Breast-Specific Epigenetic Regulation of DeltaNp73 and Its Role in DNA-Damage-Response of

BRCA-mutation DNA methylation cancer susceptibility deltaNp73 tissue-specificity

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
21 Aug 2020
Historique:
received: 29 07 2020
revised: 13 08 2020
accepted: 18 08 2020
entrez: 23 8 2020
pubmed: 23 8 2020
medline: 23 8 2020
Statut: epublish

Résumé

The function of BRCA1/2 proteins is essential for maintaining genomic integrity in all cell types. However, why women who carry deleterious germline mutations in

Identifiants

pubmed: 32825620
pii: cancers12092367
doi: 10.3390/cancers12092367
pmc: PMC7564633
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Israel Cancer Association
ID : ICA #20160039
Organisme : Cancer Biology Research Center, Tel Aviv University
ID : CBRC, TAU #0601243842

Références

Cancer Cell. 2002 Mar;1(2):129-32
pubmed: 12086871
Lancet. 2005 Nov 19;366(9499):1784-93
pubmed: 16298215
Mol Cell. 2009 Aug 28;35(4):534-41
pubmed: 19716796
Lancet. 2018 Sep 1;392(10149):777-786
pubmed: 30100054
Cell. 2017 Jun 1;169(6):1105-1118.e15
pubmed: 28575672
Cell Cycle. 2016;15(5):621-7
pubmed: 26822887
Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10869-74
pubmed: 11553815
Annu Rev Pathol. 2009;4:461-87
pubmed: 18954285
Genes Dev. 2010 Mar 15;24(6):549-60
pubmed: 20194434
Science. 2015 Jan 2;347(6217):78-81
pubmed: 25554788
Elife. 2017 Nov 06;6:
pubmed: 29106372
Nat Commun. 2015 Jun 24;6:7505
pubmed: 26106036
Cancer Res. 2002 Jul 1;62(13):3598-602
pubmed: 12097259
J Vis Exp. 2013 Jan 03;(71):
pubmed: 23328888
Nat Commun. 2014 Nov 17;5:5496
pubmed: 25400221
Nucleic Acids Res. 2006 Feb 06;34(3):840-52
pubmed: 16464822
Science. 2014 Mar 28;343(6178):1470-5
pubmed: 24675954
Nat Genet. 2009 Feb;41(2):178-186
pubmed: 19151715
Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17773-8
pubmed: 21987798
Cancer Res. 2014 May 15;74(10):2773-2784
pubmed: 24638981
Br J Cancer. 2007 Jan 15;96(1):11-5
pubmed: 17213823
Mol Cell Biol. 2000 Oct;20(20):7450-9
pubmed: 11003642
Mol Cell Biol. 2003 Aug;23(16):5540-55
pubmed: 12897129
PLoS One. 2014 Mar 20;9(3):e91805
pubmed: 24651077
Nat Rev Cancer. 2007 Mar;7(3):165-8
pubmed: 17332760
J Exp Med. 2002 Sep 16;196(6):765-80
pubmed: 12235210
Cell Death Differ. 2001 Dec;8(12):1213-23
pubmed: 11753569
Trends Genet. 2003 Jun;19(6):312-5
pubmed: 12801723
Genes Dev. 2010 Mar 15;24(6):517-20
pubmed: 20231313
Mol Cancer. 2009 Aug 11;8:61
pubmed: 19671150
Genes Dev. 2008 Oct 1;22(19):2677-91
pubmed: 18805989
Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):797-802
pubmed: 19139399
J Biol Chem. 2000 Oct 13;275(41):31869-75
pubmed: 10884389
Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2230-2234
pubmed: 28193856
Oncogene. 2015 Aug 13;34(33):4287-99
pubmed: 25381823
Science. 1997 Nov 7;278(5340):1043-50
pubmed: 9353177
Cancers (Basel). 2018 Dec 14;10(12):
pubmed: 30558184
J Clin Pathol. 2018 Jan;71(1):52-58
pubmed: 28743687
Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10642-E10651
pubmed: 30352856
Nat Protoc. 2009;4(4):495-505
pubmed: 19300443
Cell. 2010 Apr 16;141(2):243-54
pubmed: 20362325
Nat Protoc. 2006;1(6):2643-9
pubmed: 17406520

Auteurs

Ayelet Avraham (A)

Department of Oncology, Shamir Medical Center affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo 7033001, Israel.

Susanna Feldman (S)

Department of Oncology, Shamir Medical Center affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo 7033001, Israel.

Sean Soonweng Cho (SS)

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

Ayala Kol (A)

Department of Oncology, Shamir Medical Center affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo 7033001, Israel.

Lior Heler (L)

Department of Plastic Surgery, Shamir Medical Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo 7033001, Israel.

Emmanuela Riklin-Nahmias (E)

Department of Pathology, Shamir Medical Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo 7033001, Israel.

Avishay Sella (A)

Department of Oncology, Shamir Medical Center affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo 7033001, Israel.

Tamar Karni (T)

Department of Surgery, Shamir Medical Center and the Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo 7033001, Israel.

Tanir M Allweis (TM)

Department of General Surgery, Kaplan Medical Center, Rehovot and the Faculty of Medicine, The Hebrew University, Jerusalem 7661041, Israel.

Saraswati Sukumar (S)

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

Ella Evron (E)

Department of Oncology, Kaplan Medical Center, Rehovot and the Faculty of Medicine, The Hebrew University, Jerusalem 7661041, Israel.

Classifications MeSH