Autologous fat grafting for the treatment of sclerotic lesions and scars.


Journal

Annales de dermatologie et de venereologie
ISSN: 0151-9638
Titre abrégé: Ann Dermatol Venereol
Pays: France
ID NLM: 7702013

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 28 10 2019
revised: 06 05 2020
accepted: 17 06 2020
pubmed: 21 8 2020
medline: 16 10 2021
entrez: 22 8 2020
Statut: ppublish

Résumé

Microfat grafting is a well-known technique that is underutilized in dermatology. Instead of removing sclerotic tissue, microfat grafting preserves the tissue and uses stem cells for remodeling its structure into normal tissue. We performed a retrospective study of patients treated with microfat grafting for sclerotic and atrophic skin lesions and scars. Seventy-two microfat grafts were performed using the Magalon technique under general anaesthesia for the treatment of sclerotic and atrophic skin lesions. We performed grafts for different indications, such as scars (n=55) and sclerotic and atrophic skin lesions (n=17: Parry-Romberg syndrome, morphea). The main outcome was assessed for satisfaction during follow-up. In addition, an independent committee judged the results based on photographs. Satisfaction levels (e.g. results were judged to be "good") were almost 91% (n=50/55) for scars and 100% (n=17/17) for atrophic and sclerotic skin lesions. Satisfaction levels according to the independent committee were 94.1% for sclerotic and atrophic lesions and nearly 51% for scars. Satisfaction was high after microfat grafting for atrophic and sclerotic skin lesions. Microfat grafting enabled restoration of the skin texture by exploiting stem cell properties. It is an efficient dermatological therapy for sclerotic and atrophic lesions, for which there are few alternative treatments.

Identifiants

pubmed: 32819743
pii: S0151-9638(20)30308-2
doi: 10.1016/j.annder.2020.06.022
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

40-44

Informations de copyright

Copyright © 2020 Elsevier Masson SAS. All rights reserved.

Auteurs

J-M L'Orphelin (JM)

Dermatology, Caen Hospital, avenue Côte-de-Nacre, Caen, France. Electronic address: jean.matthieu.lorphelin@gmail.com.

R Garmi (R)

Maxillofacial surgery, Caen Hospital, avenue Côte-de-Nacre, Caen, France.

D Labbé (D)

Plastic surgery, centre hospitalier privé Saint-Martin, Caen, France.

H Benateau (H)

Maxillofacial surgery, Caen Hospital, avenue Côte-de-Nacre, Caen, France.

A Dompmartin (A)

Dermatology, Caen Hospital, avenue Côte-de-Nacre, Caen, France.

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Classifications MeSH