Immunological tests and their interpretation in uveitis.
Infectious
investigations
non-infectious
novel infections
uveitis
Journal
Indian journal of ophthalmology
ISSN: 1998-3689
Titre abrégé: Indian J Ophthalmol
Pays: India
ID NLM: 0405376
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
entrez:
23
8
2020
pubmed:
23
8
2020
medline:
15
5
2021
Statut:
ppublish
Résumé
Uveitis is a complex disorder including both infectious and non-infectious etiologies. Clinical diagnosis is a challenge because many diseases share common clinical signs. Laboratory support is crucial for confirming the clinical diagnosis. Laboratory diagnosis includes direct tests and indirect tests. For example smear, culture, and molecular diagnostics demonstrate the pathogens, hence they are direct tests. Immunologic tests employ an antigen to detect presence of antibodies to a pathogen, or an antibody to detect the presence of an antigen, of the pathogen in the specimens. The immunological tests used in laboratories are made by producing artificial antibodies that exactly "match" the pathogen in question. When these antibodies come into contact with a sample they bind to the matching pathogen if found in the sample. Hence they are grouped under indirect evidence. There are several investigations in uveitis to reach the confirmed diagnosis including microbiological, immunological, imaging and molecular diagnostic testing. In this section we will discuss immunological investigations of infectious and non-infectious uveitis.
Identifiants
pubmed: 32823389
pii: IndianJOphthalmol_2020_68_9_1737_292582
doi: 10.4103/ijo.IJO_570_20
pmc: PMC7690523
doi:
Substances chimiques
Antibodies
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1737-1748Commentaires et corrections
Type : CommentIn
Type : CommentIn
Déclaration de conflit d'intérêts
None
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