed-up to collect cases of SPC. We analysed the standardized incidence ratio (SIR) and the excess absolute risk (EAR) to determine the risk of second malignancies following a prior HNC. 923 SPC were found in a cohort of 5646 patients diagnosed of a first head and neck cancer. Men had an increased risk of a SPC with a SIR of 2.22 and an EAR of 216.76. Women also had an increased risk with a SIR of 2.02 and an EAR of 95.70. We show the risk for different tumour sites and discuss the difficulties of the analysis. The risks of a SPC following a prior HNC in Tarragona and Girona are similar to those previously found in other similar cohorts. It would appear to be advisable to make a revision of the international rules of classification of multiple tumours, grouping the sites of head and neck area with new aetiological criteria to better determine and interpret the risks of SPC obtained in these studies.
Identifiants
pubmed: 32815088
doi: 10.1007/s12094-020-02470-z
pii: 10.1007/s12094-020-02470-z
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
788-798Références
Schou G, Storm HH, Jensen OM. Second cancer following cancers of the buccal cavity and pharynx in Denmark, 1943–80. Natl Cancer Inst Monogr. 1985;68:253–76.
pubmed: 4088302
Wood ME, Vogel V, Ng A, Foxhall L, Goodwin P, Travis LB. Second malignant neoplasms: assessment and strategies for risk reduction. J Clin Oncol. 2012;30(30):3734–45.
doi: 10.1200/JCO.2012.41.8681
Slaughter M, Danely P, Harry W, et al. Field cancerization in oral stratified squamous epithelium clinical implications of multicentric origin. Cancer. 1953;6:963–8.
doi: 10.1002/1097-0142(195309)6:5<963::AID-CNCR2820060515>3.0.CO;2-Q
Mohan M, Jagannathan N. Oral field cancerization: an update on current concepts. Oncology Rev. 2014;8:244–50.
Ha PK, Califano JA. The molecular biology of mucosal field cancerization of the head and neck. Crit Rev Oral Biol Med. 2003;14:363–9.
doi: 10.1177/154411130301400506
Martel M, Alemany L, Taberna M, Mena M, Tous S, Bagué S, et al. The role of HPV on the risk of second primary neoplasia in patients with oropharyngeal carcinoma. Oral Oncol. 2017;64:37–433.
doi: 10.1016/j.oraloncology.2016.11.011
Engeland A, Bjorge T, Haldorsen T, Tretli S. Use of multiple primary cancers to indicate associations between smoking and cancer incidence: an analysis of 500000 cancer cases diagnosed in Norway during 1953–93. Int J Cancer. 1997;70:401–4017.
doi: 10.1002/(SICI)1097-0215(19970207)70:4<401::AID-IJC5>3.0.CO;2-#
Shiels MS, Gibson T, Sampson J, Albanes D, Andreotti G, Freeman LB, Berrington de Gonzalez A, Caporaso N, Curtis RE, Elena J, Freedman ND, Robien K, Black A, Morton LM. Cigarette smoking prior to first cancer and risk of second smoking-associated cancers among survivors of bladder, kidney, head and neck, and stage I lung cancers. J Clin Oncol. 2014;32(35):3989–95.
doi: 10.1200/JCO.2014.56.8220
Berg JW. Morphologic classification of human cancer. In: Schottenfeld D & Fraumeni JF. Jr. Cancer epidemiology and prevention, 1982, Chapter 5, pp 74–89. Saunders Company
(2005) Working Group of the International Association of Cancer Registries. International rules for multiple primary cancers (ICD-0 third edition). Eur J Cancer Prev. 14(4):307–308.
(1992) International statistical classification of diseases and related health problems, tenth revision. World Health Organization, Geneva.
