Recent insights for the emerging COVID-19: Drug discovery, therapeutic options and vaccine development.
COVID-19
Coronavirus
Drug discovery
Precise prevention and control
SARS-CoV-2
Vaccine development
Journal
Asian journal of pharmaceutical sciences
ISSN: 2221-285X
Titre abrégé: Asian J Pharm Sci
Pays: Netherlands
ID NLM: 101535338
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
04
05
2020
revised:
29
05
2020
accepted:
21
06
2020
pubmed:
25
8
2020
medline:
25
8
2020
entrez:
25
8
2020
Statut:
ppublish
Résumé
SARS-CoV-2 has been marked as a highly pathogenic coronavirus of COVID-19 disease into the human population, causing over 5.5 million confirmed cases worldwide. As COVID-19 has posed a global threat with significant human casualties and severe economic losses, there is a pressing demand to further understand the current situation and develop rational strategies to contain the drastic spread of the virus. Although there are no specific antiviral therapies that have proven effective in randomized clinical trials, currently, the rapid detection technology along with several promising therapeutics for COVID-19 have mitigated its drastic transmission. Besides, global institutions and corporations have commenced to parse out effective vaccines for the prevention of COVID-19. Herein, the present review will give exhaustive details of extensive researches concerning the drug discovery and therapeutic options for COVID-19 as well as some insightful discussions of the status of COVID-19.
Identifiants
pubmed: 32837565
doi: 10.1016/j.ajps.2020.06.001
pii: S1818-0876(20)30564-X
pmc: PMC7335243
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
4-23Informations de copyright
© 2020 Shenyang Pharmaceutical University. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
The authors assert that there is no conflict of interests concerning the publication of this review.
Références
J Clin Microbiol. 2020 Apr 23;58(5):
pubmed: 32132196
J Microbiol Immunol Infect. 2020 Jun;53(3):436-443
pubmed: 32307245
Science. 2020 Jun 19;368(6497):1331-1335
pubmed: 32321856
Antimicrob Agents Chemother. 2014 Aug;58(8):4885-93
pubmed: 24841273
J Clin Virol. 2004 Dec;31(4):304-9
pubmed: 15494274
Hong Kong Med J. 2003 Dec;9(6):399-406
pubmed: 14660806
Lancet. 2020 Feb 15;395(10223):514-523
pubmed: 31986261
Nature. 2020 Mar;579(7798):270-273
pubmed: 32015507
Science. 2020 Mar 13;367(6483):1260-1263
pubmed: 32075877
Emerg Microbes Infect. 2020 Dec;9(1):382-385
pubmed: 32065055
Euro Surveill. 2020 Feb;25(5):
pubmed: 32046819
Microbes Infect. 2020 May - Jun;22(4-5):188-194
pubmed: 32302675
Expert Opin Drug Discov. 2020 Feb;15(2):159-177
pubmed: 31809605
Lancet. 2020 Feb 22;395(10224):565-574
pubmed: 32007145
Int J Biol Sci. 2020 Mar 15;16(10):1708-1717
pubmed: 32226288
Biochem Biophys Res Commun. 2004 Jul 2;319(3):746-52
pubmed: 15184046
N Engl J Med. 2020 May 7;382(19):1787-1799
pubmed: 32187464
J Immunol. 2011 Jun 15;186(12):7264-8
pubmed: 21576510
Nature. 2020 Aug;584(7819):120-124
pubmed: 32454512
N Engl J Med. 2020 Mar 26;382(13):1199-1207
pubmed: 31995857
Emerg Infect Dis. 2019 Jan;25(1):1-4
pubmed: 30560777
Chem Asian J. 2019 Nov 18;14(22):3962-3968
pubmed: 31389664
