A cell cycle checkpoint for the endoplasmic reticulum.

Cell Cycle Checkpoints / genetics Cell Division / genetics Chromosome Segregation / genetics DNA Replication / genetics Endoplasmic Reticulum / genetics Endoplasmic Reticulum Stress / genetics Humans Saccharomyces cerevisiae / genetics
Cell cycle Cell cycle checkpoint ER cell cycle surveillance (ERSU) checkpoint ER stress Endoplasmic reticulum Reticulon SLT2 MAP Kinase

Journal

Biochimica et biophysica acta. Molecular cell research
ISSN: 1879-2596
Titre abrégé: Biochim Biophys Acta Mol Cell Res
Pays: Netherlands
ID NLM: 101731731

Informations de publication

Date de publication:
12 2020
Historique:
received: 22 03 2020
revised: 10 08 2020
accepted: 12 08 2020
pubmed: 24 8 2020
medline: 9 1 2021
entrez: 24 8 2020
Statut: ppublish

Résumé

The generation of new cells is one of the most fundamental aspects of cell biology. Proper regulation of the cell cycle is critical for human health, as underscored by many diseases associated with errors in cell cycle regulation, including both cancer and hereditary diseases. A large body of work has identified regulatory mechanisms and checkpoints that ensure accurate and timely replication and segregation of chromosomal DNA. However, few studies have evaluated the extent to which similar checkpoints exist for the division of cytoplasmic components, including organelles. Such checkpoint mechanisms might be crucial for compartments that cannot be generated de novo, such as the endoplasmic reticulum (ER). In this review, we highlight recent work in the model organism Saccharomyces cerevisiae that led to the discovery of such a checkpoint that ensures that cells inherit functional ER into the daughter cell.

Identifiants

DOI: 10.1016/j.bbamcr.2020.118825 PMID: 32828757 PMC: PMC7558805
pubmed: 32828757
pii: S0167-4889(20)30183-X
doi: 10.1016/j.bbamcr.2020.118825
pmc: PMC7558805
mid: NIHMS1630701
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

118825

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM087415
Pays : United States

Informations de copyright

Copyright © 2020 The Author. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The author declares no competing or financial interest on the review.

Auteurs

Maho Niwa (M)

Division of Biological Sciences, Section of Molecular Biology, University of California San Diego, NSB#1, Rm 5328, 9500 Gilman Drive, La Jolla, CA 92093-0377, United States of America. Electronic address: mniwarosen@ucsd.edu.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques cellulaires › Cycle cellulaire › Points de contrôle du cycle cellulaire › A cell cycle checkpoint for the endoplasmic reticulum.
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › Division cellulaire › A cell cycle checkpoint for the endoplasmic reticulum.
questionsmedicales.fr › Phénomènes génétiques › Division du noyau cellulaire › Ségrégation des chromosomes › A cell cycle checkpoint for the endoplasmic reticulum.
questionsmedicales.fr › Phénomènes génétiques › Réplication de l'ADN › A cell cycle checkpoint for the endoplasmic reticulum.
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Réticulum endoplasmique › A cell cycle checkpoint for the endoplasmic reticulum.
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Stress du réticulum endoplasmique › A cell cycle checkpoint for the endoplasmic reticulum.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A cell cycle checkpoint for the endoplasmic reticulum.
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Saccharomyces › Saccharomyces cerevisiae › A cell cycle checkpoint for the endoplasmic reticulum.