Brown LM, McCarron P, Freedman M. Chapter 3: New malignancies following cancer of the buccal cavity and pharynx. In: Curtis RE, Freedman DM, Ron E, Ries LAG, Hacker DG, Edwards BK, Tucker MA, Fraumeni JF Jr. (eds). New malignancies among Cancer survivors: SEER Cancer Registries, 1973–2000. National Cancer Institute, NIH Publ. No. 05–5302. Bethesda, MD, 2006
Castellsagué X, Alemany L, Quer M, Halec G, Quirós B, Tous S, et al. HPV involvement in head and neck cancers: comprehensive assessment of biomarkers in 3680 patients. J Natl Cancer Inst. 2016;108(6):djv403.
doi: 10.1093/jnci/djv403
Gillison ML, Koch WM, Capone RB, Spafford M, Westra WH, Wu L, et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst. 2000;92(9):709–20.
doi: 10.1093/jnci/92.9.709
Lubin JH, Purdue M, Kelsey K, Zhang ZF, Winn D, Wei Q, et al. Total exposure and exposure rate effects for alcohol and smoking and risk of head and neck cancer: a pooled analysis of case-control studies. Am J Epidemiol. 2009;170(8):937–47.
doi: 10.1093/aje/kwp222
Morris LG, Sikora AG, Hayes RB, Patel SG, Ganly I. Anatomic sites at elevated risk of second primary cancer after an index head and neck cancer. Cancer Causes Control. 2011;22(5):671–9.
doi: 10.1007/s10552-011-9739-2
Bosetti C, Scelo G, Chuang SC, Tonita JM, Tamaro S, Jonasson JG, Kliewer EV, Hemminki K, Weiderpass E, Pukkala E, Tracey E, Olsen JH, Pompe-Kirn V, Brewster DH, Martos C, Chia KS, Brennan P, Hashibe M, Levi F, La Vecchia C, Boffetta P. High constant incidence rates of second primary cancers of the head and neck: a pooled analysis of 13 cancer registries. Int J Cancer. 2011;129(1):173–9.
doi: 10.1002/ijc.25652
Coca-Palez A, Rodrigo JP, Suárez C, Nixon IJ, Mäkitie A, Sanabria A, et al. The risk of second primary tumours in head and neck cancer: a systematic review. Head Neck. 2020;42(3):456–66.
doi: 10.1002/hed.26016
Chaturvedi AK, Engels EA, Pfeiffer RM, et al. Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol. 2011;29:4294–301.
doi: 10.1200/JCO.2011.36.4596
Morris LG, Sikora AG, Patel SG, Hayes RB, Ganly I. Second primary cancers after an index head and neck cancer: subsite-specific trends in the era of human papillomavirus-associated oropharyngeal cancer. J Clin Oncol. 2010;29:739–46.
doi: 10.1200/JCO.2010.31.8311
Neumann F, Jégu J, Mougin C, Prétet JL, Guizard AV, Lapôtre-Ledoux B, Bara S, Bouvier V, Colonna M, Troussard X, Trétarre B, Grosclaude P, Velten M, Woronoff AS. Risk of second primary cancer after a first potentially-human papillomavirus-related cancer: a population-based study. Prev Med. 2016;90:52–8.
doi: 10.1016/j.ypmed.2016.06.041
Suk R, Mahale P, Sonawane K, Sikora AG, Chhatwal J, Schmeler KM, Sigel K, Cantor SB, Chiao EY, Deshmukh A. Trends in risks for second primary cancers associated with index human papillomavirus-associated cancers. JAMA Network Open. 2018;1(5):e181999.
doi: 10.1001/jamanetworkopen.2018.1999
Jégu J, Colonna M, Daubisse-Marliac L, Trétarre B, Ganry O, Guizard AV, Bara S, Troussard X, Bouvier V, Woronoff AS, Velten M. The effect of patient characteristics on second primary cancer risk in France. BMC Cancer. 2014;14:94–107.
doi: 10.1186/1471-2407-14-94
Curtis RE, Freedman DM, Ron E, Ries LAG, Hacker DG, Edwards BK, Tucker MA, Fraumeni JF. New malignancies among cancer survivors: SEER Cancer Registries, 1973–2000. National Cancer Institute, NIH Publ. No 05–5302. Bethesda, MD, 2006
Buzzoni C, Crocetti E. AIRTUM working group. italian cancer figures report 2013: multiple tumours. Epidemiol Prev. 2013;37((4–5) suppl 1):1–152.
Weir HK, Johnson CJ, Ward KC, Coleman MP. The effect of multiple primary rules on cancer incidence rates and trends. Cancer Causes Control. 2016;3:377–90.
doi: 10.1007/s10552-016-0714-9
Ye Y, Neil AL, Wills KE, Venn AJ. Temporal trends in the risk of developing multiple primary cancers: a systematic review. BMC Cancer. 2016;16(1):849–66.
doi: 10.1186/s12885-016-2876-y