COVID-19 and Cold Agglutinin Hemolytic Anemia.

autoantibodies thrombosis viral infection

Journal

TH open : companion journal to thrombosis and haemostasis
ISSN: 2512-9465
Titre abrégé: TH Open
Pays: Germany
ID NLM: 101715740

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 02 06 2020
accepted: 17 07 2020
entrez: 27 8 2020
pubmed: 28 8 2020
medline: 28 8 2020
Statut: epublish

Résumé

Novel coronavirus disease 2019 (COVID-19) has spread throughout the world and has infected close to 4 million people. It commonly presents with fever, cough, and fatigue. Due to the high inflammatory response, it is suggested that the coagulation cascade is enhanced causing thrombotic events for many patients. We describe a patient with clinical features of cerebrovascular accident, as well as documented blood clots in bilateral upper extremities. Labs revealed the presence of cold agglutinin hemolytic anemia. The association between cold agglutinin autoimmune hemolytic anemia and thrombotic events in COVID-19 patients has not been well investigated. The patient unfortunately passed away within 48 hours after admission. This case stresses the importance of considering a full workup to diagnose autoimmune hemolytic anemia (AIHA) in COVID-19 patients with thromboses and possible implications for management.

Identifiants

pubmed: 32844144
doi: 10.1055/s-0040-1715791
pii: 200037
pmc: PMC7440967
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e175-e177

Déclaration de conflit d'intérêts

Conflict of Interest None declared.

Références

Pediatr Blood Cancer. 2011 Aug;57(2):329-31
pubmed: 21671368
Front Immunol. 2020 Apr 07;11:590
pubmed: 32318071
Res Pract Thromb Haemost. 2020 Apr 09;4(4):628-635
pubmed: 32548562
Transfus Apher Sci. 2016 Apr;54(2):191-8
pubmed: 27156108
Otolaryngol Head Neck Surg. 2020 Jul;163(1):3-11
pubmed: 32369429
South Med J. 1990 Sep;83(9):1106-8
pubmed: 2402659
Intensive Care Med. 2020 Jun;46(6):1089-1098
pubmed: 32367170
J Clin Virol. 2020 Jun;127:104362
pubmed: 32305883
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Br J Haematol. 2020 Jul;190(1):29-31
pubmed: 32374906
Zhonghua Xue Ye Xue Za Zhi. 2020 Mar 14;41(3):245-247
pubmed: 32133824
BMJ Case Rep. 2018 Jul 10;2018:
pubmed: 29991541
Hematology Am Soc Hematol Educ Program. 2016 Dec 2;2016(1):226-231
pubmed: 27913484

Auteurs

Diana V Maslov (DV)

Department of Internal Medicine, Ochsner Clinic Foundation, New Orleans, Louisiana, United States.

Victoria Simenson (V)

Department of Internal Medicine, Ochsner Clinic Foundation, New Orleans, Louisiana, United States.

Suma Jain (S)

Department of Pulmonary and Critical Care, Ochsner Clinic Foundation, New Orleans, Louisiana, United States.

Ambuga Badari (A)

Department of Haematology and Oncology, Ochsner Clinic Foundation, New Orleans, Louisiana, United States.

Classifications MeSH