Multiple Micronutrients and Docosahexaenoic Acid Supplementation during Pregnancy: A Randomized Controlled Study.
Adolescent
Adult
Biomarkers
/ blood
Dietary Supplements
Docosahexaenoic Acids
/ administration & dosage
Female
Fetal Blood
/ metabolism
Fetal Development
/ drug effects
Humans
Infant, Newborn
Maternal Nutritional Physiological Phenomena
Micronutrients
/ administration & dosage
Nutritional Status
Pregnancy
Pregnancy Trimesters
/ blood
Prenatal Care
/ methods
Treatment Outcome
Vitamin D
/ blood
Young Adult
docosahexaenoic acid
long-chain polyunsaturated fatty acids
maternal biomarkers
micronutrients
neurodevelopment
pregnant women
supplementation
vitamin D
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
13 Aug 2020
13 Aug 2020
Historique:
received:
20
07
2020
revised:
08
08
2020
accepted:
11
08
2020
entrez:
23
8
2020
pubmed:
23
8
2020
medline:
18
3
2021
Statut:
epublish
Résumé
Maternal dietary intake during pregnancy needs to meet increased nutritional demands to maintain metabolism and to support fetal development. Docosahexaenoic acid (DHA) is essential for fetal neuro-/visual development and in immunomodulation, accumulating rapidly within the developing brain and central nervous system. Levels available to the fetus are governed by the maternal diet. In this multicenter, parallel, randomized controlled trial, we evaluated once-daily supplementation with multiple micronutrients and DHA (i.e., multiple micronutrient supplementation, MMS) on maternal biomarkers and infant anthropometric parameters during the second and third trimesters of pregnancy compared with no supplementation. Primary efficacy endpoint: change in maternal red blood cell (RBC) DHA (
Identifiants
pubmed: 32823606
pii: nu12082432
doi: 10.3390/nu12082432
pmc: PMC7468952
pii:
doi:
Substances chimiques
Biomarkers
0
Micronutrients
0
Vitamin D
1406-16-2
Docosahexaenoic Acids
25167-62-8
Types de publication
Journal Article
Multicenter Study
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Bayer Consumer Care AG, Basel, Switzerland
ID : NA
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