Protocol registration issues of systematic review and meta-analysis studies: a survey of global researchers.


Journal

BMC medical research methodology
ISSN: 1471-2288
Titre abrégé: BMC Med Res Methodol
Pays: England
ID NLM: 100968545

Informations de publication

Date de publication:
25 08 2020
Historique:
received: 21 03 2020
accepted: 03 08 2020
entrez: 27 8 2020
pubmed: 28 8 2020
medline: 25 6 2021
Statut: epublish

Résumé

Although protocol registration of systematic reviews/meta-analysis (SR/MA) is still not mandatory, it is highly recommended that authors publish their SR/MA protocols prior to submitting their manuscripts for publication as recommended by the Cochrane guidelines for conducting SR/MAs. our aim was to assess the awareness, obstacles, and opinions of SR/MA authors about the protocol registration process. A cross-sectional survey study included the authors who published SR/MAs during the period from 2010 to 2016, and they were contacted for participation in our survey study. They were identified through the literature search of SR/MAs in Scopus database. An online questionnaire was sent to each participant via e-mail after receiving their approval to join the study. We have sent 6650 emails and received 275 responses. A total of 270 authors responses were complete and included in the final analysis. Our results has shown that PROSPERO was the most common database used for protocol registration (71.3%). The registration-to-acceptance time interval in PROSPERO was less than 1 month (99.1%). Almost half of the authors (44.2%) did not register their protocols prior to publishing their SR/MAs and according to their opinion that the other authors lack knowledge of protocol importance and mandance to be registered, was the most commonly reported reason (44.9%). A significant percenatge of respondents (37.4%) believed that people would steal their ideas from protocol databases, while only 5.3% reported that their SR/MA had been stolen. However, the majority (72.9%) of participants have agreed that protocol registries play a role in preventing unnecessary duplication of reviews. Finally, 37.4% of participants agree that SR/MA protocol registration should be mandatory. About half of the participants believes that the main reason for not registering protocols, is that the other authors lack knowledge concerning obligation and importance to register the SR/MA protocols in advance. Therefore, tools should be available to mandate protocol registration of any SRs beforehand and increasing awareness about the benefits of protocol registration among researchers.

Sections du résumé

BACKGROUND
Although protocol registration of systematic reviews/meta-analysis (SR/MA) is still not mandatory, it is highly recommended that authors publish their SR/MA protocols prior to submitting their manuscripts for publication as recommended by the Cochrane guidelines for conducting SR/MAs. our aim was to assess the awareness, obstacles, and opinions of SR/MA authors about the protocol registration process.
METHODS
A cross-sectional survey study included the authors who published SR/MAs during the period from 2010 to 2016, and they were contacted for participation in our survey study. They were identified through the literature search of SR/MAs in Scopus database. An online questionnaire was sent to each participant via e-mail after receiving their approval to join the study. We have sent 6650 emails and received 275 responses.
RESULTS
A total of 270 authors responses were complete and included in the final analysis. Our results has shown that PROSPERO was the most common database used for protocol registration (71.3%). The registration-to-acceptance time interval in PROSPERO was less than 1 month (99.1%). Almost half of the authors (44.2%) did not register their protocols prior to publishing their SR/MAs and according to their opinion that the other authors lack knowledge of protocol importance and mandance to be registered, was the most commonly reported reason (44.9%). A significant percenatge of respondents (37.4%) believed that people would steal their ideas from protocol databases, while only 5.3% reported that their SR/MA had been stolen. However, the majority (72.9%) of participants have agreed that protocol registries play a role in preventing unnecessary duplication of reviews. Finally, 37.4% of participants agree that SR/MA protocol registration should be mandatory.
CONCLUSION
About half of the participants believes that the main reason for not registering protocols, is that the other authors lack knowledge concerning obligation and importance to register the SR/MA protocols in advance. Therefore, tools should be available to mandate protocol registration of any SRs beforehand and increasing awareness about the benefits of protocol registration among researchers.

Identifiants

pubmed: 32842968
doi: 10.1186/s12874-020-01094-9
pii: 10.1186/s12874-020-01094-9
pmc: PMC7448304
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

213

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Auteurs

Gehad Mohamed Tawfik (GM)

Faculty of Medicine, Ain Shams University, Cairo, Egypt.
.

Hoang Thi Nam Giang (HTN)

.
The University of Da Nang, Da Nang, Vietnam.

Sherief Ghozy (S)

.
Neurosurgery Department, El Sheikh Zayed Specialized Hospital, Giza, Egypt.

Ahmed M Altibi (AM)

.
Henry Ford Allegiance Health, Henry Ford Health System, Jackson, MI, USA.

Hend Kandil (H)

.
Faculty of Medicine, Menofia University, Menofia, Egypt.

Huu-Hoai Le (HH)

.
Saigon General Hospital, Ho Chi Minh City, Vietnam.

Peter Samuel Eid (PS)

Faculty of Medicine, Ain Shams University, Cairo, Egypt.
.

Ibrahim Radwan (I)

Faculty of Medicine, Ain Shams University, Cairo, Egypt.
.

Omar Mohamed Makram (OM)

.
Faculty of Medicine, October 6 University, Giza, 12566, Egypt.

Tong Thi Thu Hien (TTT)

.
School of Medicine, Viet Nam National University, Ho Chi Minh City, Vietnam.

Mahmoud Sherif (M)

.
Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

As-Saba Hossain (AS)

.
Dhaka Medical College, Dhaka, Bangladesh.

Tai Luu Lam Thang (TLL)

.
Faculty of Medicine, Pham Ngoc Thach University, Ho Chi Minh City, Vietnam.

Livia Puljak (L)

Department of Anatomy, Histology and Embryology, University of Split School of Medicine, Soltanska 2, 21000, Split, Croatia.

Hosni Salem (H)

Urology Department, Faculty of Medicine, Cairo University, Giza, Egypt.

Tarek Numair (T)

School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, 852-8523, Japan.

Kazuhiko Moji (K)

School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, 852-8523, Japan.

Nguyen Tien Huy (NT)

School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, 852-8523, Japan. tienhuy@nagasaki-u.ac.jp.
Institute of Research and Development, Duy Tan University, Da Nang, 550000, Vietnam. tienhuy@nagasaki-u.ac.jp.

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Classifications MeSH