New Insights into the Pathogenesis, Risk Factors, and Treatment of Portal Vein Thrombosis in Patients with Cirrhosis.

Female Humans Liver Cirrhosis / complications Male Risk Factors Venous Thrombosis / etiology

Journal

Seminars in thrombosis and hemostasis
ISSN: 1098-9064
Titre abrégé: Semin Thromb Hemost
Pays: United States
ID NLM: 0431155

Informations de publication

Date de publication:
Sep 2020
Historique:
pubmed: 21 8 2020
medline: 24 6 2021
entrez: 22 8 2020
Statut: ppublish

Résumé

Portal vein thrombosis (PVT) is a frequent event in patients with cirrhosis regardless of etiology. Notwithstanding the commonality of the problem, the pathophysiology and risk factors for PVT in cirrhosis are largely unknown. The clinical impact of PVT in the natural history of cirrhosis is unclear, indications for PVT treatment are not well defined, and treatment recommendations are based on experts' opinion and consensus only. Therefore, this review aims to summarize current knowledge of mechanisms and risk factors for PVT development and assess the current evidence of PVT management, with a special focus on strategies of anticoagulation and transjugular intrahepatic portosystemic shunt placement.

Identifiants

DOI: 10.1055/s-0040-1715473 PMID: 32820481
pubmed: 32820481
doi: 10.1055/s-0040-1715473
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

673-681

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

J.C.G.P. reports other fees from Cook Medical, Shionogi, W. L. Gore & Associates, Conatus Pharmaceuticals, Theravance, Novartis, and Exalenz Bioscience Ltd., outside the submitted work. A.G-C. reports other fees from Terumo, and BTG, outside the submitted work. V.H-G. reports other fees from W. L. Gore & Associates, outside the submitted work.

Auteurs

Oana Nicoară-Farcău (O)

Department of Hepatology, Regional Institute of Gastroenterology and Hepatology "Octavian Fodor," "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Liver Unit, Barcelona Hepatic Hemodynamic Laboratory, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi I i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Guillem Soy (G)

Liver Unit, Barcelona Hepatic Hemodynamic Laboratory, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi I i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Centro de Investigación Biomédica Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain.
Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver).

Marta Magaz (M)

Liver Unit, Barcelona Hepatic Hemodynamic Laboratory, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi I i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Centro de Investigación Biomédica Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain.
Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver).

Anna Baiges (A)

Liver Unit, Barcelona Hepatic Hemodynamic Laboratory, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi I i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Centro de Investigación Biomédica Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain.
Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver).

Fanny Turon (F)

Liver Unit, Barcelona Hepatic Hemodynamic Laboratory, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi I i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Centro de Investigación Biomédica Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain.
Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver).

Angeles Garcia-Criado (A)

Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver).
Department of Radiology, Hospital Clinic de Barcelona, Barcelona, Spain.

Marta Barrufet (M)

Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver).
Department of Radiology, Hospital Clinic de Barcelona, Barcelona, Spain.

Marta Burrel (M)

Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver).
Department of Radiology, Hospital Clinic de Barcelona, Barcelona, Spain.

Virginia Hernández-Gea (V)

Liver Unit, Barcelona Hepatic Hemodynamic Laboratory, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi I i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Centro de Investigación Biomédica Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain.
Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver).

Juan Carlos García-Pagán (JC)

Liver Unit, Barcelona Hepatic Hemodynamic Laboratory, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi I i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Centro de Investigación Biomédica Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain.
Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver).

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › New Insights into the Pathogenesis, Risk...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fibrose › Cirrhose du foie › New Insights into the Pathogenesis, Risk...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › New Insights into the Pathogenesis, Risk...
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Embolie et thrombose › Thrombose › Thrombose veineuse › New Insights into the Pathogenesis, Risk...