Factors predicting normal visual acuity following anatomically successful macular hole surgery.


Journal

Acta ophthalmologica
ISSN: 1755-3768
Titre abrégé: Acta Ophthalmol
Pays: England
ID NLM: 101468102

Informations de publication

Date de publication:
May 2021
Historique:
received: 14 04 2020
accepted: 18 07 2020
pubmed: 25 8 2020
medline: 1 12 2021
entrez: 25 8 2020
Statut: ppublish

Résumé

To assess the incidence of normal vision following anatomically successful macular hole surgery and associated clinical variables. Multicentre, retrospective chart review. Preoperative, intraoperative and postoperative clinical data were extracted from electronic medical records from seven European vitreoretinal units. Inclusion criteria were as follows: eyes undergoing primary vitrectomy for idiopathic full-thickness macular hole from January 2015 to January 2018; postoperative macular hole closure confirmed by spectral domain optical coherence tomography (OCT); preoperative pseudophakia or phakic eyes receiving combined cataract surgery; one-year follow-up. The primary outcome was 'normal vision' defined as a final best-corrected visual acuity (BCVA) ≥ 20/25. Univariate, multivariate and decision-tree analyses were conducted to evaluate the clinical variables associated with 'normal vision'. Odds ratios (OR) and confidence intervals (CIs) were calculated. Of 327 eligible cases, 91 (27.8%) achieved 'normal vision' at 1 year. Multivariate analysis identified variables significantly associated with 'normal vision': shorter symptom duration (odds ratio [OR]=1.05; 95% confidence interval [CI]:1.02-1.09; p = 0.002), smaller preoperative OCT minimum linear diameter (OR per 100-micron increase = 1.65; 95%CI:1.31-2.08; p < 0.001) and better mean preoperative BCVA (OR = 15.13; 95%CI: 3.59-63.65; p < 0.001). The decision-tree analysis found that the most significant variable associated with 'normal vision' was symptom duration. 'Normal vision' was achieved in 70.6% of eyes operated within one week from symptom onset and in 45% of eyes with symptom duration between 1 and 3 weeks. These findings suggested urgent surgery is justified for small macular holes of short duration.

Identifiants

pubmed: 32833307
doi: 10.1111/aos.14575
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

e324-e329

Informations de copyright

© 2020 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

Références

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Auteurs

Matteo Fallico (M)

Department of Ophthalmology, University of Catania, Catania, Italy.

Timothy L Jackson (TL)

Department of Ophthalmology, King's College Hospital, King's College London, London, UK.

Argyrios Chronopoulos (A)

Department of Ophthalmology, Ludwigshafen Hospital, Ludwigshafen am Rhein, Germany.

Lars-Olof Hattenbach (LO)

Department of Ophthalmology, Ludwigshafen Hospital, Ludwigshafen am Rhein, Germany.

Antonio Longo (A)

Department of Ophthalmology, University of Catania, Catania, Italy.

Vincenza Bonfiglio (V)

Department of Ophthalmology, University of Catania, Catania, Italy.

Andrea Russo (A)

Department of Ophthalmology, University of Catania, Catania, Italy.

Teresio Avitabile (T)

Department of Ophthalmology, University of Catania, Catania, Italy.

Francesca Parisi (F)

Department of Ophthalmology, University of Catania, Catania, Italy.

Mario Romano (M)

Department of Ophthalmology, Gavazzeni - Castelli Hospital, Humanitas University, Rozzano, Italy.

Tito Fiore (T)

Division of Ophthalmology, Department of Surgery and Biomedical Science, S Maria della Misericordia Hospital, University of Perugia, Perugia, Italy.

Carlo Cagini (C)

Division of Ophthalmology, Department of Surgery and Biomedical Science, S Maria della Misericordia Hospital, University of Perugia, Perugia, Italy.

Marco Lupidi (M)

Division of Ophthalmology, Department of Surgery and Biomedical Science, S Maria della Misericordia Hospital, University of Perugia, Perugia, Italy.

Rino Frisina (R)

Department of Ophthalmology, University of Padova, Padova, Italy.

Lorenzo Motta (L)

Department of Ophthalmology, King's College Hospital, King's College London, London, UK.

Robert Rejdak (R)

Department of General Ophthalmology, Medical University of Lublin, Lublin, Poland.

Katarzyna Nowomiejska (K)

Department of General Ophthalmology, Medical University of Lublin, Lublin, Poland.

Mario Toro (M)

Department of General Ophthalmology, Medical University of Lublin, Lublin, Poland.

Luca Ventre (L)

Department of Surgical Sciences, Eye Clinic Section, University of Turin, Turin, Italy.

Michele Reibaldi (M)

Department of Surgical Sciences, Eye Clinic Section, University of Turin, Turin, Italy.

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