Prevalence of Cilioretinal Arteries: A systematic review and a prospective cross-sectional observational study.

Caucasian Hungarian Hungary arteries artery cilioretinal circulation fundus photography population prevalence retinal review vessels

Journal

Acta ophthalmologica
ISSN: 1755-3768
Titre abrégé: Acta Ophthalmol
Pays: England
ID NLM: 101468102

Informations de publication

Date de publication:
May 2021
Historique:
revised: 14 07 2020
received: 10 06 2020
accepted: 18 07 2020
pubmed: 25 8 2020
medline: 1 12 2021
entrez: 25 8 2020
Statut: ppublish

Résumé

To review studies focusing on cilioretinal arteries (CLRA) in order to assess the overall prevalence and establish the prevalence of CLRA in a Hungarian Caucasian population. METHODS #1: Systematic literature review of published studies with at least 100 participants. METHODS #2: Non-mydriatic digital colour photographs were taken of 1000 consecutively enrolled healthy Caucasian young adult volunteers. Images were graded by two trained independent observers. Number and location of identified cilioretinal arteries were recorded and statistically analysed. RESULTS #1: Prevalence of CLRA ranges from 6.9% to 49.5%. Detection with fluorescein angiography yields the highest values followed by fundus photography and ophthalmoscopy. Unilateral presence of CLRA is between 70.30% and 93.65%, and temporal location is between 80.77% and 100%. RESULTS #2: We found at least one CLRA in 36.5% of the participants and in 22.75% of all the examined eyes. Cilioretinal arteries (CLRA) were unilateral in 75.34% and bilateral in 24.66%. Of all the identified CLRA, 96.16% were originating from the temporal rim of the optic disc. We identified at least one temporal CLRA supplying the macula in 28% of the participants and 16.95% of the examined eyes. Prevalence of CLRA varies depending on identification method. Unilateral presence is unequivocally more frequent similarly to temporal location. From a risk of bias standpoint, high-quality studies are rare. Our data on the distribution pattern of CLRA are similar to that in the international literature. Based on our findings, we assume that slightly more than one-third of the Hungarian Caucasian population has a CLRA.

Identifiants

pubmed: 32833328
doi: 10.1111/aos.14592
doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e310-e318

Subventions

Organisme : Hungarian Scientific Academy
Organisme : National Research, Development and Innovation Fund
Organisme : Magyar Tudományos Akadémia
ID : Janos Bolyai Scholarship of the Hungarian Academy
Organisme : Nemzeti Kutatási Fejlesztési és Innovációs Hivatal
ID : TUDFO/51757/2019-ITM

Informations de copyright

© 2020 The Authors. Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation.

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Auteurs

Miklos Schneider (M)

Department of Ophthalmology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Department of Ophthalmology, Rigshospitalet, Glostrup, Denmark.

Adel Molnar (A)

Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Orsolya Angeli (O)

Department of Ophthalmology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Dorottya Szabo (D)

Department of Ophthalmology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Fruzsina Bernath (F)

Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Dorottya Hajdu (D)

Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Eszter Gombocz (E)

Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Balint Mate (B)

Department of Mechatronics, Optics and Mechanical Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Budapest, Hungary.

Balint Jiling (B)

Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Balazs Vince Nagy (BV)

Department of Mechatronics, Optics and Mechanical Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Budapest, Hungary.

Zoltan Zsolt Nagy (ZZ)

Department of Ophthalmology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Tunde Peto (T)

Centre for Public Health, Queen's University Belfast, Belfast, UK.
Research Unit of Ophthalmology, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

Andras Papp (A)

Department of Ophthalmology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

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