Long term-follow-up multicenter feasibility study of ICG fluorescence-navigated sentinel node biopsy in oral cancer.
head and neck cancer
indocyanine green
minimally invasive treatment
near-infrared fluorescence
sentinel node
Journal
Molecular and clinical oncology
ISSN: 2049-9450
Titre abrégé: Mol Clin Oncol
Pays: England
ID NLM: 101613422
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
08
03
2020
accepted:
17
07
2020
entrez:
25
8
2020
pubmed:
25
8
2020
medline:
25
8
2020
Statut:
ppublish
Résumé
In the current study, the utility of sentinel node (SN) identification using indocyanine green (ICG) was investigated for oral cancers in the clinical N0 stage. The current study was a prospective, multicentre, phase II clinical trial that was conducted in Japan. A total of 18 patients were included. Before surgery, the patients underwent lymphoscintigraphy to map the SNs. During surgery, radioactive isotope (RI) mapping was used to detect the SNs, and ICG was subsequently injected. ICG mapping of the SNs was then performed through the skin. The primary tumour was resected, and a neck flap was elevated for neck dissection, followed by SN biopsy (SNB) using RI or ICG mapping. With the RI method, a total of 63 SNs were detected. Among these SNs, 8 (12.7%) were positive for metastasis, including those with isolated tumour cells (ITCs). The median number of SNs per patient identified by SNB was 4. With the ICG method, a total of 67 SNs were detected. Among these SNs, 7 (10.4%) were positive for metastasis, including those with ITCs. The median number of SNs per patient identified by SNB was 4 (range, 1-6). The 5-year overall survival (OS) of all patients was 83.3%, and the 5-year disease-free survival (DFS) of all patients was 76.7%. The neck compression technique is a simple method that can be used to facilitate surgical procedures of ICG fluorescence navigated SNB for head and neck cancer.
Identifiants
pubmed: 32832084
doi: 10.3892/mco.2020.2111
pii: MCO-0-0-02111
pmc: PMC7439131
doi:
Types de publication
Journal Article
Langues
eng
Pagination
41Informations de copyright
Copyright: © Yokoyama et al.
Références
Ann Otol Rhinol Laryngol. 2010 Apr;119(4):225-32
pubmed: 20433020
World J Surg Oncol. 2015 Sep 17;13:278
pubmed: 26381239
Ann Surg Oncol. 2011 Feb;18(2):490-6
pubmed: 20652641
Auris Nasus Larynx. 2017 Jun;44(3):319-326
pubmed: 27496008
Head Neck. 2015 Apr;37(4):573-8
pubmed: 24677355
Ann Surg Oncol. 2011 Jul;18(7):2042-7
pubmed: 21298353
J Surg Oncol. 2012 Jul 1;106(1):41-5
pubmed: 22252373
JAMA Otolaryngol Head Neck Surg. 2016 Sep 1;142(9):857-65
pubmed: 27442962
J Craniomaxillofac Surg. 2013 Dec;41(8):721-7
pubmed: 23528669
Oral Oncol. 2013 Aug;49(8):771-7
pubmed: 23735238
Head Neck. 2011 Sep;33(9):1260-4
pubmed: 21837694
N Engl J Med. 2015 Aug 6;373(6):521-9
pubmed: 26027881
Ann Surg Oncol. 2010 Jul;17(7):1787-93
pubmed: 20162462
Head Neck. 1997 Jan;19(1):14-9
pubmed: 9030939
Otolaryngol Head Neck Surg. 2014 Aug;151(2):279-85
pubmed: 24732687
Int J Oral Maxillofac Surg. 2015 Oct;44(10):1212-7
pubmed: 26209419
Head Neck. 2009 Apr;31(4):503-12
pubmed: 19156833
Head Neck. 2019 Aug;41(8):2655-2664
pubmed: 30896058
Int J Oral Maxillofac Surg. 2014 Nov;43(11):1307-12
pubmed: 25128262
Anticancer Res. 2015 Mar;35(3):1669-74
pubmed: 25750326
Cancer. 1999 Dec 15;86(12):2668-73
pubmed: 10594862
Arch Otolaryngol Head Neck Surg. 2003 Oct;129(10):1105-9
pubmed: 14568797
Am J Surg. 1990 Oct;160(4):405-9
pubmed: 2221244
J Clin Oncol. 2010 Mar 10;28(8):1395-400
pubmed: 20142602
World J Surg. 2011 Jan;35(1):154-8
pubmed: 20931198
Bone Marrow Transplant. 2013 Mar;48(3):452-8
pubmed: 23208313
Oral Oncol. 2013 Jan;49(1):15-9
pubmed: 22939692
Ann Surg Oncol. 2016 Feb;23(2):565-72
pubmed: 26467454
J Craniomaxillofac Surg. 2018 Aug;46(8):1379-1384
pubmed: 29907432
Head Neck. 2011 Sep;33(9):1315-21
pubmed: 21837702
Eur J Cancer. 2015 Dec;51(18):2777-84
pubmed: 26597442
Head Neck. 2003 Sep;25(9):758-62
pubmed: 12953312
Breast Cancer. 2012 Oct;19(4):343-8
pubmed: 21725656