Blood pressure and kidney disease: chicken or egg (or both)?
Journal
Kidney international
ISSN: 1523-1755
Titre abrégé: Kidney Int
Pays: United States
ID NLM: 0323470
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
30
04
2020
accepted:
06
05
2020
entrez:
24
8
2020
pubmed:
24
8
2020
medline:
22
6
2021
Statut:
ppublish
Résumé
A recent study supports the concept that reduced kidney function causes higher blood pressure, but it found no evidence of causality in the opposite direction. We describe the method of bidirectional Mendelian randomization that was used to explore the direction of the causal relationship between kidney function and blood pressure, and examine the assumptions required for these analyses to give valid results.
Identifiants
pubmed: 32828236
pii: S0085-2538(20)30700-6
doi: 10.1016/j.kint.2020.05.048
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
547-549Subventions
Organisme : Medical Research Council
ID : MC_U137686853
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_00017/3
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_12026/5
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R007764/1
Pays : United Kingdom
Informations de copyright
Copyright © 2020 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.