Cell Res. 2020 Apr;30(4):343-355
pubmed: 32231345
Lancet Respir Med. 2020 Apr;8(4):420-422
pubmed: 32085846
Radiology. 2020 Apr;295(1):202-207
pubmed: 32017661
Drug Discov Ther. 2020;14(1):58-60
pubmed: 32147628
Curr Opin Immunol. 2011 Jun;23(3):421-9
pubmed: 21530212
N Engl J Med. 2003 May 15;348(20):1947-8
pubmed: 12748313
Virol Sin. 2020 Jun;35(3):266-271
pubmed: 32125642
Euro Surveill. 2020 Jan;25(3):
pubmed: 31992387
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
Clin Microbiol Rev. 2007 Oct;20(4):660-94
pubmed: 17934078
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
Cell Res. 2020 Mar;30(3):269-271
pubmed: 32020029
Immune Netw. 2017 Oct;17(5):343-351
pubmed: 29093655
Antiviral Res. 2020 May;177:104762
pubmed: 32147496
Clin Microbiol Rev. 2001 Oct;14(4):778-809, table of contents
pubmed: 11585785
Pharmacol Res. 2020 Jun;156:104761
pubmed: 32205232
Antimicrob Agents Chemother. 2014;58(1):267-73
pubmed: 24145541
Clin Infect Dis. 2020 Jul 28;71(15):732-739
pubmed: 32150618
J Med Virol. 2020 Jun;92(6):589-594
pubmed: 32100876
Nat Med. 2020 Apr;26(4):450-452
pubmed: 32284615
Trends Mol Med. 2020 May;26(5):483-495
pubmed: 32359479
Emerg Infect Dis. 2020 Jul;26(7):1592-1595
pubmed: 32284092
J Virol. 2014 Apr;88(8):4353-65
pubmed: 24501399
Biosci Trends. 2020 Mar 16;14(1):72-73
pubmed: 32074550
Nat Rev Drug Discov. 2016 May;15(5):327-47
pubmed: 26868298
Cell. 2020 Apr 16;181(2):281-292.e6
pubmed: 32155444
Int J Antimicrob Agents. 2020 Mar;55(3):105924
pubmed: 32081636
J Infect Dis. 2015 Jan 1;211(1):80-90
pubmed: 25030060
Nature. 2020 Feb 7;:
pubmed: 33547428
J Microbiol Biotechnol. 2020 Mar 28;30(3):313-324
pubmed: 32238757
Science. 2017 Jul 14;357(6347):149-152
pubmed: 28706037
Lancet. 2003 Jul 26;362(9380):293-4
pubmed: 12892961
Chin J Nat Med. 2020 Mar;18(3):206-210
pubmed: 32245590
Nat Rev Rheumatol. 2020 Mar;16(3):155-166
pubmed: 32034323
JAMA. 2020 Apr 28;323(16):1582-1589
pubmed: 32219428
Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10012-7
pubmed: 15226499
Radiology. 2020 Apr;295(1):16-17
pubmed: 32017662
Thorax. 2004 Mar;59(3):252-6
pubmed: 14985565
Antimicrob Agents Chemother. 2016 Apr 22;60(5):2834-48
pubmed: 26926637
JAMA. 2020 Apr 14;323(14):1406-1407
pubmed: 32083643
Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9241-9243
pubmed: 32269081
Nat Rev Drug Discov. 2020 May;19(5):305-306
pubmed: 32273591
N Engl J Med. 2020 Mar 5;382(10):929-936
pubmed: 32004427
Viruses. 2019 Apr 04;11(4):
pubmed: 30987343
J Virol. 2020 Mar 17;94(7):
pubmed: 31996437
Nature. 2020 Apr 29;:
pubmed: 32350436
Nature. 2020 Aug;584(7819):115-119
pubmed: 32454513
Int J Infect Dis. 2014 Mar;20:42-6
pubmed: 24406736
J Hosp Infect. 2020 Mar;104(3):246-251
pubmed: 32035997
J Med Virol. 2020 May;92(5):476-478
pubmed: 32056235
Aging Dis. 2020 Mar 9;11(2):216-228
pubmed: 32257537
Nat Rev Cancer. 2008 Feb;8(2):108-20
pubmed: 18219306
Curr Biol. 2020 Apr 6;30(7):1346-1351.e2
pubmed: 32197085
Nat Biotechnol. 2020 May;38(5):515-518
pubmed: 32203294
Lancet Infect Dis. 2020 Apr;20(4):398-400
pubmed: 32113510
J Virol. 2014 Aug;88(16):8998-9009
pubmed: 24899182
Nat Rev Drug Discov. 2018 Apr;17(4):261-279
pubmed: 29326426
Lancet. 2020 Jun 13;395(10240):1845-1854
pubmed: 32450106
