Quinidine hypersensitivity: a side effect of a forgotten antiarrhythmic.
arrhythmias
cardiovascular system
liver disease
pacing and electrophysiology
unwanted effects/adverse reactions
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
24 Aug 2020
24 Aug 2020
Historique:
entrez:
27
8
2020
pubmed:
28
8
2020
medline:
16
2
2021
Statut:
epublish
Résumé
Quinidine is one of the oldest antiarrhythmics known. Over the years, its use has decreased along with its side effects. Our case describes a 69-year-old woman with recurrent resistant ventricular tachycardia on Quinidine and Amiodarone who presented with acute liver toxicity. Drug-induced liver toxicity was at the top of our differential diagnosis list. Taking multiple factors into consideration, a decision was made to discontinue Quinidine, the patient's symptoms and lab abnormalities resolved within 1 week, yielding the diagnosis of Quinidine hypersensitivity.
Identifiants
pubmed: 32843415
pii: 13/8/e235528
doi: 10.1136/bcr-2020-235528
pmc: PMC7449301
pii:
doi:
Substances chimiques
Anti-Arrhythmia Agents
0
Quinidine
ITX08688JL
Amiodarone
N3RQ532IUT
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Commentaires et corrections
Type : RepublishedIn
Informations de copyright
© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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