In vivo monitoring of carbonic anhydrase expression during the growth of larval zebrafish: a new environment-sensitive fluorophore for responsive turn-on fluorescence.
Animals
Carbonic Anhydrase II
/ antagonists & inhibitors
Carbonic Anhydrase Inhibitors
/ pharmacology
Density Functional Theory
Fluorescent Dyes
/ analysis
HeLa Cells
Humans
Larva
/ enzymology
Molecular Structure
Optical Imaging
Quinolines
/ chemical synthesis
Sulfonamides
/ pharmacology
Zebrafish
/ growth & development
Journal
Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838
Informations de publication
Date de publication:
28 Sep 2020
28 Sep 2020
Historique:
pubmed:
26
8
2020
medline:
1
5
2021
entrez:
26
8
2020
Statut:
ppublish
Résumé
This study monitors the dynamic progress of a newly developed background-free, target responsive strategy; 2,3-dihydroquinolin-4-imine (DQI) that can instantly respond to environmental changes with fluorescence enhancement, revealing a comprehensive platform for in vivo fluorescence bioimaging of mebrane-bound carbonic anhydrase II in HeLa cells and its expression during the growth of larval zebrafish.
Substances chimiques
Carbonic Anhydrase Inhibitors
0
Fluorescent Dyes
0
Quinolines
0
Sulfonamides
0
Carbonic Anhydrase II
EC 4.2.1.-
CA2 protein, human
EC 4.2.1.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM