Aspirin for Primary Prevention of Cardiovascular Disease.
Aspirin
Cardiovascular diseases
Primary prevention
Journal
Journal of lipid and atherosclerosis
ISSN: 2287-2892
Titre abrégé: J Lipid Atheroscler
Pays: Korea (South)
ID NLM: 101610890
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
06
02
2019
revised:
26
07
2019
accepted:
29
07
2019
entrez:
22
8
2020
pubmed:
22
8
2020
medline:
22
8
2020
Statut:
ppublish
Résumé
Aspirin has been used for decades for the primary and secondary prevention of cardiovascular disease (CVD). The effect of aspirin in secondary prevention is well-known but is still debatable for primary prevention. Despite the controversy, aspirin is believed to have a beneficial effect in primary prevention and has been widely used. However, whether the doubts concerning the wide use of aspirin are correct has resulted in the publication of data from several large clinical trials recently. There are several clinical guidelines from various international organizations on the use of aspirin for the primary prevention of CVD, and they offer some conflicting recommendations. A reduction in the overall incidence of CVD with the development of modern prevention therapies has weakened the impact of aspirin in primary prevention. Large randomized clinical trials have found decreased or no difference in CVD events but a significant increase in the risk of bleeding. Taking aspirin for the primary prevention of CVD is no longer recommended, especially for patients who have a low to moderate risk. An assessment of the balance between the benefits and risks of aspirin use should be considered.
Identifiants
pubmed: 32821706
doi: 10.12997/jla.2019.8.2.162
pmc: PMC7379119
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
162-172Informations de copyright
Copyright © 2019 The Korean Society of Lipid and Atherosclerosis.
Déclaration de conflit d'intérêts
Conflict of Interest: The authors have no conflicts of interest to disclose.
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