Restless legs syndrome: A new comorbidity in idiopathic pulmonary fibrosis.
Idiopathic pulmonary fibrosis
Interstitial lung disease
Restless legs syndrome
Sleep quality
Sleep-related movements disorders
Journal
Respiratory medicine
ISSN: 1532-3064
Titre abrégé: Respir Med
Pays: England
ID NLM: 8908438
Informations de publication
Date de publication:
Historique:
received:
05
10
2019
revised:
19
03
2020
accepted:
17
04
2020
entrez:
27
8
2020
pubmed:
28
8
2020
medline:
8
6
2021
Statut:
ppublish
Résumé
Sleep disorders have a high prevalence among patients with idiopathic pulmonary fibrosis (IPF). The prevalence of restless legs syndrome (RLS) is not known in these patients, neither is its clinical impact as a comorbidity. We investigated the association of RLS with IPF and characterized the clinical features of RLS in a cohort of IPF patients. Fifty patients with diagnosis of IPF were prospectively enrolled. RLS was diagnosed using the validated 5-item RLS criteria. Sleep quality was evaluated using the Pittsburgh Sleep Quality Index. The prevalence of RLS in the IPF group was compared to that observed in a group of 293 patients referred for suspect of sleep disorders. The relationships between RLS and clinical parameters were determined using multivariate logistic regression. Prevalence of RLS in the IPF group was significantly higher than in the control population of patients referred for sleep disorders (IPF: 24%, controls 10%: χ RLS is highly prevalent in IPF and significantly worsen sleep quality in these patients. The benefit/risk ratio of a specific therapeutic intervention for RLS in IPF should be assessed in further prospective research.
Identifiants
pubmed: 32843160
pii: S0954-6111(20)30122-0
doi: 10.1016/j.rmed.2020.105982
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105982Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.