Toward the Target: Tilorone, Quinacrine, and Pyronaridine Bind to Ebola Virus Glycoprotein.
Journal
ACS medicinal chemistry letters
ISSN: 1948-5875
Titre abrégé: ACS Med Chem Lett
Pays: United States
ID NLM: 101521073
Informations de publication
Date de publication:
13 Aug 2020
13 Aug 2020
Historique:
received:
01
06
2020
accepted:
23
07
2020
entrez:
25
8
2020
pubmed:
25
8
2020
medline:
25
8
2020
Statut:
epublish
Résumé
Pyronaridine, tilorone, and quinacrine were recently identified by a machine learning model and demonstrated
Identifiants
pubmed: 32832035
doi: 10.1021/acsmedchemlett.0c00298
pmc: PMC7430956
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1653-1658Subventions
Organisme : NCATS NIH HHS
ID : R21 TR001718
Pays : United States
Organisme : NIGMS NIH HHS
ID : R44 GM122196
Pays : United States
Informations de copyright
Copyright © 2020 American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare the following competing financial interest(s): S.E. is CEO of Collaborations Pharmaceuticals, Inc. T.R.L. is an employee at Collaborations Pharmaceuticals, Inc. Collaborations Pharmaceuticals, Inc. has obtained FDA orphan drug designations for pyronaridine, tilorone, and quinacrine for use against Ebola.
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