The role of diet in unexpected poor response to ovarian stimulation: a cross-sectional study.
Diet
Glycaemic load
IVF
Ovarian response
Journal
Reproductive biomedicine online
ISSN: 1472-6491
Titre abrégé: Reprod Biomed Online
Pays: Netherlands
ID NLM: 101122473
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
14
05
2020
revised:
23
06
2020
accepted:
13
07
2020
pubmed:
28
8
2020
medline:
23
9
2021
entrez:
27
8
2020
Statut:
ppublish
Résumé
Is there an association between diet and poor ovarian response to ovarian stimulation in women with normal biomarkers of ovarian reserve? Women eligible for IVF at an Academic Fertility Center were invited to participate in this prospective cross-sectional study. The main inclusion criteria were age 18-39 years, body mass index 18-25 kg/m Out of the 303 women enrolled in the study, 48 (16%) showed an unexpected poor ovarian response. The frequency of poor responders increased with increasing glycaemic load, carbohydrate intake and fibre intake. When comparing the third with the first tertile (reference), the adjusted odds ratios for these were 3.91 (95% confidence interval [CI] 1.11-13.83, P = 0.04), 4.78 (95% CI 1.23-18.51, P = 0.02) and 6.03 (95% CI 1.18-30.77, P = 0.07), respectively. Elevated dietary glycaemic load as well as carbohydrate intake and fibre intake is significantly associated with unexpected poor ovarian response. Future interventional studies should clarify whether dietary modification might restore normal response.
Identifiants
pubmed: 32843305
pii: S1472-6483(20)30382-5
doi: 10.1016/j.rbmo.2020.07.011
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
874-883Informations de copyright
Copyright © 2020 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.