Lichen sclerosus and hidradenitis suppurativa: Two case reports of a new possible association.
autoimmunity
comorbidity
hidradenitis suppurativa
lichen sclerosus
Journal
The Australasian journal of dermatology
ISSN: 1440-0960
Titre abrégé: Australas J Dermatol
Pays: Australia
ID NLM: 0135232
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
24
03
2020
revised:
22
06
2020
accepted:
03
07
2020
pubmed:
21
8
2020
medline:
28
10
2021
entrez:
21
8
2020
Statut:
ppublish
Résumé
We report the cases of two women affected by lichen sclerosus also having clinical signs of hidradenitis suppurativa. Lichen sclerosus is a chronic autoimmune disease, in which activated fibroblasts produce significantly altered collagen leading to fibrosis Hidradenitis suppurativa is a chronic relapsing inflammatory disease affecting folliculopilosebaceous unit and apocrine gland, which lesions are nodules and abscesses. The association between lichen sclerosus and autoimmune disorders is well known, but not the one with hidradenitis suppurativa. We present two case reports of these unusual comorbidities.
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e92-e94Informations de copyright
© 2020 The Australasian College of Dermatologists.
Références
Chamli A, Souissi A. Lichen Sclerosus. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.
Sabat R, Jemec GBE, Matusiak Ł, Kimball AB, Prens E, Wolk K. Hidradenitis suppurativa. Nat. Rev. Dis. Primers. 2020; 6: 18.
Constantinou CA, Fragoulis GE, Nikiphorou E. Hidradenitis suppurativa: infection, autoimmunity, or both? Ther. Adv. Musculoskelet. Dis. 2019; 11: 1759720X19895488.
Kreuter A, Kryvosheyeva Y, Terras S, et al. Association of autoimmune diseases with lichen sclerosus in 532 male and female patients. Acta Derm.-Venereol. 2013; 93: 238-41.
Marfatia Y, Surani A, Baxi R. Genital lichen sclerosus et atrophicus in females: An update. Indian J. Sex Transm. Dis. AIDS 2019; 40: 6-12.
Fergus KB, Lee AW, Baradaran N, et al. Pathophysiology, clinical manifestations, and treatment of lichen sclerosus: a systematic review. Urology 2020; 135: 11-9.
Seyed Jafari SM, Hunger RE, Schlapbach C. Hidradenitis suppurativa: current understanding of pathogenic mechanisms and suggestion for treatment algorithm. Front. Med. (Lausanne) 2020; 7: 68.