Kidney Int. 2020 Jul;98(1):219-227
pubmed: 32327202
Nat Rev Microbiol. 2013 Dec;11(12):836-48
pubmed: 24217413
Nat Rev Immunol. 2020 May;20(5):269-270
pubmed: 32273594
Lancet. 2020 May 22;:
pubmed: 32450107
Virol J. 2005 Aug 22;2:69
pubmed: 16115318
J Virol Methods. 2004 Sep 1;120(1):87-96
pubmed: 15234813
J Clin Microbiol. 2015 Aug;53(8):2722-6
pubmed: 26019210
Nature. 2020 Mar;579(7799):321
pubmed: 32179860
mBio. 2012 Nov 20;3(6):
pubmed: 23170002
Chin Med J (Engl). 2020 Jun 20;133(12):1390-1396
pubmed: 32251003
Nat Biotechnol. 2020 May;38(5):523-532
pubmed: 32203293
Nat Commun. 2020 Jan 10;11(1):222
pubmed: 31924756
Cochrane Database Syst Rev. 2012 Oct 17;10:CD004882
pubmed: 23076910
Biochem Biophys Res Commun. 2005 Jan 28;326(4):905-8
pubmed: 15607755
Curr Opin Virol. 2017 Apr;23:49-58
pubmed: 28412285
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Viruses. 2020 Mar 27;12(4):
pubmed: 32230900
Lancet. 2020 Feb 15;395(10223):473-475
pubmed: 32043983
Antimicrob Agents Chemother. 2014 Aug;58(8):4875-84
pubmed: 24841269
PLoS Biol. 2005 Oct;3(10):e324
pubmed: 16128623
J Immunol. 2004 Mar 1;172(5):2925-34
pubmed: 14978095
N Engl J Med. 2020 May 7;382(19):1851-1852
pubmed: 32187463
Arthritis Rheumatol. 2015 May;67(8):2176-84
pubmed: 25989906
J Infect. 2020 May;80(5):554-562
pubmed: 32169481
Science. 2020 Aug 14;369(6505):806-811
pubmed: 32434945
Science. 2020 Aug 14;369(6505):812-817
pubmed: 32434946
Vopr Virusol. 2008 Jul-Aug;53(4):9-13
pubmed: 18756809
Clin Infect Dis. 2020 Jul 28;71(15):841-843
pubmed: 32047895
Front Med. 2020 Apr;14(2):185-192
pubmed: 32170560
Biologicals. 2013 Mar;41(2):77-83
pubmed: 23190454
Allergy. 2020 Jul;75(7):1730-1741
pubmed: 32077115
N Engl J Med. 2020 Mar 26;382(13):1278-1280
pubmed: 32069388
Stem Cell Rev Rep. 2020 Jun;16(3):427-433
pubmed: 32281052
PLoS One. 2015 Apr 09;10(4):e0123126
pubmed: 25856093
Antivir Ther. 2004 Dec;9(6):1003-11
pubmed: 15651759
Cell. 2020 May 28;181(5):1036-1045.e9
pubmed: 32416070
Front Med. 2020 Apr;14(2):126-135
pubmed: 32240462
Vaccine. 2001 Mar 21;19(17-19):2206-9
pubmed: 11257334
N Engl J Med. 2020 Jun 11;382(24):2327-2336
pubmed: 32275812
J Formos Med Assoc. 2013 Jul;112(7):372-81
pubmed: 23883791
Antimicrob Agents Chemother. 2015 Feb;59(2):1088-99
pubmed: 25487801
Proc Natl Acad Sci U S A. 2020 Apr 14;117(15):8218-8221
pubmed: 32229574
Cell. 2020 Apr 16;181(2):271-280.e8
pubmed: 32142651
Antiviral Res. 2020 Jun;178:104791
pubmed: 32275914
Nature. 2020 Jul;583(7816):469-472
pubmed: 32408336
Lancet Respir Med. 2020 May;8(5):475-481
pubmed: 32105632
Nat Med. 2020 Apr;26(4):506-510
pubmed: 32284616
Lancet. 2003 May 10;361(9369):1615-7
pubmed: 12747883
Biochem Biophys Res Commun. 2004 Jun 4;318(3):719-25
pubmed: 15144898
Lancet. 2003 Apr 19;361(9366):1319-25
pubmed: 12711465
Lancet Infect Dis. 2006 Feb;6(2):67-9
pubmed: 16439323
JAMA. 2020 Apr 21;323(15):1502-1503
pubmed: 32105304
J Med Chem. 2006 May 4;49(9):2845-9
pubmed: 16640347
Cell. 2020 May 14;181(4):894-904.e9
pubmed: 32275855
Radiology. 2020 Aug;296(2):E41-E45
pubmed: 32049601
J Clin Med. 2020 Feb 07;9(2):
pubmed: 32046137
Gastroenterology. 2020 May;158(6):1831-1833.e3
pubmed: 32142773
Nature. 2020 Mar;579(7798):265-269
pubmed: 32015508