Comparison of the Morphology of the Foveal Pit Between African and Caucasian Populations.
anatomy
fovea
macula
optical coherence tomography
retina
Journal
Translational vision science & technology
ISSN: 2164-2591
Titre abrégé: Transl Vis Sci Technol
Pays: United States
ID NLM: 101595919
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
26
08
2019
accepted:
24
02
2020
entrez:
22
8
2020
pubmed:
22
8
2020
medline:
22
8
2020
Statut:
epublish
Résumé
The purpose of this study was to characterize foveal pit morphology in an African (Ghanaian) population, to compare it to that of a Caucasian group and to determine if it varied with age in the two populations. The depth, diameter, slope, and volume of the foveal pit were interpolated from optical coherence tomography volume scans recorded in 84 Ghanaian and 37 Caucasian individuals. Their association with age, sex, and ethnicity was investigated using multilevel regression models. The foveal pit differed significantly in width, slope, and volume between Ghanaian men and women ( The morphology of the foveal pit differs between African and Caucasian individuals. These anatomic differences should be considered when examining differences in prevalence and clinical features of vitreoretinal disorders involving the fovea between the two populations. Differences in retinal anatomy may partly explain variations in the prevalence and clinical features of retinal diseases between Africans and Caucasians. Such differences should be adequately considered in diagnoses and monitoring of ocular diseases in patients with African ancestry.
Identifiants
pubmed: 32821496
doi: 10.1167/tvst.9.5.24
pii: TVST-19-1867
pmc: PMC7401974
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Pagination
24Subventions
Organisme : NEI NIH HHS
ID : R01 EY024969
Pays : United States
Organisme : NEI NIH HHS
ID : R24 EY017404
Pays : United States
Informations de copyright
Copyright 2020 The Authors.
Déclaration de conflit d'intérêts
Disclosure: M.A. Zouache, None; G. Silvestri, None; W.M. Amoaku, None; V. Silvestri, None; W.C. Hubbard, None; C. Pappas, None; S. Akafo, None; S. Lartey, None; R.R. Mastey, None; J. Carroll, None; G.S. Hageman, Voyant Biotherapeutics, LLC (C, I)
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