Pseudohypoparathyroidism presenting with seizures: a case report and literature review.
hypocalcemia
pseudohypoparathyroidism
seizures
Journal
Intractable & rare diseases research
ISSN: 2186-3644
Titre abrégé: Intractable Rare Dis Res
Pays: Japan
ID NLM: 101586847
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
entrez:
27
8
2020
pubmed:
28
8
2020
medline:
28
8
2020
Statut:
ppublish
Résumé
Symptomatic hypocalcemia is frequently encountered in the Emergency Department, necessitating admission. It has a variety of underlying etiologies, with hypoparathyroidism and vitamin D deficiency being the most common. However, rarer etiologies such as pseudohypoparathyroidism, as was present in the current case, should not be overlooked. Reported here is a case of a young female patient presenting with generalized tonic clonic seizures. Electrocardiography revealed a prolonged QT interval which pointed towards a metabolic cause, and this was confirmed by laboratory results which indicated a low calcium level. A parathyroid pathology was obvious as the phosphate level was elevated. Pseudohypoparathyroidism, rather than hypoparathyroidism, was identified since the parathyroid hormone level was elevated. Other relevant differential diagnoses were excluded. The patient was treated with intravenous calcium initially and given regular oral calcium, calcitriol, and sevelamer.
Identifiants
pubmed: 32844075
doi: 10.5582/irdr.2020.03014
pmc: PMC7441037
doi:
Types de publication
Case Reports
Langues
eng
Pagination
166-170Informations de copyright
2020, International Research and Cooperation Association for Bio & Socio - Sciences Advancement.
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