Evaluation of the exposure risk of SARS-CoV-2 in different hospital environment.
COVID-19
HCWs
Nucleic acid test
Occupational exposure risk
SARS-CoV-2
Journal
Sustainable cities and society
ISSN: 2210-6715
Titre abrégé: Sustain Cities Soc
Pays: Netherlands
ID NLM: 101735304
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
25
05
2020
revised:
16
07
2020
accepted:
18
07
2020
entrez:
25
8
2020
pubmed:
25
8
2020
medline:
25
8
2020
Statut:
ppublish
Résumé
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has imposed a significant impact on social and economic activities. As a high infectious pathogen, the existence of SARS-CoV-2 in public space is very important for its transmission. During the COVID-19 pandemic, hospitals are the main places to deal with the diseases. In this work, we evaluated the exposure risk of SARS-CoV-2 in hospital environment in order to protect healthcare workers (HCWs). Briefly, air and surface samples from 6 different sites of 3 hospitals with different protection levels were collected and tested for the SARS-CoV-2 nucleic acid by reverse transcription real-time fluorescence PCR method during the COVID-19 epidemic. We found that the positive rate of SARS-CoV-2 nucleic acid was 7.7 % in a COVID-19 respiratory investigation wards and 82.6 % in a ICUs with confirmed COVID-19 patients. These results indicated that in some wards of the hospital, such as ICUs occupied by COVID-19 patients, the nucleic acid of SARS-CoV-2 existed in the air and surface, which indicates the potential occupational exposure risk of HCWs. This study has clarified retention of SARS-CoV-2 in different sites of hospital, suggesting that it is necessary to monitor and disinfect the SARS-CoV-2 in hospital environment during COVID-19 pandemic, and will help to prevent the iatrogenic infection and nosocomial transmission of SARS-CoV-2 and to better protect the HCWs.
Identifiants
pubmed: 32834932
doi: 10.1016/j.scs.2020.102413
pii: S2210-6707(20)30634-X
pii: 102413
pmc: PMC7375302
doi:
Types de publication
Journal Article
Langues
eng
Pagination
102413Informations de copyright
© 2020 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
Références
N Engl J Med. 2020 Mar 26;382(13):1194-1196
pubmed: 32074416
N Engl J Med. 2020 Mar 26;382(13):1199-1207
pubmed: 31995857
Lancet. 2020 Feb 15;395(10223):470-473
pubmed: 31986257
Lancet. 2017 Feb 25;389(10071):805-814
pubmed: 28104287
Nat Med. 2020 Aug;26(8):1200-1204
pubmed: 32555424
Indian J Crit Care Med. 2019 May;23(5):227-231
pubmed: 31160840
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Mar;62(3):329-340
pubmed: 30783685
Clin Infect Dis. 2020 Feb 14;70(5):850-858
pubmed: 30963180
BMJ Open. 2019 Oct 1;9(10):e029971
pubmed: 31575536
Dtsch Med Wochenschr. 2020 May;145(10):670-674
pubmed: 32344440
Am J Infect Control. 2007 Dec;35(10 Suppl 2):S65-164
pubmed: 18068815
J Hosp Infect. 2018 Apr;98(4):328-330
pubmed: 29486215
Turk J Med Sci. 2020 Apr 17;50(SI-1):563-570
pubmed: 32299206
Indoor Air. 2015 Oct;25(5):462-74
pubmed: 25346039
Clin Microbiol Infect. 2012 Dec;18(12):1212-8
pubmed: 22192567
Sustain Cities Soc. 2020 Oct;61:102350
pubmed: 32834930
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
Nature. 2020 Feb;578(7796):515
pubmed: 32099122
J Med Virol. 2020 Apr;92(4):401-402
pubmed: 31950516
Lancet Infect Dis. 2006 Oct;6(10):641-52
pubmed: 17008173
Int J Antimicrob Agents. 2020 Mar;55(3):105924
pubmed: 32081636
Int J Occup Saf Ergon. 2016;22(2):241-5
pubmed: 26652205
N Engl J Med. 2020 May 21;382(21):2005-2011
pubmed: 32220208
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2018 Apr;61(4):371-373
pubmed: 29536112
GMS Hyg Infect Control. 2019 Dec 04;14:Doc20
pubmed: 32047719
N Engl J Med. 2020 May 7;382(19):1869
pubmed: 32220200
Gov Inf Q. 2020 Jul;37(3):101481
pubmed: 32313361
Lancet. 2020 Feb 29;395(10225):686-687
pubmed: 32122469
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Mil Med Res. 2020 Feb 6;7(1):4
pubmed: 32029004
N Engl J Med. 2020 Feb 20;382(8):692-694
pubmed: 31978293
Sustain Cities Soc. 2020 Nov;62:102372
pubmed: 32834935
Chin J Dent Res. 2020;23(2):105-107
pubmed: 32548601
J Med Microbiol. 2018 Dec;67(12):1761-1771
pubmed: 30372411
Microbes Infect. 2020 Mar;22(2):80-85
pubmed: 32087334
J Infect Public Health. 2013 Feb;6(1):27-34
pubmed: 23290090
Infect Control Hosp Epidemiol. 2020 Mar;41(3):259-266
pubmed: 32043434
Lancet. 2020 Feb 15;395(10223):507-513
pubmed: 32007143