Autologous fat grafting for the treatment of sclerotic lesions and scars.
Adipose-derived stem cells
Atrophy
Fat grafting
Fat injection
Fibrosis
Scar
Sclerotic lesion
Journal
Annales de dermatologie et de venereologie
ISSN: 0151-9638
Titre abrégé: Ann Dermatol Venereol
Pays: France
ID NLM: 7702013
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
28
10
2019
revised:
06
05
2020
accepted:
17
06
2020
pubmed:
21
8
2020
medline:
16
10
2021
entrez:
22
8
2020
Statut:
ppublish
Résumé
Microfat grafting is a well-known technique that is underutilized in dermatology. Instead of removing sclerotic tissue, microfat grafting preserves the tissue and uses stem cells for remodeling its structure into normal tissue. We performed a retrospective study of patients treated with microfat grafting for sclerotic and atrophic skin lesions and scars. Seventy-two microfat grafts were performed using the Magalon technique under general anaesthesia for the treatment of sclerotic and atrophic skin lesions. We performed grafts for different indications, such as scars (n=55) and sclerotic and atrophic skin lesions (n=17: Parry-Romberg syndrome, morphea). The main outcome was assessed for satisfaction during follow-up. In addition, an independent committee judged the results based on photographs. Satisfaction levels (e.g. results were judged to be "good") were almost 91% (n=50/55) for scars and 100% (n=17/17) for atrophic and sclerotic skin lesions. Satisfaction levels according to the independent committee were 94.1% for sclerotic and atrophic lesions and nearly 51% for scars. Satisfaction was high after microfat grafting for atrophic and sclerotic skin lesions. Microfat grafting enabled restoration of the skin texture by exploiting stem cell properties. It is an efficient dermatological therapy for sclerotic and atrophic lesions, for which there are few alternative treatments.
Identifiants
pubmed: 32819743
pii: S0151-9638(20)30308-2
doi: 10.1016/j.annder.2020.06.022
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
40-44Informations de copyright
Copyright © 2020 Elsevier Masson SAS. All rights reserved.